Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Study Phase : Approved
Recipient : Everest Medicines
Deal Size : $455.0 million
Deal Type : Acquisition
Details : Under the agreement, Everest Medicines will transfer all development and commercialization rights to Gilead for Trodelvy® (sacituzumab govitecan), a first-in-class Trop-2 directed antibody-drug conjugate, in Greater China and South Korea, among Other As...
Brand Name : Trodelvy
Molecule Type : Large molecule
Upfront Cash : $280.0 million
March 26, 2023
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Highest Development Status : Approved
Recipient : Everest Medicines
Deal Size : $455.0 million
Deal Type : Acquisition
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In single-arm Phase 2 study, Trodelvy demonstrated an ORR of 33.3 percent and a median DoR of 7.7 months, as determined by local assessment, in 108 adult TNBC patients who had previously received a median of three prior systemic therapies in the metastat...
Brand Name : Trodelvy
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 22, 2022
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Gilead Sciences
Deal Size : $21,000.0 million
Deal Type : Acquisition
Gilead Sciences Completes Acquisition of Immunomedics
Details : Gilead gains Trodelvy, Immunomedics' lead ADC, is the first ADC the FDA has approved for the treatment of people with metastatic triple-negative breast cancer and is also the first FDA-approved anti-Trop-2 ADC.
Brand Name : Trodelvy
Molecule Type : Large molecule
Upfront Cash : $15,000.0 million
October 23, 2020
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Gilead Sciences
Deal Size : $21,000.0 million
Deal Type : Acquisition
Lead Product(s) : Recombinant protein
Therapeutic Area : Oncology
Study Phase : Undisclosed
Recipient : ProteoNic
Deal Size : Undisclosed
Deal Type : Licensing Agreement
ProteoNic Announces Licensing of Technology for Production of Biologics to Immunomedics
Details : Under the agreement, Immunomedics gains commercial rights for application of ProteoNic’s technology platform to the development of specified proprietary products from mammalian cells.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
October 20, 2020
Lead Product(s) : Recombinant protein
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Recipient : ProteoNic
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Immunomedics Announces FDA Orphan Drug Designation of Trodelvy™ for Adult and Pediatric Glioblastoma
Details : Trodelvy has shown encouraging activity in an early-stage study in brain cancers, including partial responses in small cohorts of patients with brain metastasis from breast cancer and recurrent glioblastoma.
Brand Name : Trodelvy
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 12, 2020
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Trodelvy achieves a 27 percent overall response rate and a 5.9-month median duration of response in heavily-pretreated patients with metastatic urothelial cancer (mUC).
Brand Name : Trodelvy
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 19, 2020
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Immunomedic's Trodelvy™ Encouraging Early-Stage Clinical Results
Details : Results include partial responses in small cohort of patients with brain metastasis from breast cancer (BMBC) and recurrent glioblastoma (rGBM).
Brand Name : Trodelvy
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 18, 2020
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Gilead Sciences
Deal Size : $21,000.0 million
Deal Type : Acquisition
Gilead Sciences to Acquire Immunomedics
Details : Acquisition provides Gilead with TrodelvyTM (sacituzumab govitecan-hziy), a first-in-class Trop-2 directed antibody-drug conjugate that was granted accelerated approval by the FDA for the treatment of adult patients with metastatic triple-negative breast...
Brand Name : Trodelvy
Molecule Type : Large molecule
Upfront Cash : $15,000.0 million
September 13, 2020
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Gilead Sciences
Deal Size : $21,000.0 million
Deal Type : Acquisition
Lead Product(s) : Sacituzumab Govitecan,Atezolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : F. Hoffmann-La Roche
Deal Size : Undisclosed
Deal Type : Collaboration
Immunomedics Expands Collaboration with Roche Evaluating TrodelvyTM
Details : Collaboration aims to evaluate Trodelvy in combination with Tecentriq in patients with metastatic urothelial cancer and metastatic non-small cell lung cancer. Roche will be conducting two open-label, randomized Phase 1b/2 studies using its MORPHEUS platf...
Brand Name : Trodelvy
Molecule Type : Large molecule
Upfront Cash : Undisclosed
July 13, 2020
Lead Product(s) : Sacituzumab Govitecan,Atezolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : F. Hoffmann-La Roche
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Immunomedics Announces Positive Results from Phase 3 ASCENT Study of TRODELVYTM
Details : Trodelvy significantly improved progression-free survival (PFS) and overall survival (OS) in previously-treated brain metastasis negative patients with advanced mTNBC.
Brand Name : Trodelvy
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 06, 2020
Lead Product(s) : Sacituzumab Govitecan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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