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Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"IMP761","moa":"","graph1":"Immunology","graph2":"Phase I","graph3":"Immutep","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"","sponsorNew":"Immutep \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Immutep \/ Not Applicable"},{"orgOrder":0,"company":"Immutep","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Eftilagimod Alpha","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Immutep","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Immutep \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Immutep \/ Not Applicable"},{"orgOrder":0,"company":"Immutep","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"AUSTRALIA","productType":"Protein","year":"2025","type":"Inapplicable","leadProduct":"Eftilagimod Alpha","moa":"||MHC class II","graph1":"Oncology","graph2":"Phase II","graph3":"Immutep","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Immutep \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Immutep \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals by Immutep

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : IMP321 (Eftilagimod Alpha) is an MHC class II agonist protein, being investigated in combination with pembrolizumab for the treatment of resectable soft tissue sarcoma (STS).

                          Product Name : IMP321

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          January 22, 2025

                          Lead Product(s) : Eftilagimod Alpha,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : IMP761, a first-in-class immunosuppressive LAG-3 agonist antibody. Currently, it is being evaluated for the root cause of many autoimmune diseases by specifically silencing autoimmune memory T cells

                          Product Name : IMP761

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 17, 2024

                          Lead Product(s) : IMP761

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Efti (eftilagimod alpha), a soluble LAG-3 protein & MHC Class II agonist. It is being evaluated for first line treatment of metastatic non-small cell lung cancer & head & neck squamous cell cancer.

                          Product Name : Undisclosed

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 10, 2024

                          Lead Product(s) : Eftilagimod Alpha,Pembrolizumab,Carboplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : IMP321 (eftilagimod alpha), a soluble LAG-3 protein. It is being evaluated in combination with keytruda for first-line treatment of metastatic non-small cell lung cancer.

                          Product Name : IMP321

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 14, 2024

                          Lead Product(s) : Eftilagimod Alpha,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Merck & Co

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : IMP761, a first-in-class immunosuppressive LAG-3 agonist antibody. Currently, it is being evaluated for the root cause of many autoimmune diseases by specifically silencing autoimmune memory T cells

                          Product Name : IMP761

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 17, 2024

                          Lead Product(s) : IMP761

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : IMP321 (eftilagimod alpha) a soluble LAG-3 protein and MHC Class II agonist is being evaluated in combination with paclitaxel under evaluation for treatment of metastatic breast carcinoma.

                          Product Name : IMP321

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 03, 2024

                          Lead Product(s) : Eftilagimod Alpha,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : IMP321 (Eftilagimod Alpha) is an APC activator protein, being investigated in combination with pembrolizumab being investigated for soft tissue sarcoma.

                          Product Name : Efti

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 18, 2024

                          Lead Product(s) : Eftilagimod Alfa,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Merck & Co

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : IMP321 (Eftilagimod Alpha) is an APC activator protein, being investigated in combination with pembrolizumab as first-line treatment of recurrent or metastatic head & neck squamous cell carcinoma.

                          Product Name : Efti

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 16, 2024

                          Lead Product(s) : Eftilagimod Alfa,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : IMP761 is a first-in-class LAG-3 agonist antibody and Immutep's proprietary candidate being investigated for the treatment of autoimmune diseases.

                          Product Name : IMP761

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 14, 2024

                          Lead Product(s) : IMP761

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : IMP321 (eftilagimod alpha), a soluble LAG-3 protein. It is being evaluated in mid-stage clinical trial studies for first-line treatment of metastatic non-small cell lung cancer.

                          Product Name : Efti

                          Product Type :

                          Upfront Cash : Not Applicable

                          July 22, 2024

                          Lead Product(s) : Eftilagimod Alfa,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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