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Applicable","highestDevelopmentStatusID":"5","companyTruncated":"Immutep \/ Not Applicable"},{"orgOrder":0,"company":"Immutep","sponsor":"Charles River Laboratories","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"","productType":"Large molecule","year":"2023","type":"Agreement","leadProduct":"IMP761","moa":"","graph1":"Immunology","graph2":"Preclinical","graph3":"Immutep","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Immutep \/ Charles River Laboratories","highestDevelopmentStatusID":"4","companyTruncated":"Immutep \/ Charles River Laboratories"},{"orgOrder":0,"company":"Immutep","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"IMP761","moa":"","graph1":"Technology","graph2":"Phase 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molecule","year":"2024","type":"Not Applicable","leadProduct":"IMP761","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Immutep","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Immutep \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Immutep \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals for IMP761

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                          Top Deals by Deal Size (USD bn)

                          01

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : IMP761, a first-in-class immunosuppressive LAG-3 agonist antibody. Currently, it is being evaluated for the root cause of many autoimmune diseases by specifically silencing autoimmune memory T cells

                          Brand Name : IMP761

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 17, 2024

                          Lead Product(s) : IMP761

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : IMP761 is a first-in-class LAG-3 agonist antibody and Immutep's proprietary candidate being investigated for the treatment of autoimmune diseases.

                          Brand Name : IMP761

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 14, 2024

                          Lead Product(s) : IMP761

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : IMP761 is the world’s first therapeutic LAG-3 agonist antibody, which is being evaluated i the early-stage clinical rial studies for the treatment of autoimmune diseases.

                          Brand Name : IMP761

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          July 17, 2024

                          Lead Product(s) : IMP761

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : Under the agreement, Charles River will conduct a GLP toxicology study for IMP761, a first-in-class LAG-3 agonist antibody and Immutep's proprietary preclinical candidate for autoimmune diseases.

                          Brand Name : IMP761

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          May 29, 2023

                          Lead Product(s) : IMP761

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Charles River Laboratories

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          05

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : IMP761 is a first-in-class immunosuppressive agonist antibody to LAG-3. As a targeted immunosuppressive antibody, IMP761 has the potential to address the root cause of autoimmune diseases by specifically silencing autoimmune memory T cells.

                          Brand Name : IMP761

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 06, 2022

                          Lead Product(s) : IMP761

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : IMP761 is first-in-class immunosuppressive agonist antibody to LAG-3 has potential to address root cause of AID by specifically silencing autoimmune memory T cells that accumulate at disease site and express LAG-3.

                          Brand Name : IMP761

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          July 06, 2022

                          Lead Product(s) : IMP761

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : Under the agreement, Northway has already started developing a GMP-compliant manufacturing process of IMP761 and will manufacture IMP761 in large scale bioreactors. Planning for further pre-clinical and clinical development is ongoing.

                          Brand Name : IMP761

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          December 16, 2021

                          Lead Product(s) : IMP761

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Immutep

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          08

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : The claims of the patent are directed to Immutep’s pre-clinical product candidate, IMP761, and also to the use of IMP761 in the treatment of T-cell mediated inflammatory and autoimmune diseases.

                          Brand Name : IMP761

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 21, 2020

                          Lead Product(s) : IMP761

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : Using its STEP®-mAb technology, Batavia Biosciences has developed a pharmaceutical-grade, stable CHO cell line that produces significantly high product yields of IMP761.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 15, 2020

                          Lead Product(s) : IMP761

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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