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Corporation","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Cream","sponsorNew":"Incyte Corporation \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Incyte Corporation \/ Not Applicable"},{"orgOrder":0,"company":"Incyte Corporation","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Ruxolitinib Phosphate","moa":"","graph1":"Dermatology","graph2":"Approved","graph3":"Incyte Corporation","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Cream","sponsorNew":"Incyte Corporation \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Incyte Corporation \/ Not Applicable"},{"orgOrder":0,"company":"Incyte Corporation","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Ruxolitinib Phosphate","moa":"","graph1":"Dermatology","graph2":"Approved","graph3":"Incyte Corporation","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Cream","sponsorNew":"Incyte Corporation \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Incyte Corporation \/ Not Applicable"},{"orgOrder":0,"company":"Incyte Corporation","sponsor":"Replimune","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2023","type":"Collaboration","leadProduct":"INCB99280","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Incyte Corporation","amount2":0,"highestDevelopmentShortName":"Ph 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Corporation","highestDevelopmentStatusID":"12","companyTruncated":"Incyte Corporation \/ Incyte Corporation"},{"orgOrder":0,"company":"Incyte Corporation","sponsor":"Syndax Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Axatilimab","moa":"","graph1":"Immunology","graph2":"Phase III","graph3":"Incyte Corporation","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Incyte Corporation \/ Syndax Pharmaceuticals","highestDevelopmentStatusID":"10","companyTruncated":"Incyte Corporation \/ Syndax Pharmaceuticals"},{"orgOrder":0,"company":"Incyte Corporation","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","year":"2024","type":"Not 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Corporation","amount2":0.75,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0.75,"dosageForm":"","sponsorNew":"Incyte Corporation \/ Incyte Corporation","highestDevelopmentStatusID":"8","companyTruncated":"Incyte Corporation \/ Incyte Corporation"},{"orgOrder":0,"company":"Incyte Corporation","sponsor":"Escient Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","year":"2024","type":"Acquisition","leadProduct":"EP262","moa":"","graph1":"Dermatology","graph2":"Phase II","graph3":"Incyte Corporation","amount2":0.75,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0.75,"dosageForm":"","sponsorNew":"Incyte Corporation \/ Incyte Corporation","highestDevelopmentStatusID":"8","companyTruncated":"Incyte Corporation \/ Incyte Corporation"},{"orgOrder":0,"company":"Incyte Corporation","sponsor":"MacroGenics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Licensing Agreement","leadProduct":"Carboplatin","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Incyte Corporation","amount2":0.91000000000000003,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Incyte Corporation \/ Incyte Corporation","highestDevelopmentStatusID":"14","companyTruncated":"Incyte Corporation \/ Incyte Corporation"},{"orgOrder":0,"company":"Incyte Corporation","sponsor":"Syndax Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Axatilimab","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Incyte 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Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"INCB123667","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Incyte Corporation","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Incyte Corporation \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Incyte Corporation \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals by Incyte Corporation

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                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : INCB123667 is a novel, potent and selective oral small molecule inhibitor of CDK2, being investigated in Patients with Advanced Solid Tumors, Notably Ovarian Cancer.

                          Brand Name : INCB123667

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 14, 2024

                          Lead Product(s) : INCB123667

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Monjuvi (tafasitamab) is a humanized Fc-modified cytolytic CD19-targeting antibody, which is being evaluated in combination with lenalidomide & rituximab for the treatment of R/R follicular lymphoma.

                          Brand Name : Monjuvi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 15, 2024

                          Lead Product(s) : Tafasitamab,Rituximab,Lenalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Niktimvo (axatilimab) is an investigational monoclonal antibody that targets CSF-1R. It is approved for the treatment of chronic graft-versus-host disease.

                          Brand Name : Niktimvo

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 14, 2024

                          Lead Product(s) : Axatilimab

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved

                          Sponsor : Syndax Pharmaceuticals

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Under the license agreement, MacroGenics will focus on the development of Zynyz (retifanlimab), which is being evaluated in the late-stage trial studies for treating Squamous Cell Anal Carcinoma.

                          Brand Name : Zynyz

                          Molecule Type : Large molecule

                          Upfront Cash : $150.0 million

                          July 30, 2024

                          Lead Product(s) : Retifanlimab,Paclitaxel,Carboplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Recipient : MacroGenics

                          Deal Size : $905.0 million

                          Deal Type : Licensing Agreement

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Incyte will gain access to Escient's pipeline, which includes EP262, a potent, highly selective once-daily small molecule antagonist of MRGPRX2, currently undergoing evaluation for atopic dermatitis.

                          Brand Name : EP262

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          May 30, 2024

                          Lead Product(s) : EP262

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Recipient : Escient Pharmaceuticals

                          Deal Size : $750.0 million

                          Deal Type : Acquisition

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Incyte gains access to Escient's pipeline, including EP262, a selective small molecule antagonist of MRGPRX2 for atopic dermatitis.

                          Brand Name : EP262

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          April 23, 2024

                          Lead Product(s) : EP262

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Recipient : Escient Pharmaceuticals

                          Deal Size : $750.0 million

                          Deal Type : Acquisition

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : CMS will be responsible for developing and commercializing INCB54707, it is being evaluated for non-segmental vitiligo, hidradenitis suppurativa, prurigo nodularis, asthma.

                          Brand Name : INCB054707

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          April 01, 2024

                          Lead Product(s) : Povorcitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : China Medical System Holdings Limited

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          08

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : INCB54707 (povorcitinib) is an oral small-molecule JAK1 inhibitor currently in Phase 2 clinical trial for adult patients with prurigo nodularis. A Phase 3 trial is being planned for prurigo nodularis.

                          Brand Name : INCB054707

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 10, 2024

                          Lead Product(s) : Povorcitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Opzelura (ruxolitinib phosphate), a topical JAK1/JAK2 inhibitor, is in phase 2 trials for treating mild-to-moderate hidradenitis suppurativa in adults.

                          Brand Name : Opzelura

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 10, 2024

                          Lead Product(s) : Ruxolitinib Phosphate

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : INCA034176 (axatilimab) is an investigational monoclonal antibody that targets CSF-1R. It is bein evaluated for the treatment of chronic graft-versus-host disease.

                          Brand Name : INCA034176

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 27, 2024

                          Lead Product(s) : Axatilimab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Syndax Pharmaceuticals

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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