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Biosciences","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Buccal","sponsorNew":"Nona Biosciences \/ AbbVie Inc","highestDevelopmentStatusID":"2","companyTruncated":"Nona Biosciences \/ AbbVie Inc"},{"orgOrder":0,"company":"Altesa Biosciences","sponsor":"National Institutes of Health","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Discovery","graph3":"Altesa Biosciences","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Altesa Biosciences \/ National Institutes of Health","highestDevelopmentStatusID":"2","companyTruncated":"Altesa Biosciences \/ National Institutes of 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Find Novel Drugs for Infections and Infectious Diseases under Discovery

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Discovery

                          Sponsor : Kainomyx

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Details : Kainomyx has agreed to lead the technical strategy and associated aspects for drug discovery and clinical phases, Aurigene has agreed to focus on developing cost-effective and scalable drug chemistry.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          August 20, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Discovery

                          Sponsor : Kainomyx

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Aurigene

                          02

                          Details : The initial SARS-CoV-2 research program at Calibr, the drug discovery and development division of Scripps Research, was supported by funding from the Bill & Melinda Gates Foundation to deliver next generation oral antiviral treatments.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          March 15, 2022

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Discovery

                          Sponsor : Scripps Research

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

                          Abbvie Company Banner

                          03

                          Lead Product(s) : mRNA Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Discovery

                          Sponsor : Translate Bio

                          Deal Size : $2,300.0 million

                          Deal Type : Expanded Collaboration

                          Details : The two companies will build upon their existing collaboration to pursue novel mRNA vaccines aimed at broadly addressing current and future infectious diseases.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : $425.0 million

                          June 23, 2020

                          Lead Product(s) : mRNA Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Discovery

                          Sponsor : Translate Bio

                          Deal Size : $2,300.0 million

                          Deal Type : Expanded Collaboration

                          Sanofi Company Banner

                          04

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : The funding aims to advance company's novel anti-biofilm vaccine candidate, CMTX-301. It is being evaluated for the treatment of Bacterial Infections.

                          Product Name : CMTX-301

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          January 07, 2025

                          Lead Product(s) : CMTX-301

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Discovery

                          Sponsor : CARB-X

                          Deal Size : Undisclosed

                          Deal Type : Funding

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                          05

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : The proceeds will be used to advance babesiosis and tickborne disease research by addressing an underappreciated and understudied area of babesia biology and pathogenesis.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          October 30, 2024

                          Lead Product(s) : Babesia Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Discovery

                          Sponsor : NIAID

                          Deal Size : $0.1 million

                          Deal Type : Funding

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                          06

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : The agreement aims to develop small molecule broad-spectrum antiviral agents for the treatment of infections to improve the medical readiness of military personnel in biological threat environments.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          October 17, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Discovery

                          Sponsor : U.S. Department of Defense

                          Deal Size : $34.0 million

                          Deal Type : Agreement

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                          07

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : The net proceeds will be used for the lead optimization and candidate selection of a novel LA-injectable which targets malarial electron transport chain for malaria chemoprevention and prophylaxis.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          August 05, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Discovery

                          Sponsor : The Global Health Innovative Technology

                          Deal Size : $2.2 million

                          Deal Type : Funding

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                          08

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : The net proceeds will be used for the lead optimization of a novel and very promising T. cruzi active series being developed for the treatment of Chagas disease.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          August 05, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Discovery

                          Sponsor : The Global Health Innovative Technology

                          Deal Size : $1.9 million

                          Deal Type : Funding

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                          09

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : The net proceeds will be used to evaluate the safety and efficacy profiles of next-generation cPheRS-inhibitor antimalarials, with potentially lower cost of treatment and improved safety profiles.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          August 05, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Discovery

                          Sponsor : The Global Health Innovative Technology

                          Deal Size : $0.7 million

                          Deal Type : Funding

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                          10

                          CORTx

                          Country arrow
                          AAN
                          Not Confirmed

                          CORTx

                          Country arrow
                          AAN
                          Not Confirmed

                          Details :

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          July 29, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Discovery

                          Sponsor : MRFF

                          Deal Size : $4.0 million

                          Deal Type : Funding

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