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Partners"},{"orgOrder":0,"company":"Verrica Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Cantharidin","moa":"PP2A","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Verrica Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Topical Solution","sponsorNew":"Verrica Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Verrica Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Verrica Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Other Small 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Find Drugs for Infections and Infectious Diseases in Phase II Clinical Development

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                          01

                          Lead Product(s) : SARS-CoV-2 Recombinant Protein Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Phase II

                          Sponsor : GSK

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : The Phase 2 interim results of VAT00002 showed 95% to 100% seroconversion following a second injection in all age groups (18 to 95 years old) and across all doses, with acceptable tolerability and with no safety concerns.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          May 17, 2021

                          Lead Product(s) : SARS-CoV-2 Recombinant Protein Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : GSK

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          02

                          Lead Product(s) : Protein-Based COVID-19 Vaccine Recombinant, Adjuvant

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Phase II

                          Sponsor : GSK

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : The new Phase 2 trial is a randomized, double-blind, multi-center dose finding study conducted in adults aged 18 years of age and older to evaluate the safety, reactogenicity, and immunogenicity of two Adjuvanted recombinant protein-based COVID-19 vaccin...

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          February 22, 2021

                          Lead Product(s) : Protein-Based COVID-19 Vaccine Recombinant, Adjuvant

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : GSK

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          03

                          Lead Product(s) : Gam-COVID-Vac

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Dr Reddy's recently received permission from DCGI to conduct phase II and III trials of the Russian vaccine. If it receives an approval to continue, it will recruit 1,400 subjects for phase III.

                          Product Name : Sputnik V

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          October 28, 2020

                          Lead Product(s) : Gam-COVID-Vac

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Dr Reddy Company Banner

                          04

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : The financing aims to advance the clinical development of company's mid-stage product CRV-101 (amezosvatein). It is being evaluated to prevent shingles.

                          Product Name : CRV-101

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          March 17, 2025

                          Lead Product(s) : Amezosvatein

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Medicxi

                          Deal Size : $110.0 million

                          Deal Type : Series B Financing

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                          05

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : VH109, a CD4-binding broadly neutralising antibody, in combination with monthly cabotegravir long-acting (CAB LA), successfully kept viral levels suppressed in adults living with HIV.

                          Product Name : VH3810109

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          March 12, 2025

                          Lead Product(s) : VH109,Cabotegravir

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : VXA-CoV2-1 (SARS-CoV-2) next-generation bivalent norovirus vaccine, administered as orally, currently being investigated for the treatment of Covid-19.

                          Product Name : VXA-CoV2-1

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          March 11, 2025

                          Lead Product(s) : VXA-CoV2-1

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : VAX-31 is an PCV candidate, designed to prevent invasive pneumococcal disease, especially in infants, older adults & those with immune deficiencies or certain chronic health conditions.

                          Product Name : VAX-31

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          February 05, 2025

                          Lead Product(s) : 31-Valent Pneumococcal Conjugate Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : BIO 300 (genistein) is a DNA topoisomera II inhibitor administered as an oral suspension. It is being investigated for COVID-19 infection.

                          Product Name : BIO 300

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 22, 2025

                          Lead Product(s) : Genistein

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : CRV-101 (amezosvatein) uses an adjuvant targeting the TLR4 pathway to boost the immune response to the gE antigen. Currently being investigated for Shingles in 50 years and older.

                          Product Name : CRV-101

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          January 12, 2025

                          Lead Product(s) : Amezosvatein

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : CVXGA (CVXGA50) is the company’s PIV5-based intranasal vaccine candidate which is currently being evaluated for the treatment of COVID-19.

                          Product Name : CVXGA

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          December 09, 2024

                          Lead Product(s) : CVXGA

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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