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Molecule","year":"2021","type":"Agreement","leadProduct":"Opaganib","moa":"SPHK2","graph1":"Infections and Infectious Diseases","graph2":"Phase II\/ Phase III","graph3":"Cosmo Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Cosmo Pharmaceuticals \/ RedHill Biopharma","highestDevelopmentStatusID":"9","companyTruncated":"Cosmo Pharmaceuticals \/ RedHill Biopharma"},{"orgOrder":0,"company":"Serum Institute of India","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"INDIA","productType":"Vaccine","year":"2021","type":"Inapplicable","leadProduct":"Inactivated Salk Polio Vaccine","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase II\/ Phase III","graph3":"Serum Institute of India","amount2":0,"highestDevelopmentShortName":"Ph 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Inapplicable"},{"orgOrder":0,"company":"Abionyx Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"FRANCE","productType":"Protein","year":"2024","type":"Inapplicable","leadProduct":"CER-001","moa":"APOA-I","graph1":"Infections and Infectious Diseases","graph2":"Phase II\/ Phase III","graph3":"Abionyx Pharma","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Abionyx Pharma \/ Inapplicable","highestDevelopmentStatusID":"9","companyTruncated":"Abionyx Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Abionyx Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"FRANCE","productType":"Protein","year":"2023","type":"Inapplicable","leadProduct":"CER-001","moa":"APOA-I","graph1":"Infections and Infectious Diseases","graph2":"Phase 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Bpifrance"},{"orgOrder":0,"company":"Sanofi","sponsor":"DNDi","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"FRANCE","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Acoziborole","moa":"Protein Biosynthesis","graph1":"Infections and Infectious Diseases","graph2":"Phase II\/ Phase III","graph3":"Sanofi","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Sanofi \/ DNDi","highestDevelopmentStatusID":"9","companyTruncated":"Sanofi \/ DNDi"}]

Find Drugs for Infections and Infectious Diseases in Phase II/ Phase III Clinical Development

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01

Details : Under the partnership, Skyepharma will develop finished product batches meeting the GMP standards of Sarconeos (20-hydroxyecdysone), an orally administered small molecule, for severe forms of Covid-19.

Product Name : Sarconeos

Product Type : Other Small Molecule

Upfront Cash : Undisclosed

September 25, 2023

Lead Product(s) : 20-Hydroxyecdysone

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Phase II/ Phase III

Sponsor : Biophytis

Deal Size : Undisclosed

Deal Type : Partnership

Skyepharma Company Banner

02

Details : The agreement aims for the production of the active compound in Sarconeos (20-hydroxyecdysone), Biophytis' main drug candidate developed for three indications, severe forms of Covid-19, sarcopenia and Duchenne muscular dystrophy.

Product Name : Sarconeos

Product Type : Other Small Molecule

Upfront Cash : Undisclosed

July 18, 2023

Lead Product(s) : 20-Hydroxyecdysone

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Phase II/ Phase III

Sponsor : Biophytis

Deal Size : Undisclosed

Deal Type : Agreement

Seqens Company Banner

03

Details : Acoziborole, a potentially transformative investigational treatment for sleeping sickness, has a favourable safety profile, with no significant drug-related safety signals reported.

Product Name : SCYX-7158

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

November 30, 2022

Lead Product(s) : Acoziborole

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Phase II/ Phase III

Sponsor : DNDi

Deal Size : Inapplicable

Deal Type : Inapplicable

Sanofi Company Banner

04

Lead Product(s) : Sarilumab

Therapeutic Area : Infections and Infectious Diseases

Study Phase : Phase II/ Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : The US based trial will begin at medical centers in New York and will assess the safety and efficacy of adding Kevzara to usual supportive care, compared to supportive care plus placebo.

Product Name : Kevzara

Product Type : Antibody

Upfront Cash : Inapplicable

March 16, 2020

Lead Product(s) : Sarilumab

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Phase II/ Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Sanofi Company Banner

05

Lead Product(s) : Gam-COVID-Vac

Therapeutic Area : Infections and Infectious Diseases

Study Phase : Phase II/ Phase III

Sponsor : Russian Direct Investment Fund

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : After obtaining the requisite clearance from the Central Drugs Laboratory, Dr. Reddy's Laboratories and RDIF have begun adaptive phase 2/3 clinical trials for the Sputnik V vaccine in India. The trial is a multicenter and randomised controlled safety and...

Product Name : Sputnik V

Product Type : Vaccine

Upfront Cash : Inapplicable

January 12, 2020

Lead Product(s) : Gam-COVID-Vac

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Phase II/ Phase III

Sponsor : Russian Direct Investment Fund

Deal Size : Inapplicable

Deal Type : Inapplicable

Dr Reddy Company Banner

06

German Wound Congress
Not Confirmed
German Wound Congress
Not Confirmed

Details : The funding will be used for ABIONYX Pharma’s CER-001 Sepsis project. CER-001 is a negatively-charged lipoprotein particle which contains human recombinant apoA-I.

Product Name : CER-001

Product Type : Protein

Upfront Cash : Undisclosed

February 20, 2025

Lead Product(s) : CER-001

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Phase II/ Phase III

Sponsor : Bpifrance

Deal Size : $9.1 million

Deal Type : Funding

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07

German Wound Congress
Not Confirmed
German Wound Congress
Not Confirmed

Details : Under the agreement, GSK has the rights to develop GSK5458448/SCY-078 (ibrexafungerp), a novel oral glucan synthase inhibitor and commercialize Brexafemme in all countries except the greater China.

Product Name : Brexafemme

Product Type : Other Small Molecule

Upfront Cash : $90.0 million

July 23, 2024

Lead Product(s) : Ibrexafungerp Citrate

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Phase II/ Phase III

Sponsor : GSK

Deal Size : $593.0 million

Deal Type : Licensing Agreement

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08

German Wound Congress
Not Confirmed
German Wound Congress
Not Confirmed

Details : Merck is evaluating MK-1654 (clesrovimab), the company’s investigational prophylactic monoclonal antibody designed to protect infants from respiratory syncytial virus disease.

Product Name : MK-1654

Product Type : Antibody

Upfront Cash : Inapplicable

July 23, 2024

Lead Product(s) : Clesrovimab

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Phase II/ Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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09

German Wound Congress
Not Confirmed
German Wound Congress
Not Confirmed

Details : NVX-CoV2705 (JN.1 subvariant SARS CoV-2 rS vaccine) is an updated version of Novavax's prototype COVID-19 vaccine which is being evaluated in late stage clinical trials.

Product Name : Undisclosed

Product Type : Vaccine

Upfront Cash : Inapplicable

June 14, 2024

Lead Product(s) : JN.1 Subvariant SARS CoV-2 rS Vaccine

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Phase II/ Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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10

German Wound Congress
Not Confirmed
German Wound Congress
Not Confirmed

Details : Coartem® (artemether-lumefantrine) a novel formulation which is being developed forthe treatment of babies weighing less than 5kg with malaria.

Product Name : Coartem

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

April 23, 2024

Lead Product(s) : Artemether,Lumefantrine

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Phase II/ Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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