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    [{"orgOrder":0,"company":"Infinity Pharmaceuticals","sponsor":"BVF Partners L.P","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Financing","leadProduct":"Eganelisib","moa":"PI3K-gamma","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Infinity Pharmaceuticals","amount2":0.070000000000000007,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0.070000000000000007,"dosageForm":"Oral","sponsorNew":"Infinity Pharmaceuticals \/ BVF Partners L.P","highestDevelopmentStatusID":"8","companyTruncated":"Infinity Pharmaceuticals \/ BVF Partners L.P"},{"orgOrder":0,"company":"Infinity Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Eganelisib","moa":"PI3K gamma","graph1":"Oncology","graph2":"Phase 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molecule","year":"2023","type":"Termination","leadProduct":"Eganelisib","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Infinity Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Infinity Pharmaceuticals \/ MEI Pharma","highestDevelopmentStatusID":"8","companyTruncated":"Infinity Pharmaceuticals \/ MEI Pharma"}]

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                            01

                            Infinity Pharmaceuticals

                            U.S.A arrow
                            euroPLX 86 Munich
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                            Infinity Pharmaceuticals

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                            Lead Product(s) : Eganelisib,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : MEI Pharma

                            Deal Size : Undisclosed

                            Deal Type : Termination

                            DEALS_DEV arrow-down

                            Infinity Pharmaceuticals Announces Termination of Merger Agreement with MEI Pharma

                            Details : Under the termination, Infinity has continued to prepare for the initiation of a planned global Phase 2 clinical trial evaluating IPI-549 (eganelisib) in head and neck squamous cell carcinoma.

                            Brand Name : IPI-549

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            July 24, 2023

                            Lead Product(s) : Eganelisib,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : MEI Pharma

                            Deal Size : Undisclosed

                            Deal Type : Termination

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                            02

                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Infinity Pharmaceuticals

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                            Lead Product(s) : Eganelisib,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : MEI Pharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Infinity Pharmaceuticals Provides Additional Information on MARIO-8 Study Evaluating Eganelisib in Combination...

                            Details : IPI-549 (eganelisib) is a first-in-class, oral, once-daily, immuno-oncology candidate that selectively inhibits phosphoinositide-3-kinase gamma, which is investigated in Combination with Pembrolizumab in Patients with Squamous Cell Cancer of the Head and...

                            Brand Name : IPI-549

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 10, 2023

                            Lead Product(s) : Eganelisib,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : MEI Pharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Infinity Pharmaceuticals

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                            Lead Product(s) : Eganelisib,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : MEI Pharma

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            MEI Pharma and Infinity Pharmaceuticals Announce Definitive Merger Agreement to Advance Three Promising Clinic...

                            Details : The Combination will create a company with a diverse product development pipeline led by a planned new global Phase 2 clinical trial evaluating IPI-549 (eganelisib) in head and neck squamous cell carcinoma (HNSCC)

                            Brand Name : IPI-549

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            February 23, 2023

                            Lead Product(s) : Eganelisib,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : MEI Pharma

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            04

                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Infinity Pharmaceuticals Outlines Eganelisib Clinical Development Strategy and Provides 2022 Guidance

                            Details : IPI-54 (Eganelisb) in combination therapy has demonstrated positive resutls total tumor volume reduction is 92.8% and 85.2%, and disease control rates is 92.8% and 81.4%, in PD-L1 frontline TNBC patients.

                            Brand Name : IPI-549

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 05, 2022

                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Encouraging Updated Data from Phase 2 MARIO-3 TNBC Trial Presented at 2021 San Antonio Breast Cancer Symposium

                            Details : IPI-549 (eganelisib ), a first-in-class, oral, immuno-oncology macrophage reprogramming therapeutic addresses a fundamental biologic mechanism of immune suppression in cancer in multiple clinical studies.

                            Brand Name : IPI-549

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 10, 2021

                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Infinity Pharmaceuticals to Host an Investor Event on Updated MARIO-3 Data Presented at the 2021 San Antonio B...

                            Details : IPI-549 (eganelisib) immuno-oncology macrophage reprogramming therapeutic that selectively inhibits phosphoinositide-3-kinase gamma used as a frontline regimentriple negative breast cancer.

                            Brand Name : IPI-549

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 06, 2021

                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Infinity Pharmaceuticals Presents Updated Data from Phase 2 MARIO-275 Trial

                            Details : At the one-year landmark, 59% of patients in the ITT population receiving the eganelisib plus nivolumab combination remained alive, compared to 32% in the nivolumab control arm.

                            Brand Name : IPI-549

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 27, 2021

                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Infinity Pharmaceuticals Hosting Webinar on MARIO-3 and MARIO-275 Phase 2 Trials

                            Details : MARIO-3 is a Phase 2 triplet combination study evaluating the addition of eganelisib to the approved standard of care combination of Tecentriq® and Abraxane® in the front-line setting in TNBC.

                            Brand Name : IPI-549

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 20, 2021

                            Lead Product(s) : Eganelisib,Atezolizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Infinity Pharmaceuticals

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                            euroPLX 86 Munich
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                            Lead Product(s) : Eganelisib,Nivolumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Arcus Biosciences

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Infinity to Present at The Keystone Symposia Precision Oncology Meeting

                            Details : In collaboration with Arcus Biosciences, Infinity is evaluating a checkpoint inhibitor-free, novel combination regimen of eganelisib plus etrumadenant (AB928, a dual adenosine receptor antagonist) plus Doxil® in advanced TNBC patients.

                            Brand Name : IPI-549

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 14, 2021

                            Lead Product(s) : Eganelisib,Nivolumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Arcus Biosciences

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Infinity Pharmaceuticals

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed

                            Infinity Pharmaceuticals

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : Eganelisib,Etrumadenant

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Arcus Biosciences

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Infinity to Present at New York Academy of Sciences’ Frontiers in Cancer Immunotherapy 2021

                            Details : The Phase 1b clinical trial is a global multi-center, open-label trial of CERC-007 that will enroll around 12 subjects with active adult onset Still’s disease with a primal goal of the study will be to determine the safety and tolerability of CERC-007 ...

                            Brand Name : IPI-549

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 05, 2021

                            Lead Product(s) : Eganelisib,Etrumadenant

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Arcus Biosciences

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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