Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : SAR447537
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Sanofi
Deal Size : $2,196.0 million
Deal Type : Acquisition
Sanofi Completes Acquisition of Inhibrx, Inc.
Details : Sanofi will acquire all the assets and liabilities associated with INBRX-101, a recombinant alpha-1 antitrypsin augmentation therapy currently in a trial for alpha-1 antitrypsin deficiency.
Product Name : INBRX-101
Product Type : Large molecule
Upfront Cash : $2,196.0 million
May 30, 2024
Lead Product(s) : SAR447537
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Sanofi
Deal Size : $2,196.0 million
Deal Type : Acquisition
Lead Product(s) : INBRX-101
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Sanofi
Deal Size : $2,196.0 million
Deal Type : Acquisition
Inhibrx Announces Sale of INBRX-101 to Sanofi for an Aggregate Value of up to $2.2 B
Details : Sanofi will acquire assets and liabilities of INBRX-101, a recombinant alpha-1 antitrypsin augmentation therapy in a registrational trial for alpha-1 antitrypsin deficiency.
Product Name : INBRX-101
Product Type : Large molecule
Upfront Cash : $2,196.0 million
January 22, 2024
Lead Product(s) : INBRX-101
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Sanofi
Deal Size : $2,196.0 million
Deal Type : Acquisition
Lead Product(s) : INBRX-105,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Sanofi
Deal Size : $200.0 million
Deal Type : Demerger
Inhibrx Announces Sale of INBRX-101 to Sanofi for an Aggregate Value of up to $2.2 B
Details : Under the agreement, non-101 assets, like INBRX-105, INBRX-106, and INBRX-109, will be spun out into a new publicly traded company, Inhibrx Biosciences, separate from the original Company.
Product Name : INBRX-105
Product Type : Large molecule
Upfront Cash : $200.0 million
January 22, 2024
Lead Product(s) : INBRX-105,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Sanofi
Deal Size : $200.0 million
Deal Type : Demerger
Lead Product(s) : INBRX-109,Temozolomide,Irinotecan Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : INBRX-109 is a precision-engineered, tetravalent death receptor 5 (DR5) agonist antibody designed to exploit the tumor-biased cell death induced by DR5 activation, which is investigated for Ewing sarcoma.
Product Name : INBRX-109
Product Type : Large molecule
Upfront Cash : Not Applicable
November 02, 2023
Lead Product(s) : INBRX-109,Temozolomide,Irinotecan Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : INBRX-101
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : INBRX-101 is a precisely engineered recombinant human AAT-Fc fusion protein designed to safely achieve and maintain levels of Alpha-1 Antitrypsin Deficiency and received Fast Track Designation.
Product Name : INBRX-101
Product Type : Large molecule
Upfront Cash : Not Applicable
May 30, 2023
Lead Product(s) : INBRX-101
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : rhAAT-Fc
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : INBRX-101 is a precisely engineered recombinant human AAT-Fc fusion protein designed to safely achieve and maintain levels of alpha-1 antitrypsin (AAT) in patients with emphysema due to alpha-1 antitrypsin deficiency (AATD).
Product Name : INBRX-101
Product Type : Large molecule
Upfront Cash : Not Applicable
April 26, 2023
Lead Product(s) : rhAAT-Fc
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Actinium-225 Conjugated Therapy
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : NorthStar Medical Radioisotopes
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under this agreement with Inhibrx, NorthStar will support the development of a prespecified number of Inhibrx’s novel biologic products by providing the Ac-225 supply for the Actinium-225 Conjugated Therapy and access to its integrated radiopharmaceuti...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
January 04, 2023
Lead Product(s) : Actinium-225 Conjugated Therapy
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : NorthStar Medical Radioisotopes
Deal Size : Undisclosed
Deal Type : Collaboration
Details : INBRX-109 is a precision-engineered, tetravalent DR5 agonist antibody designed to exploit the tumor-biased cell death induced by DR5 activation being developed for the treatment of patients with unresectable or metastatic conventional chondrosarcoma and ...
Product Name : INBRX-109
Product Type : Large molecule
Upfront Cash : Not Applicable
November 16, 2022
Lead Product(s) : rhAAT-Fc
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : INBRX-101 is precisely engineered recombinant human AAT-Fc fusion protein designed to safely achieve and maintain levels of alpha-1 antitrypsin found in healthy individuals with dosing interval compared to weekly infusion interval plasma-derived AAT ther...
Product Name : INBRX-101
Product Type : Large molecule
Upfront Cash : Not Applicable
October 04, 2022
Lead Product(s) : rhAAT-Fc
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : rhAAT-Fc
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : INBRX-101 (rhAAT-Fc) is precisely engineered fusion protein designed to safely achieve and maintain levels of alpha-1 antitrypsin, or AAT, found healthy individuals with less frequent dosing interval compared weekly infusion interval of available plasma-...
Product Name : INBRX-101
Product Type : Large molecule
Upfront Cash : Not Applicable
October 03, 2022
Lead Product(s) : rhAAT-Fc
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable