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    [{"orgOrder":0,"company":"Inmagene Biopharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Antibody","year":"2023","type":"Inapplicable","leadProduct":"IMG-007","moa":"OX40 receptor","graph1":"Dermatology","graph2":"Phase I\/ Phase II","graph3":"Inmagene Biopharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Inmagene Biopharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Inmagene Biopharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Inmagene Biopharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody","year":"2023","type":"Inapplicable","leadProduct":"IMG-008","moa":"IL-36 receptor","graph1":"Immunology","graph2":"IND Enabling","graph3":"Inmagene 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Inapplicable"},{"orgOrder":0,"company":"Inmagene Biopharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Antibody","year":"2025","type":"Inapplicable","leadProduct":"IMG-007","moa":"OX40 receptor","graph1":"Dermatology","graph2":"Phase I\/ Phase II","graph3":"Inmagene Biopharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Inmagene Biopharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Inmagene Biopharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Inmagene Biopharmaceuticals","sponsor":"Hutchmed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody","year":"2021","type":"Inapplicable","leadProduct":"IMG-007","moa":"OX40 receptor","graph1":"Immunology","graph2":"Preclinical","graph3":"Inmagene Biopharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Inmagene Biopharmaceuticals \/ Hutchmed","highestDevelopmentStatusID":"4","companyTruncated":"Inmagene Biopharmaceuticals \/ Hutchmed"},{"orgOrder":0,"company":"Inmagene Biopharmaceuticals","sponsor":"Hutchmed","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"IMG-004","moa":"BTK","graph1":"Neurology","graph2":"Phase I","graph3":"Inmagene Biopharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Inmagene Biopharmaceuticals \/ Hutchmed","highestDevelopmentStatusID":"6","companyTruncated":"Inmagene Biopharmaceuticals \/ Hutchmed"},{"orgOrder":0,"company":"Inmagene 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I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Inmagene Biopharmaceuticals \/ Hutchmed","highestDevelopmentStatusID":"6","companyTruncated":"Inmagene Biopharmaceuticals \/ Hutchmed"},{"orgOrder":0,"company":"Inmagene Biopharmaceuticals","sponsor":"Vertex Ventures","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Protein","year":"2020","type":"Series B Financing","leadProduct":"IMG-20","moa":"IL-17A receptor","graph1":"Dermatology","graph2":"Phase II","graph3":"Inmagene Biopharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Inmagene Biopharmaceuticals \/ Vertex Ventures","highestDevelopmentStatusID":"8","companyTruncated":"Inmagene Biopharmaceuticals \/ Vertex Ventures"},{"orgOrder":0,"company":"Inmagene Biopharmaceuticals","sponsor":"Affibody","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Protein","year":"2021","type":"Inapplicable","leadProduct":"Izokibep","moa":"IL-17A receptor","graph1":"Immunology","graph2":"Phase II","graph3":"Inmagene Biopharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Inmagene Biopharmaceuticals \/ Affibody","highestDevelopmentStatusID":"8","companyTruncated":"Inmagene Biopharmaceuticals \/ Affibody"},{"orgOrder":0,"company":"Inmagene Biopharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Antibody","year":"2025","type":"Inapplicable","leadProduct":"IMG-007","moa":"OX40 receptor","graph1":"Dermatology","graph2":"Phase I\/ Phase II","graph3":"Inmagene Biopharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Inmagene Biopharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Inmagene Biopharmaceuticals \/ Inapplicable"}]

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                            01

                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Inmagene Biopharmaceuticals

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                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Inmagene Reports Positive Phase 2a Alopecia Areata Results with IMG-007

                            Details : IMG-007 is a monoclonal antibody (mAb) targeting OX40, currently being investigated for the treatment of alopecia areata.

                            Product Name : IMG-007

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            April 24, 2025

                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Inmagene Reports Positive Topline Results of IMG-007 for Atopic Dermatitis

                            Details : IMG-007 is a monoclonal antibody (mAb) targeting OX40, currently being investigated for the treatment of atopic dermatitis.

                            Product Name : IMG-007

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            January 09, 2025

                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Ikena Oncology

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Ikena and Inmagene Announce Merger and Private Placement Agreement

                            Details : Through the merger, the combined company will prioritize the development of IMG-007, a monoclonal antibody (mAb) targeting OX40, for the treatment of atopic dermatitis.

                            Product Name : IMG-007

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            December 23, 2024

                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Ikena Oncology

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            04

                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Lead Product(s) : IMG-004

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Inmagene Announces Positive Results from IMG-004 Multiple Ascending Dose Study

                            Details : IMG-004 is a potent, non-covalent, brain permeable BTK inhibitor, being evaluated as an oral, once daily formulation for the treatment of chronic spontaneous urticaria and hidradenitis suppurativa.

                            Product Name : IMG-004

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 27, 2024

                            Lead Product(s) : IMG-004

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Inmagene Reports Positive Results from Phase 2a Trial of IMG-007 for Atopic Dermatitis

                            Details : IMG-007 is a humanized anti-OX40 IgG1 mAb, with a silenced ADCC function and an extended half-life. It is designed to target immunological diseases like atopic dermatitis.

                            Product Name : IMG-007

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            June 05, 2024

                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Inmagene Doses First Patient in Phase 2a Trial of IMG-007, an Anti-OX40 Monoclonal Antibody with an Extended H...

                            Details : IMG-007 is a humanized IgG1 mAb that specifically binds to the OX40 receptor and potently blocks the signaling between OX40 and its ligand, being evaluated for the treatment of alopecia areata (AA) and atopic dermatitis (AD).

                            Product Name : IMG-007

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            October 13, 2023

                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Inmagene Biopharmaceuticals

                            U.S.A arrow
                            AACR Annual meeting
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                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
                            Not Confirmed
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                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Inmagene's anti-OX40 mAb Demonstrated an Extended Half-life And a Favorable Safety Profile in a Phase I study

                            Details : IMG-007 is a humanized IgG1 mAb that specially binds to the OX40 receptor with high affinity and is being investigated for the treatment of moderate-to-severe atopic dermatitis.

                            Product Name : IMG-007

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            August 18, 2023

                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Inmagene Biopharmaceuticals

                            U.S.A arrow
                            AACR Annual meeting
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                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Inmagene's OX40 mAb, with an Extended Half-life and Silenced ADCC, Enters POC Study in Atopic Dermatitis

                            Details : IMG-007 is a humanized IgG1 monoclonal antibody that specifically binds to the OX40 receptor, which is investigated for the adult patients with moderate-to-severe atopic dermatitis.

                            Product Name : IMG-007

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            August 15, 2023

                            Lead Product(s) : IMG-007

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Lead Product(s) : IMG-008

                            Therapeutic Area : Immunology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Inmagene Receives IND Clearance For IMG-008, A Long-Acting IL-36R mAb

                            Details : IMG-008 is a novel long-acting antagonistic monoclonal antibody having high binding affinity to IL-36R and has potent in vitro activity to block IL-36R downstream signaling and cytokine release. It is being developed to potentially treat auto-inflammator...

                            Product Name : IMG-008

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            June 02, 2023

                            Lead Product(s) : IMG-008

                            Therapeutic Area : Immunology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Inmagene Biopharmaceuticals

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                            AACR Annual meeting
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                            Lead Product(s) : IMG-004

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Hutchmed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            IMG-004 Demonstrated Extended Half-Life and Durable Pharmacodynamic Characteristics in A Phase 1 Study

                            Details : IMG-004 is a potent, non-covalent, reversible, and brain permeable third-generation Bruton's tyrosine kinase (BTK) inhibitor. It is being developed as a potential treat immunological diseases.

                            Product Name : IMG-004

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 28, 2023

                            Lead Product(s) : IMG-004

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Hutchmed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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