Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : IMG-007
Therapeutic Area : Dermatology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Inmagene Reports Positive Topline Results of IMG-007 for Atopic Dermatitis
Details : IMG-007 is a monoclonal antibody (mAb) targeting OX40, currently being investigated for the treatment of atopic dermatitis.
Product Name : IMG-007
Product Type : Antibody
Upfront Cash : Inapplicable
January 09, 2025
Lead Product(s) : IMG-007
Therapeutic Area : Dermatology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : IMG-007
Therapeutic Area : Dermatology
Study Phase : Phase I/ Phase II
Sponsor : Ikena Oncology
Deal Size : Undisclosed
Deal Type : Merger
Ikena and Inmagene Announce Merger and Private Placement Agreement
Details : Through the merger, the combined company will prioritize the development of IMG-007, a monoclonal antibody (mAb) targeting OX40, for the treatment of atopic dermatitis.
Product Name : IMG-007
Product Type : Antibody
Upfront Cash : Undisclosed
December 23, 2024
Lead Product(s) : IMG-007
Therapeutic Area : Dermatology
Highest Development Status : Phase I/ Phase II
Sponsor : Ikena Oncology
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : IMG-004
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Inmagene Announces Positive Results from IMG-004 Multiple Ascending Dose Study
Details : IMG-004 is a potent, non-covalent, brain permeable BTK inhibitor, being evaluated as an oral, once daily formulation for the treatment of chronic spontaneous urticaria and hidradenitis suppurativa.
Product Name : IMG-004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 27, 2024
Lead Product(s) : IMG-004
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : IMG-007
Therapeutic Area : Dermatology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Inmagene Reports Positive Results from Phase 2a Trial of IMG-007 for Atopic Dermatitis
Details : IMG-007 is a humanized anti-OX40 IgG1 mAb, with a silenced ADCC function and an extended half-life. It is designed to target immunological diseases like atopic dermatitis.
Product Name : IMG-007
Product Type : Antibody
Upfront Cash : Inapplicable
June 05, 2024
Lead Product(s) : IMG-007
Therapeutic Area : Dermatology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : IMG-007
Therapeutic Area : Dermatology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IMG-007 is a humanized IgG1 mAb that specifically binds to the OX40 receptor and potently blocks the signaling between OX40 and its ligand, being evaluated for the treatment of alopecia areata (AA) and atopic dermatitis (AD).
Product Name : IMG-007
Product Type : Antibody
Upfront Cash : Inapplicable
October 13, 2023
Lead Product(s) : IMG-007
Therapeutic Area : Dermatology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : IMG-007
Therapeutic Area : Dermatology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IMG-007 is a humanized IgG1 mAb that specially binds to the OX40 receptor with high affinity and is being investigated for the treatment of moderate-to-severe atopic dermatitis.
Product Name : IMG-007
Product Type : Antibody
Upfront Cash : Inapplicable
August 18, 2023
Lead Product(s) : IMG-007
Therapeutic Area : Dermatology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : IMG-007
Therapeutic Area : Dermatology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IMG-007 is a humanized IgG1 monoclonal antibody that specifically binds to the OX40 receptor, which is investigated for the adult patients with moderate-to-severe atopic dermatitis.
Product Name : IMG-007
Product Type : Antibody
Upfront Cash : Inapplicable
August 15, 2023
Lead Product(s) : IMG-007
Therapeutic Area : Dermatology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : IMG-008
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Inmagene Receives IND Clearance For IMG-008, A Long-Acting IL-36R mAb
Details : IMG-008 is a novel long-acting antagonistic monoclonal antibody having high binding affinity to IL-36R and has potent in vitro activity to block IL-36R downstream signaling and cytokine release. It is being developed to potentially treat auto-inflammator...
Product Name : IMG-008
Product Type : Antibody
Upfront Cash : Inapplicable
June 02, 2023
Lead Product(s) : IMG-008
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IMG-004 is a potent, non-covalent, reversible, and brain permeable third-generation Bruton's tyrosine kinase (BTK) inhibitor. It is being developed as a potential treat immunological diseases.
Product Name : IMG-004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 28, 2023
Inmagene and HUTCHMED Announce First Participants in Global Phase I Trial of IMG-004
Details : IMG-004 is a non-covalent, reversible small molecule inhibitor targeting BTK. Designed specifically for inflammatory and autoimmune diseases that usually require long-term treatment, IMG-004 is potent, highly selective and brain permeable.
Product Name : IMG-004
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 08, 2022