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    [{"orgOrder":0,"company":"Intensity Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Cisplatin","moa":"DNA","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Intensity Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intratumoral Injection","sponsorNew":"Intensity Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Intensity Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Intensity Therapeutics","sponsor":"Bristol Myers Squibb","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Collaboration","leadProduct":"Cisplatin","moa":"DNA","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Intensity 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    Find Clinical Drug Pipeline Developments & Deals by Intensity Therapeutics

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                            01

                            Intensity Therapeutics

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                            Intensity Therapeutics

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                            Lead Product(s) : Vinblastine Sulfate,Cisplatin,2-hydroxybenzoyl Amino Octanoate

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : SAKK

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Intensity Therapeutics, Sakk Ink Agreement for Phase 2 Trial in Early-Stage Cancer

                            Details : The collaboration aims to conduct a phase 2 trial evaluating the clinical and biological effects of intratumoral INT230-6 in early-stage triple-negative breast cancer.

                            Brand Name : INT230-6

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            May 13, 2024

                            Lead Product(s) : Vinblastine Sulfate,Cisplatin,2-hydroxybenzoyl Amino Octanoate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : SAKK

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            02

                            Intensity Therapeutics

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                            Intensity Therapeutics

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                            Lead Product(s) : 2-hydroxybenzoyl Amino Octanoate,Vinblastine Sulfate,Cisplatin

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : The Benchmark Company

                            Deal Size : $19.5 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Intensity Therapeutics, Inc. Announces Pricing of Upsized Initial Public Offering, Raising Approximately $19.5...

                            Details : The company intends to use the net proceeds for the development of INT230-6, a formulation consisting of its proprietary amphiphilic cell penetration enhancer molecule, 8-((2-hydroxybenzoyl)amino)octanoate, also referred to as SHAO, combined with cisplat...

                            Brand Name : INT230-6

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 30, 2023

                            Lead Product(s) : 2-hydroxybenzoyl Amino Octanoate,Vinblastine Sulfate,Cisplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : The Benchmark Company

                            Deal Size : $19.5 million

                            Deal Type : Public Offering

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                            03

                            Intensity Therapeutics

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                            Lead Product(s) : Cisplatin,Vinblastine Sulfate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Intensity Therapeutics Reports Use of INT230-6 Alone or in Combination with Ipilimumab Shows Evidence of Direc...

                            Details : INT230-6 is designed for direct intratumoral injection, composed of two proven, potent anti-cancer agent, cisplatin and vinblastine, and penetration enhancer molecule that help disperse potent cytotoxic drugs throughout tumors for diffusion into cancer c...

                            Brand Name : INT230-6

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 18, 2022

                            Lead Product(s) : Cisplatin,Vinblastine Sulfate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Intensity Therapeutics

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                            Intensity Therapeutics

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                            Lead Product(s) : IMM60,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Portage Biotech

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Portage Biotech Summarizes Data Presented at ASCO 2022 Annual Meeting Including Updates from Ongoing PORT-2 St...

                            Details : Translational analysis of IMM60 confirms that PORT-2 activates iNKT cells, NK cells and dendritic cells, supporting the mechanism of action to stimulate both the adaptive and innate immune system.

                            Brand Name : IMM60

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 06, 2022

                            Lead Product(s) : IMM60,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Portage Biotech

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Intensity Therapeutics

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                            Lead Product(s) : Cisplatin,Vinblastine Sulfate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Intensity Therapeutics' INT230-6 Demonstrates Increased Survival as Either Monotherapy or in Combination with ...

                            Details : Data show INT230-6 (Cisplatin), is designed for direct intratumoral injection is well tolerated and elicits both direct tumor killing and immune activating effects in a variety of solid tumors.

                            Brand Name : INT230-6

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 03, 2022

                            Lead Product(s) : Cisplatin,Vinblastine Sulfate,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Intensity Therapeutics

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                            Lead Product(s) : INT230-6

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Intensity Therapeutics' Data on Lead Asset, INT230-6, Accepted for Presentation at Two Major Scientific Clinic...

                            Details : INT230-6, Intensity’s lead proprietary investigational product candidate, is designed for direct intratumoral injection was discovered using Intensity’s proprietary DfuseRx℠ technology platform.

                            Brand Name : INT230-6

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 03, 2021

                            Lead Product(s) : INT230-6

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Intensity Therapeutics

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                            Intensity Therapeutics

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                            Lead Product(s) : Cisplatin,Vinblastine Sulfate,Ipilimumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Intensity Therapeutics’ INT230-6 Effective as Either Monotherapy or in Combination with Checkpoint Inhibitor...

                            Details : Data in the first poster show that INT230-6, monotherapy or in combination with pembrolizumab, is well tolerated and elicits both direct tumor killing and abscopal effects. The second presentation reports similar results of INT230-6 with or without ipili...

                            Brand Name : INT230-6

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 02, 2021

                            Lead Product(s) : Cisplatin,Vinblastine Sulfate,Ipilimumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Intensity Therapeutics

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                            Lead Product(s) : Cisplatin,Vinblastine Sulfate,Salcaprozate Sodium

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Ottawa Hospital

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Intensity Therapeutics, The Ottawa Hospital and The Ontario Institute for Cancer Research Sign Agreements

                            Details : The Ottawa Hospital and The Ontario Institute for Cancer Research (OICR) to conduct a Phase II Randomized, Window of Opportunity (WOO) trial evaluating clinical and biological effects of intratumoral INT230-6 vs. no treatment in early stage breast cancer...

                            Brand Name : INT230-6

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            March 24, 2021

                            Lead Product(s) : Cisplatin,Vinblastine Sulfate,Salcaprozate Sodium

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Ottawa Hospital

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            09

                            Intensity Therapeutics

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                            Lead Product(s) : Cisplatin,Vinblastine Sulfate,Ipilimumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Intensity Therapeutics Reports Favorable Data of INT230-6 from the Ongoing Phase 1/2 Study in Patients with Ad...

                            Details : Local delivery of INT230-6 as monotherapy into tumors induced an immune response with increases of activated CD4+ and CD8+ T-cells in the tumor without any immune-related adverse events.

                            Brand Name : INT230-6

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 11, 2020

                            Lead Product(s) : Cisplatin,Vinblastine Sulfate,Ipilimumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Intensity Therapeutics

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                            Lead Product(s) : Cisplatin,Vinblastine Sulfate,Ipilimumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Intensity Therapeutics Doses First Patient with Combination of INT230-6 and Bristol Myers Squibb’s Yervoy® ...

                            Details : The scPharmaceuticals management team will discuss the FUROSCIX® development plan. FUROSCIX® is an investigational, proprietary formulation of furosemide that is administered subcutaneously via a wearable on-body, drug delivery system, for outpatient s...

                            Brand Name : INT230-6

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 17, 2020

                            Lead Product(s) : Cisplatin,Vinblastine Sulfate,Ipilimumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Bristol Myers Squibb

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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