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    [{"orgOrder":0,"company":"Intra-Cellular Therapies","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Lumateperone Tosylate","moa":"5-HT2A receptor","graph1":"Psychiatry\/Psychology","graph2":"Approved","graph3":"Intra-Cellular Therapies","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Intra-Cellular Therapies \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Intra-Cellular Therapies \/ Not Applicable"},{"orgOrder":0,"company":"Intra-Cellular Therapies","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"ITI214","moa":"PDE1","graph1":"Cardiology\/Vascular 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    Find Clinical Drug Pipeline Developments & Deals by Intra-Cellular Therapies

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                            01

                            Intra-Cellular Therapies

                            U.S.A arrow
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                            Intra-Cellular Therapies

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                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Intra-Cellular Reports Positive CAPLYTA Results for Schizophrenia Relapse Prevention

                            Details : Caplyta (lumateperone) is an oral, once daily atypical antipsychotic that acts as a 5-HT2A & D2 receptor antagonist. It is being evaluated for relapse in adult patients with schizophrenia.

                            Brand Name : Caplyta

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 05, 2024

                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Intra-Cellular Therapies

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                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Intra-Cellular Therapies Reports Positive Phase 3 Results for Lumateperone in Depression

                            Details : Caplyta (lumateperone) is an oral, once daily atypical antipsychotic that acts as a 5-HT2A & D2 receptor antagonist. It is being evaluated for the treatment of major depressive disorder.

                            Brand Name : Caplyta

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 18, 2024

                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Intra-Cellular Therapies

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                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Approved

                            Sponsor : J.P. Morgan

                            Deal Size : $575.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Intra-Cellular Closes $575 Million Public Offering Including Underwriters' Option

                            Details : The intend to use the net proceeds from this offering to fund commercialization activities of Caplyta (lumateperone), which is indicated for the treatment of schizophrenia.

                            Brand Name : Caplyta

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            April 24, 2024

                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Approved

                            Sponsor : J.P. Morgan

                            Deal Size : $575.0 million

                            Deal Type : Public Offering

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                            04

                            Intra-Cellular Therapies

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                            Intra-Cellular Therapies

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                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Approved

                            Sponsor : J.P. Morgan

                            Deal Size : $500.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Intra-Cellular Therapies Prices Public Offering of Common Stock

                            Details : Caplyta (lumateperone) proceeds will support continued commercialization in treating schizophrenia and bipolar depression.

                            Brand Name : Caplyta

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            April 17, 2024

                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Approved

                            Sponsor : J.P. Morgan

                            Deal Size : $500.0 million

                            Deal Type : Public Offering

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                            05

                            Intra-Cellular Therapies

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                            Pharmtech & Ingredients
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                            Intra-Cellular Therapies

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                            Pharmtech & Ingredients
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                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Approved

                            Sponsor : J.P. Morgan

                            Deal Size : $500.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Intra-Cellular Therapies Announces Proposed Public Offering of Common Stock

                            Details : Caplyta (lumateperone) proceeds will support commercialization activities for its use in schizophrenia and bipolar depression treatment.

                            Brand Name : Caplyta

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            April 16, 2024

                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Approved

                            Sponsor : J.P. Morgan

                            Deal Size : $500.0 million

                            Deal Type : Public Offering

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                            06

                            Intra-Cellular Therapies

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                            Intra-Cellular Therapies

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                            Pharmtech & Ingredients
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                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Intra-Cellular Announces Positive Phase 3 Results for Lumateperone in Depression

                            Details : Caplyta (lumateperone) is an oral, once daily atypical antipsychotic that acts as a 5-HT2A & D2 receptor antagonist. It is being evaluated for the treatment of major depressive disorder.

                            Brand Name : Caplyta

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 16, 2024

                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Intra-Cellular Therapies

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                            Pharmtech & Ingredients
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                            Intra-Cellular Therapies

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                            Pharmtech & Ingredients
                            Not Confirmed
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                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Intra-Cellular Therapies Announces CAPLYTA Data Presentations at the American Society of Clinical Psychopharma...

                            Details : Caplyta® (lumateperone) has a combination mechanism of antagonist activity at central serotonin 5-HT2A receptors and postsynaptic antagonist activity at central dopamine D2 receptors. It is investigated for the treatment of bipolar I or bipolar II disor...

                            Brand Name : Caplyta

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 31, 2023

                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Intra-Cellular Therapies

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                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Intra-Cellular Therapies Announces Positive Topline Results from Study 403 Evaluating Lumateperone as Monother...

                            Details : Caplyta® (lumateperone) has a combination mechanism of antagonist activity at central serotonin 5-HT2A receptors and postsynaptic antagonist activity at central dopamine D2 receptors. It is used for the treatment of major depressive disorers.

                            Brand Name : Caplyta

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 28, 2023

                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Intra-Cellular Therapies

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                            Pharmtech & Ingredients
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                            Intra-Cellular Therapies

                            U.S.A arrow
                            Pharmtech & Ingredients
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Intra-Cellular Therapies Highlights New CAPLYTA Bipolar Depression Data Presentations at the American College ...

                            Details : The results confirm the favorable effects of Caplyta (lumateperone) 42mg on body weight and morphology as demonstrated by minimal and similar to placebo mean changes from baseline in weight, BMI (kg/m2) and waist circumference in short-term studies.

                            Brand Name : Caplyta

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 08, 2022

                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Intra-Cellular Therapies

                            U.S.A arrow
                            Pharmtech & Ingredients
                            Not Confirmed

                            Intra-Cellular Therapies

                            U.S.A arrow
                            Pharmtech & Ingredients
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Intra-Cellular Therapies Highlights Lumateperone Bipolar Depression Data Presentations at the 2022 Internation...

                            Details : Caplyta (lumateperone) has a combination mechanism of antagonist activity at central serotonin 5-HT2A receptors and postsynaptic antagonist activity at central D2 receptors. It is investigated for major depressive episodes associated with bipolar I or II...

                            Brand Name : Caplyta

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 13, 2022

                            Lead Product(s) : Lumateperone Tosylate

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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