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    [{"orgOrder":0,"company":"Invios","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2021","type":"Not Applicable","leadProduct":"APN401","moa":"Cbl-b","graph1":"Oncology","graph2":"Phase I","graph3":"Invios","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"Invios \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Invios \/ Not Applicable"},{"orgOrder":0,"company":"Invios","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"siRNA-transfected Peripheral Blood Mononuclear Cells","moa":"Cbl-b","graph1":"Oncology","graph2":"Phase I","graph3":"Invios","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Invios \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Invios \/ Not Applicable"},{"orgOrder":0,"company":"Invios","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"INV501","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Invios","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Invios \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Invios \/ Not Applicable"},{"orgOrder":0,"company":"Invios","sponsor":"Austrian Research Promotion Agency","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2023","type":"Funding","leadProduct":"APN401","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Invios","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Invios \/ Austrian Research Promotion Agency","highestDevelopmentStatusID":"6","companyTruncated":"Invios \/ Austrian Research Promotion Agency"},{"orgOrder":0,"company":"Invios","sponsor":"Dana-Farber Cancer Institute","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Collaboration","leadProduct":"INV501","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Invios","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Invios \/ Dana-Farber Cancer Institute","highestDevelopmentStatusID":"4","companyTruncated":"Invios \/ Dana-Farber Cancer Institute"},{"orgOrder":0,"company":"Invios","sponsor":"Ligand Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Series A Financing","leadProduct":"INV501","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Invios","amount2":0.01,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Invios \/ Ligand Pharmaceuticals","highestDevelopmentStatusID":"14","companyTruncated":"Invios \/ Ligand Pharmaceuticals"}]

    Find Clinical Drug Pipeline Developments & Deals by Invios

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                            Invios

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                            Lead Product(s) : INV501

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Ligand Pharmaceuticals

                            Deal Size : $8.8 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Invios Raises €8.2 Million in a Series A to Finance Pipeline Progress in Immuno-Oncology

                            Details : The net proceeds will secure ongoing pipeline progress, including INV501, a first-in-class orally available small molecule that can selectively enhance T cell mediated anti-tumor immune responses.

                            Brand Name : INV501

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 15, 2024

                            Lead Product(s) : INV501

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Ligand Pharmaceuticals

                            Deal Size : $8.8 million

                            Deal Type : Series A Financing

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                            Lead Product(s) : INV501

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Dana-Farber Cancer Institute

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            invIOs and Dana-Farber Cancer Institute Start Collaboration to Study Novel Small Molecule INV501 for Treatment...

                            Details : The collaboration aims to evaluate invIOs’ small molecule INV501 that can selectively enhance anti-tumor immune responses, as a potential treatment for glioblastoma.

                            Brand Name : INV501

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            November 09, 2023

                            Lead Product(s) : INV501

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Dana-Farber Cancer Institute

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Lead Product(s) : APN401

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Austrian Research Promotion Agency

                            Deal Size : Undisclosed

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            invIOs Starts Further Clinical Trial of APN401, Novel Cell Therapy Against Solid Cancers, and Secures Major Au...

                            Details : The funding will be used for a Phase 1b trial of its novel autologous cell therapy, APN401, an innovative approach that leverages invIOs’s proprietary EPiC cell therapy platform, in patients with solid tumors.

                            Brand Name : APN401

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 06, 2023

                            Lead Product(s) : APN401

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Austrian Research Promotion Agency

                            Deal Size : Undisclosed

                            Deal Type : Funding

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                            Lead Product(s) : INV501

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            invIOs Presents Exciting Preclinical Data Showing that Immune-Activating Small Molecule INV501 Induces Strong ...

                            Details : INV501 is a novel oral small molecule candidate that can selectively enhance anti-tumor immune responses. It induces T cell activation, proliferation, and tumor-reactive cytotoxicity.

                            Brand Name : INV501

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 19, 2023

                            Lead Product(s) : INV501

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : siRNA-transfected Peripheral Blood Mononuclear Cells

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            invIOs To Present Data From Clinical Stage Cbl-b Program At SITC 2022

                            Details : APN401 (siRNA-transfected peripheral blood mononuclear cells) is an Autologous Cell Therapy using siRNA mediated silencing of Cbl-b resulting in highly activated tumor-reactive white blood cells.

                            Brand Name : APN401

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            October 18, 2022

                            Lead Product(s) : siRNA-transfected Peripheral Blood Mononuclear Cells

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : APN401

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            invIOs Goes Live with Unique Cell Therapy Platform and Clinical-Stage Immuno-Oncology Pipeline

                            Details : The first clinically validated target is the immune master-checkpoint Cbl-b; the clinical-stage lead candidate APN401 will show results in the near term on safety with data from an ongoing Phase 1b trial.

                            Brand Name : APN401

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            December 16, 2021

                            Lead Product(s) : APN401

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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