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Find Clinical Drug Pipeline Developments & Deals by Iovance Biotherapeutics

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01

Conjugates Summit
Not Confirmed
Conjugates Summit
Not Confirmed

Details : LN-145 is a ready-to-infuse TIL therapy that utilizes an autologous TIL manufacturing process, as originally developed by the NCI and further optimized by Iovance for patients with metastatic NSCLC.

Product Name : LN-145

Product Type : Cell and Gene therapy

Upfront Cash : Not Applicable

March 04, 2024

Lead Product(s) : LN-145

Therapeutic Area : Oncology

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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02

Conjugates Summit
Not Confirmed
Conjugates Summit
Not Confirmed

Details : Lovance intends to use proceeds to support the commercial launch of Amtagvi (lifileucel), a tumor-derived autologous T-cell immunotherapy for unresectable or metastatic melanoma.

Product Name : Amtagvi

Product Type : Cell and Gene therapy

Upfront Cash : Undisclosed

February 20, 2024

Lead Product(s) : Lifileucel

Therapeutic Area : Oncology

Highest Development Status : Approved

Sponsor : Jefferies LLC

Deal Size : $211.0 million

Deal Type : Public Offering

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03

Conjugates Summit
Not Confirmed
Conjugates Summit
Not Confirmed

Details : Amtagvi (lifileucel) is an engineered TIL therapy indicated for adults with unresectable or metastatic melanoma previously treated with a PD-1 blocking antibody.

Product Name : Amtagvi

Product Type : Cell and Gene therapy

Upfront Cash : Not Applicable

February 16, 2024

Lead Product(s) : Lifileucel

Therapeutic Area : Oncology

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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04

Conjugates Summit
Not Confirmed
Conjugates Summit
Not Confirmed

Details : LN-144 (lifileucel) is a tumor infiltrating lymphocyte therapy in combination with pembrolizumab is intended as a treatment for patients with advanced melanoma who progressed on or after prior anti-PD-1/L1 therapy and targeted therapy.

Product Name : LN-144

Product Type : Cell and Gene therapy

Upfront Cash : Not Applicable

September 14, 2023

Lead Product(s) : Lifileucel,Pembrolizumab

Therapeutic Area : Oncology

Highest Development Status : Phase III

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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05

Conjugates Summit
Not Confirmed
Conjugates Summit
Not Confirmed

Details : Iovance intends to use the proceeds to fund preparations for the commercial launch of LN-144 (lifileucel), when approved and to support ongoing clinical programs including its NSCLC registration-directed study and its frontline advanced melanoma Phase 3 ...

Product Name : LN-144

Product Type : Cell and Gene therapy

Upfront Cash : Undisclosed

July 13, 2023

Lead Product(s) : Lifileucel,Pembrolizumab

Therapeutic Area : Oncology

Highest Development Status : Phase III

Sponsor : Goldman Sachs & Co.

Deal Size : $172.5 million

Deal Type : Public Offering

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06

Conjugates Summit
Not Confirmed
Conjugates Summit
Not Confirmed

Details : Iovance intends to use the proceeds to fund preparations for the commercial launch of LN-144 (lifileucel), when approved and to support ongoing clinical programs including its NSCLC registration-directed study and its frontline advanced melanoma Phase 3 ...

Product Name : LN-144

Product Type : Cell and Gene therapy

Upfront Cash : Undisclosed

July 10, 2023

Lead Product(s) : Lifileucel,Pembrolizumab

Therapeutic Area : Oncology

Highest Development Status : Phase II

Sponsor : Goldman Sachs & Co.

Deal Size : $150.0 million

Deal Type : Public Offering

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07

Conjugates Summit
Not Confirmed
Conjugates Summit
Not Confirmed

Details : LN-145 TIL therapy for patients who have progressed on or after chemotherapy and anti-PD-1 therapy for advanced (unresectable or metastatic) NSCLC without EGFR, ROS or ALK genomic mutations

Product Name : LN-145

Product Type : Cell and Gene therapy

Upfront Cash : Not Applicable

July 10, 2023

Lead Product(s) : LN-145,Cyclophosphamide,Fludarabine Phosphate

Therapeutic Area : Oncology

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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08

Conjugates Summit
Not Confirmed
Conjugates Summit
Not Confirmed

Details : LN-144 (lifileucel) is a tumor infiltrating lymphocyte therapy in combination with pembrolizumab is intended as a treatment for patients with advanced melanoma who progressed on or after prior anti-PD-1/L1 therapy and targeted therapy.

Product Name : LN-144

Product Type : Cell and Gene therapy

Upfront Cash : Not Applicable

June 15, 2023

Lead Product(s) : Lifileucel,Pembrolizumab

Therapeutic Area : Oncology

Highest Development Status : Phase III

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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09

Conjugates Summit
Not Confirmed
Conjugates Summit
Not Confirmed

Details : LN-144 (lifileucel) is a tumor infiltrating lymphocyte therapy in combination with pembrolizumab is intended as a treatment for patients with advanced melanoma who progressed on or after prior anti-PD-1/L1 therapy and targeted therapy.

Product Name : LN-144

Product Type : Cell and Gene therapy

Upfront Cash : Not Applicable

May 26, 2023

Lead Product(s) : Lifileucel

Therapeutic Area : Oncology

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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10

Conjugates Summit
Not Confirmed
Conjugates Summit
Not Confirmed

Details : LN-144 (lifileucel) is a tumor infiltrating lymphocyte therapy in combination with pembrolizumab is intended as a treatment for patients with advanced melanoma who progressed on or after prior anti-PD-1/L1 therapy and targeted therapy.

Product Name : LN-144

Product Type : Cell and Gene therapy

Upfront Cash : Not Applicable

March 24, 2023

Lead Product(s) : Lifileucel

Therapeutic Area : Oncology

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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