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01

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : SNB-101 (7-ethyl-10-hydroxycamptothecin) is a first nanoparticle formulation, an active metabolite of Irinotecan, being evaluated for the treatment of small cell lung cancer.

Product Name : SNB-101

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

January 10, 2025

Lead Product(s) : Irinotecan Hydrochloride

Therapeutic Area : Oncology

Highest Development Status : Phase I/ Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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02

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : ST316 is a first-in-class peptide antagonist of the interaction between β-catenin and its co-activator, BCL9. It is being evaluated for the treatment of familial adenomatous polyposis.

Product Name : ST316

Product Type : Peptide

Upfront Cash : Inapplicable

December 19, 2024

Lead Product(s) : ST316,Irinotecan Hydrochloride

Therapeutic Area : Genetic Disease

Highest Development Status : Phase I/ Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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03

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : CX-4945 (silmitasertib) is a first-in-class small molecule drug that acts as a CK2 inhibitor. It is being evaluated for the treatment of pediatric neuroblastoma.

Product Name : CX-4945

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

December 09, 2024

Lead Product(s) : Silmitasertib,Irinotecan Hydrochloride

Therapeutic Area : Oncology

Highest Development Status : Phase I/ Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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04

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : SNB-101 (SN-38) is the first nanoparticle formulation of the anticancer drug SN-38, being evaluated for the treatment of small cell lung cancer.

Product Name : SNB-101

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

September 05, 2024

Lead Product(s) : Irinotecan Hydrochloride

Therapeutic Area : Oncology

Highest Development Status : Phase I

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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05

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : NGC-Iri is a prodrug of SN-38, the active molecule in irinotecan and Onivyde. It is currently being evaluated for the treatment of cancers.

Product Name : NGC-Iri

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

August 19, 2024

Lead Product(s) : Irinotecan Hydrochloride

Therapeutic Area : Oncology

Highest Development Status : Preclinical

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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06

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Orotecan (irinotecan HCl) is a topoisomerase-I inhibitor approved by the FDA. It is now being evaluated for the treatment of recurrent pediatric solid tumors.

Product Name : Orotecan

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

August 04, 2024

Lead Product(s) : Irinotecan Hydrochloride,Temozolomide

Therapeutic Area : Oncology

Highest Development Status : Phase I/ Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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07

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Natrunix is an immunoglobulin cloned from healthy human donor which blocks IL-1α it is being investigated in combination with chemotherapy regimen for pancreatic cancer.

Product Name : Natrunix

Product Type : Antibody

Upfront Cash : Inapplicable

June 18, 2024

Lead Product(s) : Vilamakitug,Irinotecan Hydrochloride

Therapeutic Area : Oncology

Highest Development Status : Phase I/ Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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08

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : SNB-101 (SN-38) is a first nanoparticle formulation of the anticancer drug SN-38. SN-38 is an active metabolite of Irinotecan, being evaluated for the treatment of small cell lung cancer.

Product Name : SNB-101

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

May 31, 2024

Lead Product(s) : Irinotecan Hydrochloride

Therapeutic Area : Oncology

Highest Development Status : Phase I

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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09

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : Ipsen acquired exclusive commercialization rights for Onivyde, an encapsulated formulation of irinotecan as a first-line treatment for metastatic adenocarcinoma of the pancreas in the US.

Product Name : Onivyde

Product Type : Other Small Molecule

Upfront Cash : $575.0 million

March 27, 2024

Lead Product(s) : Irinotecan Hydrochloride,Fluorouracil

Therapeutic Area : Oncology

Highest Development Status : Approved FDF

Sponsor : Ipsen

Deal Size : $1,025.0 million

Deal Type : Acquisition

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10

BePharma
Not Confirmed
BePharma
Not Confirmed

Details : SNB-101 (SN-38) is the world's first nanoparticle formulation of the anticancer drug SN-38, evaluated for treating pancreatic cancer using dual nano-micelle technology for delivery.

Product Name : SNB-101

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

February 29, 2024

Lead Product(s) : Irinotecan Hydrochloride

Therapeutic Area : Oncology

Highest Development Status : Phase I

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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