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    [{"orgOrder":0,"company":"Incannex Healthcare","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"AUSTRALIA","productType":"Controlled Substance","year":"2022","type":"Inapplicable","leadProduct":"Cannabidiol","moa":"||CB1\/2 receptor","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase I","graph3":"Incannex Healthcare","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Incannex Healthcare \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Incannex Healthcare \/ Inapplicable"},{"orgOrder":0,"company":"Incannex Healthcare","sponsor":"Curia","pharmaFlowCategory":"D","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"AUSTRALIA","productType":"Controlled Substance","year":"2022","type":"Agreement","leadProduct":"Cannabidiol","moa":"||CB1\/2 receptor","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase I","graph3":"Incannex Healthcare","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Incannex Healthcare \/ Curia","highestDevelopmentStatusID":"6","companyTruncated":"Incannex Healthcare \/ Curia"},{"orgOrder":0,"company":"Vectura Ltd","sponsor":"Incannex Healthcare","pharmaFlowCategory":"D","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"UNITED KINGDOM","productType":"Controlled Substance","year":"2021","type":"Agreement","leadProduct":"Cannabidiol","moa":"||CB1\/2 receptor","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Preclinical","graph3":"Vectura Ltd","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Oral Powder for Inhalation","sponsorNew":"Vectura Ltd \/ Incannex Healthcare","highestDevelopmentStatusID":"4","companyTruncated":"Vectura Ltd \/ Incannex Healthcare"},{"orgOrder":0,"company":"Sedana Medical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"SWEDEN","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Isoflurane","moa":"Glycine positive receptor","graph1":"Neurology","graph2":"Approved FDF","graph3":"Sedana Medical","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Sedana Medical \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Sedana Medical \/ Inapplicable"},{"orgOrder":0,"company":"Sedana Medical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"SWEDEN","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Isoflurane","moa":"Glycine positive receptor","graph1":"Neurology","graph2":"Approved FDF","graph3":"Sedana Medical","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Sedana Medical \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Sedana Medical \/ Inapplicable"},{"orgOrder":0,"company":"Sedana Medical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"SWEDEN","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Isoflurane","moa":"Glycine positive receptor","graph1":"Neurology","graph2":"Approved FDF","graph3":"Sedana Medical","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Sedana Medical \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Sedana Medical \/ Inapplicable"},{"orgOrder":0,"company":"Sedana Medical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"SWEDEN","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Isoflurane","moa":"Glycine positive receptor","graph1":"Neurology","graph2":"Approved FDF","graph3":"Sedana Medical","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Sedana Medical \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Sedana Medical \/ Inapplicable"},{"orgOrder":0,"company":"Sedana Medical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"SWEDEN","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Isoflurane","moa":"Glycine positive receptor","graph1":"Neurology","graph2":"Approved FDF","graph3":"Sedana Medical","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Sedana Medical \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Sedana Medical \/ Inapplicable"},{"orgOrder":0,"company":"Sedana Medical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"SWEDEN","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Isoflurane","moa":"Glycine positive receptor","graph1":"Neurology","graph2":"Approved FDF","graph3":"Sedana Medical","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Sedana Medical \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Sedana Medical \/ Inapplicable"}]

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                            01

                            Vectura Ltd

                            United Kingdom
                            German Wound Congress
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                            Lead Product(s) : Cannabidiol,Isoflurane

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Preclinical

                            Sponsor : Incannex Healthcare

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Vectura Signs Pre-Clinical Development Agreement with Incannex to Advance IHL-216A for the Treatment of Trauma...

                            Details : Under the terms of the agreement, Vectura will undertake formulation screening studies, manufacturing process optimisation studies and stability assessments, as well as manufacturing a laboratory-scale batch of IHL-216A (Cannabidiol) to support toxicolog...

                            Product Name : IHL-216A

                            Product Type : Controlled Substance

                            Upfront Cash : Undisclosed

                            June 22, 2021

                            Lead Product(s) : Cannabidiol,Isoflurane

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Preclinical

                            Sponsor : Incannex Healthcare

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            02

                            Sedana Medical

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                            Sedana Medical

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                            Lead Product(s) : Isoflurane

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sedana Medical Completes Patient Recruitment for INSPiRE-ICU 1 Clinical Trial in the US

                            Details : Sedaconda (isoflurane) is an inhalation anesthetic that acts as a GABAA receptor modulator, decreasing motor function and inhibiting excitatory neurotransmission via NMDA receptors.

                            Product Name : Sedaconda

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 25, 2024

                            Lead Product(s) : Isoflurane

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Sedana Medical

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                            Sedana Medical

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                            Lead Product(s) : Isoflurane

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sedana Medical Receives FDA Fast Track Designation in The United States

                            Details : Sedaconda (isoflurane), a general inhalation anesthetic, acts as a positive allosteric GABAA receptor modulator. It enhances glycine receptor activity, which decreases motor function and inhibits NMDA glutamate receptor, which mediates excitatory neurotr...

                            Product Name : Sedaconda

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 01, 2023

                            Lead Product(s) : Isoflurane

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Incannex Healthcare

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                            German Wound Congress
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                            Incannex Healthcare

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                            Lead Product(s) : Cannabidiol,Isoflurane

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Incannex Completes Positive Pre-IND Meeting with US FDA on IHL-216A for Treatment of Concussion and Traumatic ...

                            Details : IHL-216A (cannabidiol) is a CB1 receptor negative allosteric modulator. It is being evaluated in preclinical studies in combination with Isoflurane for the treatment of traumatic brain injury & concussion.

                            Product Name : IHL-675A

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            November 10, 2022

                            Lead Product(s) : Cannabidiol,Isoflurane

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Incannex Healthcare

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                            German Wound Congress
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                            Incannex Healthcare

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                            Lead Product(s) : Cannabidiol,Isoflurane

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Preclinical

                            Sponsor : Curia

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Incannex Engages Curia to Scale-up Manufacture of cGMP IHL-216A

                            Details : IHL-216A (cannabidiol) has been observed to have a greater neuroprotective effect in a rodent model of sports concussion than CBD, and results indicate restoration of the spatial memory deficit post-concussion with IHL-216A administration.

                            Product Name : IHL-675A

                            Product Type : Controlled Substance

                            Upfront Cash : Undisclosed

                            February 08, 2022

                            Lead Product(s) : Cannabidiol,Isoflurane

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Preclinical

                            Sponsor : Curia

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            06

                            Sedana Medical

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                            Sedana Medical

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                            Lead Product(s) : Isoflurane

                            Therapeutic Area : Neurology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sedana Medical receives IND approval for US trials

                            Details : Company received IND clearance from the USFDA to initiate phase III pivotal clinical trials with its combination registration of medical device Sedaconda ACD and pharmaceutical Sedaconda (isoflurane) for sedation of mechanically ventilated intensive care...

                            Product Name : Sedaconda

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 23, 2021

                            Lead Product(s) : Isoflurane

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Sedana Medical

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                            German Wound Congress
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                            Sedana Medical

                            Sweden arrow
                            German Wound Congress
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                            Lead Product(s) : Isoflurane

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sedana Medical Submits IND for US Clinical Trials

                            Details : Sedaconda (isoflurane) for inhaled sedation used in combination with medical device Sedaconda ACD, it's primary endpoint in each study will is effective and non-inferior to propofol for sedation of mechanically ventilated patients in the intensive care u...

                            Product Name : Sedaconda

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 24, 2021

                            Lead Product(s) : Isoflurane

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Sedana Medical

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                            German Wound Congress
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                            Sedana Medical

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                            German Wound Congress
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                            Lead Product(s) : Isoflurane

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sedana Medical Receives Approval for European Dossier

                            Details : The topline results, announced in July 2020, showed that the study reached its primary goal; to show that Sedaconda administered via AnaConDa is an effective sedation method for ventilated ICU patients, comparable to propofol.

                            Product Name : Sedaconda

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 20, 2021

                            Lead Product(s) : Isoflurane

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Sedana Medical

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                            German Wound Congress
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                            Sedana Medical

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                            German Wound Congress
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                            Lead Product(s) : Isoflurane

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sedana Medical Announces Positive Top Line Result in Pivotal IsoConDa Study

                            Details : The results indicate that IsoConDa is an effective and safe sedation method and will form the basis for the company's application for European market approval later this autumn.

                            Product Name : Sedaconda

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 07, 2020

                            Lead Product(s) : Isoflurane

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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