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    [{"orgOrder":0,"company":"Akers Biosciences","sponsor":"MyMD Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"","productType":"Small molecule","year":"2020","type":"Merger","leadProduct":"Isomyosamine","moa":"","graph1":"Immunology","graph2":"Phase I","graph3":"Akers Biosciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"","sponsorNew":"Akers Biosciences \/ MyMD Pharmaceuticals","highestDevelopmentStatusID":"6","companyTruncated":"Akers Biosciences \/ MyMD Pharmaceuticals"},{"orgOrder":0,"company":"MyMD Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Isomyosamine","moa":"TNF alpha","graph1":"Immunology","graph2":"Phase I","graph3":"MyMD Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph 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Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Isomyosamine","moa":"","graph1":"Immunology","graph2":"IND Enabling","graph3":"MyMD Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"MyMD Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"MyMD Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"MyMD Pharmaceuticals","sponsor":"PharmaCyte Biotech","pharmaFlowCategory":"D","therapeuticArea":"Musculoskeletal","country":"","productType":"Small molecule","year":"2024","type":"Financing","leadProduct":"Isomyosamine","moa":"","graph1":"Musculoskeletal","graph2":"Phase II","graph3":"MyMD Pharmaceuticals","amount2":0.01,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Musculoskeletal","amount2New":0.01,"dosageForm":"","sponsorNew":"MyMD Pharmaceuticals \/ PharmaCyte Biotech","highestDevelopmentStatusID":"8","companyTruncated":"MyMD Pharmaceuticals \/ PharmaCyte Biotech"},{"orgOrder":0,"company":"TNF Pharmaceuticals","sponsor":"Prevail Partners","pharmaFlowCategory":"D","therapeuticArea":"Musculoskeletal","country":"","productType":"Small molecule","year":"2024","type":"Financing","leadProduct":"Isomyosamine","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"TNF Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"TNF Pharmaceuticals \/ Prevail Partners","highestDevelopmentStatusID":"14","companyTruncated":"TNF Pharmaceuticals \/ Prevail Partners"},{"orgOrder":0,"company":"TNF Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Musculoskeletal","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Isomyosamine","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"TNF Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"TNF Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"TNF Pharmaceuticals \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals for Isomyosamine, (+/-)-

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                            01

                            TNF Pharmaceuticals

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                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Prevail Partners

                            Deal Size : Undisclosed

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            TNF Pharmaceuticals Announces Strategic Equity Investment Priced at a Premium to Market

                            Details : The proceeds will provide clinical services for the next Phase 2 clinical study using company's proprietary drug, MYMD-1, a novel, orally dosed TNFα inhibitor, in sarcopenia/frailty.

                            Brand Name : MYMD-1

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 02, 2024

                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Prevail Partners

                            Deal Size : Undisclosed

                            Deal Type : Financing

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                            02

                            TNF Pharmaceuticals

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                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            TNF Pharmaceuticals Advances Lead Program For Age-Related Decline

                            Details : MYMD-1 is a small molecule shown to block excessive activity of TNF-alpha (TNF-α) in the blood to regulate the immuno-metabolic system. It is being evaluated for treatment of Sarcopenia.

                            Brand Name : MYMD-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 21, 2024

                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            MyMD Pharmaceuticals

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                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : PharmaCyte Biotech

                            Deal Size : $7.0 million

                            Deal Type : Financing

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                            PharmaCyte Biotech Makes $7 Million Investment in MyMD for Inflammatory Disease

                            Details : The financing aims to support MyMD in advancing its lead product MYMD-1 (isomyosamine), which is being evaluated in the mid-stage clinical trial studies for the treatment of sarcopenia.

                            Brand Name : MYMD-1

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            May 21, 2024

                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : PharmaCyte Biotech

                            Deal Size : $7.0 million

                            Deal Type : Financing

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                            04

                            MyMD Pharmaceuticals

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                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Immunology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            MyMD Pharmaceuticals Plans FDA-Cleared Phase 2 Clinical Trial of MYMD-1 in Rheumatoid Arthritis

                            Details : MYMD-1 (isomyosamine), a next generation, oral selective inhibitor of tumor necrosis factor-alpha, a driver of chronic inflammation, being studied for rheumatoid arthritis.

                            Brand Name : MYMD-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 06, 2023

                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Immunology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            MyMD Pharmaceuticals

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                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            MyMD Pharmaceuticals Reports Statistically Significant Positive Topline Phase 2 Results for Next Generation Or...

                            Details : MYMD-1, a next generation, oral selective inhibitor of tumor necrosis factor-alpha (TNF-α), a driver of chronic inflammation, is being studied to slow the aging process, prevent sarcopenia and frailty, and extend healthy lifespan.

                            Brand Name : MYMD-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 31, 2023

                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            MyMD Pharmaceuticals

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                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            MyMD Pharmaceuticals® Provides Dosing Update on Phase 2 Multi-Center Clinical Trial of MYMD-1® as a Therapy ...

                            Details : MYMD-1 is an oral next-generation TNF-α inhibitor with the potential to transform the way that TNF-α based diseases are treated due to its selectivity and ability to cross the blood brain barrier. It is being investigated as therapy for delaying aging.

                            Brand Name : MYMD-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 12, 2023

                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            MyMD Pharmaceuticals

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                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            MyMD Pharmaceuticals® and Charles River Present Positive Data for Next Generation, Oral TNF-α Inhibitor MYMD...

                            Details : MYMD-1 is an oral next-generation TNF-α inhibitor with the potential to transform the way that TNF-α based diseases are treated due to its selectivity and ability to cross the blood brain barrier. It is being investigated for rheumatoid arthritis.

                            Brand Name : MYMD-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 20, 2023

                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            MyMD Pharmaceuticals

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                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            MyMD Pharmaceuticals® Announces Upcoming Presentation of Preclinical Rheumatoid Arthritis Data for Oral TNF-Î...

                            Details : MYMD-1 is an oral next-generation TNF-α inhibitor with the potential to transform the way that TNF-α based diseases are treated due to its selectivity and ability to cross the blood brain barrier.

                            Brand Name : MYMD-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 28, 2023

                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            MyMD Pharmaceuticals

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                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase I

                            Sponsor : Katalyst Securities

                            Deal Size : $15.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            MyMD Announces $15 Million Offering with Existing Investors

                            Details : The financing will support the continued development of MYMD-1 for sarcopenia, an aging indication. MYMD-1® regulates the immuno-metabolic system through the modulation of numerous pro-inflammatory cytokines, including TNF-α, IL-6 and IL-17A.

                            Brand Name : MYMD-1

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            February 21, 2023

                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase I

                            Sponsor : Katalyst Securities

                            Deal Size : $15.0 million

                            Deal Type : Public Offering

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                            10

                            MyMD Pharmaceuticals

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                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            MyMD Pharmaceuticals® Announces Upcoming Presentation of Late-Breaking Data for MYMD-1® at the 2022 British ...

                            Details : MYMD-1 is an oral next-generation TNF-α inhibitor with the potential to transform the way that TNF-α based diseases are treated due to its selectivity and ability to cross the blood brain barrier.

                            Brand Name : MYMD-1

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 17, 2022

                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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