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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Cancer Research
                          Not Confirmed
                          Cancer Research
                          Not Confirmed

                          Details : Tremfya (guselkumab) is the first approved fully-human, monoclonal antibody that blocks IL-23. It is being evaluated for the treatment of adults with moderately to severely active ulcerative colitis.

                          Product Name : Tremfya

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          March 20, 2025

                          Lead Product(s) : Guselkumab

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Cancer Research
                          Not Confirmed
                          Cancer Research
                          Not Confirmed

                          Details : JNJ-2113 (icotrokinra) is a first-in-class oral peptide that selectively blocks IL-23 receptor. It is being studied in adults & adolescents 12 years of age & older with moderate-to-severe plaque PsO.

                          Product Name : JNJ-2113

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          March 08, 2025

                          Lead Product(s) : Icotrokinra

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Cancer Research
                          Not Confirmed
                          Cancer Research
                          Not Confirmed

                          Details : Tremfya (guselkumab) is the first approved fully-human, monoclonal antibody that blocks IL-23. It is being evaluated for the treatment of adults with moderately to severely active ulcerative colitis.

                          Product Name : Tremfya

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          February 28, 2025

                          Lead Product(s) : Guselkumab

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Cancer Research
                          Not Confirmed
                          Cancer Research
                          Not Confirmed

                          Details : Darzalex (daratumumab) a CD38 inhibitor, being evaluated in combination with bortezomib, lenalidomide, dexamethasone for the treatment of newly diagnosed multiple myeloma.

                          Product Name : Darzalex

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          February 28, 2025

                          Lead Product(s) : Daratumumab,Lenalidomide,Bortezomib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Cancer Research
                          Not Confirmed
                          Cancer Research
                          Not Confirmed

                          Details : ExPEC9V (9-valent extraintestinal pathogenic escherichia coli vaccine) is being evaluated for invasive extraintestinal pathogenic escherichia coli disease in adults aged 60 years And older.

                          Product Name : VAC52416

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          February 17, 2025

                          Lead Product(s) : ExPEC9V

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Recipient : Sanofi

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Cancer Research
                          Not Confirmed
                          Cancer Research
                          Not Confirmed

                          Details : Rybrevant (amivantamab) is a fully-human EGFR-MET bispecific antibody. It is indicated in combination with Lazertinib for the treatment of Advanced or Metastatic Non-small Cell Lung Cancer.

                          Product Name : Undisclosed

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 30, 2024

                          Lead Product(s) : Amivantamab,Lazertinib,Dexamethasone

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Cancer Research
                          Not Confirmed
                          Cancer Research
                          Not Confirmed

                          Details : Carvykti (ciltacabtagene autoleucel) is an FDA-approved genetically modified autologous T cell immunotherapy that inhibits BCMA. It is administered intravenously for the treatment of r/r MM in adults.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 10, 2024

                          Lead Product(s) : Ciltacabtagene Autoleucel

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Cancer Research
                          Not Confirmed
                          Cancer Research
                          Not Confirmed

                          Details : Carvykti (ciltacabtagene autoleucel) is an FDA-approved genetically modified autologous T cell immunotherapy that inhibits BCMA. It is administered intravenously for the treatment of r/r MM in adults.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 09, 2024

                          Lead Product(s) : Ciltacabtagene Autoleucel

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Recipient : Legend Biotech

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Cancer Research
                          Not Confirmed
                          Cancer Research
                          Not Confirmed

                          Details : JNJ-2113 (icotrokinra) is a first and only targeted oral peptide that is designed to selectively block the IL-23R. It is under clinical development for the treatment of moderate-to-severe psoriasis.

                          Product Name : JNJ-2113

                          Product Type : Peptide

                          Upfront Cash : Not Applicable

                          November 18, 2024

                          Lead Product(s) : Icotrokinra

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Protagonist Therapeutics

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Cancer Research
                          Not Confirmed
                          Cancer Research
                          Not Confirmed

                          Details : Rybrevant (amivantamab) is a fully-human EGFR-MET bispecific antibody. It is indicated in combination with Lazertinib for the treatment of Advanced or Metastatic Non-small Cell Lung Cancer.

                          Product Name : Rybrevant

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 15, 2024

                          Lead Product(s) : Amivantamab,Lazertinib,Dexamethasone

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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