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    [{"orgOrder":0,"company":"Janux Therapeutics","sponsor":"Merck & Co","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2020","type":"Collaboration","leadProduct":"Tumor Activated T Cell Engager","moa":"","graph1":"Oncology","graph2":"Discovery","graph3":"Janux Therapeutics","amount2":1,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":1,"dosageForm":"","sponsorNew":"Janux Therapeutics \/ Merck","highestDevelopmentStatusID":"2","companyTruncated":"Janux Therapeutics \/ Merck"},{"orgOrder":0,"company":"Janux Therapeutics","sponsor":"Avalon GloboCare","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2021","type":"Series A Financing","leadProduct":"TROP2-TRACTr based therapeutics","moa":"Trop2","graph1":"Oncology","graph2":"Preclinical","graph3":"Janux Therapeutics","amount2":0.059999999999999998,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.059999999999999998,"dosageForm":"","sponsorNew":"Janux Therapeutics \/ Avalon Ventures","highestDevelopmentStatusID":"4","companyTruncated":"Janux Therapeutics \/ Avalon Ventures"},{"orgOrder":0,"company":"Janux Therapeutics","sponsor":"BVF Partners L.P","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2021","type":"Series B Financing","leadProduct":"Undisclosed","moa":"PSMA\/CD3","graph1":"Oncology","graph2":"Preclinical","graph3":"Janux Therapeutics","amount2":0.13,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.13,"dosageForm":"","sponsorNew":"Janux Therapeutics \/ BVF Partners L.P","highestDevelopmentStatusID":"4","companyTruncated":"Janux Therapeutics \/ BVF Partners L.P"},{"orgOrder":0,"company":"Janux Therapeutics","sponsor":"Avalon 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Applicable","leadProduct":"JANX007","moa":"PSMA\/CD3","graph1":"Oncology","graph2":"Phase I","graph3":"Janux Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Janux Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Janux Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Janux Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"JANX008","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Janux Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Janux Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Janux Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Janux Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"JANX008","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Janux Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Janux Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Janux Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Janux Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"JANX007","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Janux Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Janux Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Janux Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Janux Therapeutics","sponsor":"BofA Securities","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Public Offering","leadProduct":"JANX007","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Janux Therapeutics","amount2":0.17999999999999999,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.29999999999999999,"dosageForm":"Infusion","sponsorNew":"Janux Therapeutics \/ BofA Securities","highestDevelopmentStatusID":"6","companyTruncated":"Janux Therapeutics \/ BofA Securities"},{"orgOrder":0,"company":"Janux Therapeutics","sponsor":"BofA Securities","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Public Offering","leadProduct":"JANX007","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Janux Therapeutics","amount2":0.29999999999999999,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.29999999999999999,"dosageForm":"Infusion","sponsorNew":"Janux Therapeutics \/ BofA Securities","highestDevelopmentStatusID":"6","companyTruncated":"Janux Therapeutics \/ BofA Securities"}]

    Find Clinical Drug Pipeline Developments & Deals by Janux Therapeutics

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                            01

                            Janux Therapeutics

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                            CPhI India 2024
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                            Janux Therapeutics

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                            Lead Product(s) : JANX007

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : BofA Securities

                            Deal Size : $296.5 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Janux Therapeutics Announces Pricing Of $296.5 Million Underwritten Public Offering

                            Details : Proceeds will advance JANX007 for metastatic castration-resistant prostate cancer in Phase 1 trials.

                            Brand Name : JANX007

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            February 29, 2024

                            Lead Product(s) : JANX007

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : BofA Securities

                            Deal Size : $296.5 million

                            Deal Type : Public Offering

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                            02

                            Janux Therapeutics

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                            CPhI India 2024
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                            Janux Therapeutics

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                            Lead Product(s) : JANX007

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : BofA Securities

                            Deal Size : $175.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Janux Therapeutics Announces Proposed Public Offering of Common Stock

                            Details : Proceeds will support the clinical advancement of JANX007, designed to target PSMA and currently being evaluated in clinical trials for metastatic castration-resistant prostate cancer.

                            Brand Name : JANX007

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            February 27, 2024

                            Lead Product(s) : JANX007

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : BofA Securities

                            Deal Size : $175.0 million

                            Deal Type : Public Offering

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                            03

                            Janux Therapeutics

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                            CPhI India 2024
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                            Janux Therapeutics

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                            Lead Product(s) : JANX007

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Janux Therapeutics Announces Positive Interim Clinical Data from Phase 1a Dose Escalation for PSMA-TRACTr JANX...

                            Details : JANX007 is a novel Tumor Activated T Cell Engager (TRACTr) that targets PSMA and is being investigated in a Phase 1 clinical trial in adult subjects with metastatic castration-resistant prostate cancer (mCRPC).

                            Brand Name : JANX007

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            July 17, 2023

                            Lead Product(s) : JANX007

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Janux Therapeutics

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                            CPhI India 2024
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                            Janux Therapeutics

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                            Lead Product(s) : JANX008

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Janux Therapeutics Announces First Patient Dosed with JANX008 in First-in-Human Phase 1 Clinical Trial in Pati...

                            Details : JANX008 is a TRACTr that targets EGFR and is being studied in a Phase 1 trial for the treatment of multiple solid cancers including colorectal cancer, squamous cell carcinoma of the head and neck, non-small cell lung cancer, and renal cell carcinoma.

                            Brand Name : JANX008

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 20, 2023

                            Lead Product(s) : JANX008

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Janux Therapeutics

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                            Janux Therapeutics

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                            Lead Product(s) : JANX008

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Janux Therapeutics Announces Submission of Investigational New Drug Application for JANX008, an EGFR-TRACTr fo...

                            Details : JANX008 is a double-masked TRACTr in which the EGFR-binding domain and the T cell-specific binding domain (CD3) is masked. It might prove to be an attractive solid tumor therapeutic.

                            Brand Name : JANX008

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            December 27, 2022

                            Lead Product(s) : JANX008

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Janux Therapeutics

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                            Janux Therapeutics

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                            Lead Product(s) : JANX007

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Janux Therapeutics Announces First Patient Dosed with JANX007 in First-in-Human Phase 1 Clinical Trial in Pati...

                            Details : JANX007 is a prostate-specific membrane antigen (PSMA) directed T cell engager (TCE) and is the first product candidate utilizing Janux’s TRACTr platform to be administered in humans. JANX007 has the potential for tumor-selective T cell activation and ...

                            Brand Name : JANX007

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 12, 2022

                            Lead Product(s) : JANX007

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Janux Therapeutics

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                            Janux Therapeutics

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                            Lead Product(s) : JANX007

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Janux Therapeutics Announces FDA Clearance of Investigational New Drug Application for JANX007, a PSMA-TRACTr ...

                            Details : JANX007 is the Company’s lead novel T cell engager (TCE) therapeutic from its TRACTr platform. Janux plans to initiate a Phase 1 clinical trial for JANX007 in the second half of 2022.

                            Brand Name : JANX007

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            May 31, 2022

                            Lead Product(s) : JANX007

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Janux Therapeutics

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                            Janux Therapeutics

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                            Lead Product(s) : JANX007

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Janux Therapeutics to Present Preclinical Data at the 18th Annual PEGS Boston for PSMA-TRACTr and EGFR-TRACTr

                            Details : PSMA-TRACTr (JANX007) and EGFR-TRACTr (JANX008), a novel Tumor Activated T Cell Engager therapeutic exhibit enhanced safety and PK properties relative to unmasked T cell engagers.

                            Brand Name : JANX007

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 26, 2022

                            Lead Product(s) : JANX007

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Janux Therapeutics

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                            Janux Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Avalon Ventures

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Cancer Biotech Janux Therapeutics Files for $100 Million IPO

                            Details : The company’s TRACTr technology is engineered to overcome limitations of current immuno-oncology T-cell therapies, primarily dose-limiting toxicities, poor pharmacokinetic profiles, and limited efficacy.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            May 21, 2021

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Avalon Ventures

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

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                            10

                            Janux Therapeutics

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                            Janux Therapeutics

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : BVF Partners L.P

                            Deal Size : $125.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Janux Therapeutics Closes $125 Million Series B Financing to Advance Next Generation T Cell Engager Immunother...

                            Details : The proceeds of the financing will help support the advancement of Janux’s pipeline of next generation T cell engager immunotherapies, including a PSMA-TRACTr, EGFR-TRACTr, and TROP2-TRACTr, into initial proof of concept clinical trials.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            April 20, 2021

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : BVF Partners L.P

                            Deal Size : $125.0 million

                            Deal Type : Series B Financing

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