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                          01

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : JBI-802 is a first-in-class, orally administered CoREST Inhibitor, small molecule drug candidate, which is currently being evaluated for the treatment of solid tumors.

                          Product Name : JBI-802

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 25, 2024

                          Lead Product(s) : JBI-802

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : JBI-802 is a first-in-class CoREST inhibitor with dual action on LSD1 and HDAC6, undergoing phase 1/2 trials for essential thrombocythemia and related neoplasms.

                          Product Name : JBI-802

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 01, 2024

                          Lead Product(s) : JBI-802

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : JBI-802 is an oral, potent and selective dual inhibitor of two epigenetic targets of the CoREST complex: LSD1 and HDAC6. It targets stem cell modulation by inhibiting LSD1 and modulates immune suppression with isoform selective HDAC6 inhibition.

                          Product Name : JBI-802

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 01, 2023

                          Lead Product(s) : JBI-802

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : JBI-802, a novel dual LSD1 and HDAC6 Inhibitor received FDA Clearance of IND, on the basis of preclinical data that has demonstrated synergistic anti-tumor activity, and a favorable safety profile with no significant safety concerns or accumulation.

                          Product Name : JBI-802

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          May 01, 2022

                          Lead Product(s) : JBI-802

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : JBI-802 is a first-in-class, small-molecule, orally administered selective dual inhibitor of two epigenetic targets of the CoREST complex: LSD1 and HDAC6, that has demonstrated synergistic anti-tumor activity in animal models.

                          Product Name : JBI-802

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 26, 2022

                          Lead Product(s) : JBI-802

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : As part of the collaboration, Jubilant Therapeutics sought to determine the mechanism for its potentially first-in-class dual epigenetic inhibitor targeting melanoma, myelodysplastic syndrome (MDS), and acute myeloid leukemia (AML) and select solid tumor...

                          Product Name : JBI-802

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 11, 2020

                          Lead Product(s) : JBI-802

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Jubilant Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          07

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : Preclinical data demonstrated that JBI-802 has strong efficacy in multiple in vivo cancer models mediated by LSD1 and HDAC6 inhibition, it has excellent selectivity against other HDACs and superior in vivo efficacy compared to single agents targeting LSD...

                          Product Name : JBI-802

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 22, 2020

                          Lead Product(s) : JBI-802

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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