Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : JBI-802
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Jubilant Starts Trials for JBI-802 And JBI-778 in Global Studies
Details : JBI-802 is a first-in-class, orally administered CoREST Inhibitor, small molecule drug candidate, which is currently being evaluated for the treatment of solid tumors.
Product Name : JBI-802
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 25, 2024
Lead Product(s) : JBI-802
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : JBI-802
Therapeutic Area : Hematology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
JBI-802 Phase I Data Suggests Potential in Immunotherapy-Resistant Tumors
Details : JBI-802 is a first-in-class CoREST inhibitor with dual action on LSD1 and HDAC6, undergoing phase 1/2 trials for essential thrombocythemia and related neoplasms.
Product Name : JBI-802
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 01, 2024
Lead Product(s) : JBI-802
Therapeutic Area : Hematology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : JBI-802
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : JBI-802 is an oral, potent and selective dual inhibitor of two epigenetic targets of the CoREST complex: LSD1 and HDAC6. It targets stem cell modulation by inhibiting LSD1 and modulates immune suppression with isoform selective HDAC6 inhibition.
Product Name : JBI-802
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 01, 2023
Lead Product(s) : JBI-802
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : JBI-802
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : JBI-802, a novel dual LSD1 and HDAC6 Inhibitor received FDA Clearance of IND, on the basis of preclinical data that has demonstrated synergistic anti-tumor activity, and a favorable safety profile with no significant safety concerns or accumulation.
Product Name : JBI-802
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 01, 2022
Lead Product(s) : JBI-802
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : JBI-802
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : JBI-802 is a first-in-class, small-molecule, orally administered selective dual inhibitor of two epigenetic targets of the CoREST complex: LSD1 and HDAC6, that has demonstrated synergistic anti-tumor activity in animal models.
Product Name : JBI-802
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 26, 2022
Lead Product(s) : JBI-802
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : JBI-802
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Jubilant Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Jubilant Therapeutics and OneThree Biotech Collaborate to Advance Precision Oncology
Details : As part of the collaboration, Jubilant Therapeutics sought to determine the mechanism for its potentially first-in-class dual epigenetic inhibitor targeting melanoma, myelodysplastic syndrome (MDS), and acute myeloid leukemia (AML) and select solid tumor...
Product Name : JBI-802
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
December 11, 2020
Lead Product(s) : JBI-802
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Jubilant Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : JBI-802
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Jubilant Therapeutics Presents Preclinical Data at the American Association for Cancer Research
Details : Preclinical data demonstrated that JBI-802 has strong efficacy in multiple in vivo cancer models mediated by LSD1 and HDAC6 inhibition, it has excellent selectivity against other HDACs and superior in vivo efficacy compared to single agents targeting LSD...
Product Name : JBI-802
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 22, 2020
Lead Product(s) : JBI-802
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable