Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : HRS-5346
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Merck & Co
Deal Size : $1,970.0 million
Deal Type : Licensing Agreement
Merck Licenses HRS-5346, Oral Lipoprotein(a) Inhibitor, from Jiangsu Hengrui
Details : Under the licensing agreement, Merck will hold the rights of HRS-5346, an investigational oral small molecule Lp(a), inhibitor currently being evaluated in a Phase 2 clinical trial in China.
Product Name : HRS-5346
Product Type : Other Small Molecule
Upfront Cash : $200.0 million
March 25, 2025
Lead Product(s) : HRS-5346
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Merck & Co
Deal Size : $1,970.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Camrelizumab,Rivoceranib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Elevar Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Rejects Hengrui, Elevar's PD-1 Cancer Drug Combo—Again
Details : SHR-1210 (camrelizumab) in combination with rivoceranib (apatinib) is being evluated for the treatment of first-line therapy in patients With advanced hepatocellular carcinoma.
Product Name : SHR-1210
Product Type : Antibody
Upfront Cash : Inapplicable
March 21, 2025
Lead Product(s) : Camrelizumab,Rivoceranib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Elevar Therapeutics
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SHR-4849
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Ideaya Biosciences
Deal Size : $1,045.0 million
Deal Type : Licensing Agreement
IDEAYA, Hengrui License Phase 1 DLL3 ADC SHR-4849 Targeting SCLC And NET Tumors
Details : Under the licensing agreement, IDEAYA will develop and commercialize SHR-4849 for solid tumors, including SCLC and NET, globally, excluding Greater China.
Product Name : SHR-4849
Product Type : Large molecule
Upfront Cash : $75.0 million
December 29, 2024
Lead Product(s) : SHR-4849
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Ideaya Biosciences
Deal Size : $1,045.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Study Phase : Discovery
Recipient : Medicilon
Deal Size : Undisclosed
Deal Type : Collaboration
Medicilon & Hengrui Pharma Deepen Collaboration on ADCs, Small Nucleic Acids, & CGT Drugs
Details : Medicilon & Hengrui will collaborate to focus on the preclinical evaluation of new drug modalities such as ADCs, small molecules, etc & to advance the innovation to compete on an international level.
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Undisclosed
July 31, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Technology
Highest Development Status : Discovery
Recipient : Medicilon
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Rivoceranib,Camrelizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : Elevar Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Elevar Therapeutics Plans NDA Resubmission for Hepatocellular Carcinoma Treatment
Details : Aitan (rivoceranib), a VEGFR-2 inhibitor, is being investigated with SHR-1210 (camrelizumab) and is already approved in China. The company has resubmitted its NDA to the FDA for unresectable HCC.
Product Name : Aitan
Product Type : Small molecule
Upfront Cash : Not Applicable
July 09, 2024
Lead Product(s) : Rivoceranib,Camrelizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : Elevar Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Surufatinib,Camrelizumab
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Recipient : Hutchmed
Deal Size : Undisclosed
Deal Type : Collaboration
HUTCHMED Initiates Phase II/III Trial of Surufatinib & Camrelizumab for Pancreatic Cancer
Details : Hutchmed will initiate a clinical advancement of their lead product Sulanda (surufatinib) in combination with camrelizumab for the treatment of naïve pancreatic ductal adenocarcinoma.
Product Name : Sulanda
Product Type : Small molecule
Upfront Cash : Undisclosed
May 15, 2024
Lead Product(s) : Surufatinib,Camrelizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Recipient : Hutchmed
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Approved
Recipient : Mycovia Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : VIVJOA® (oteseconazole) is an azole antifungal and designed to selectively inhibit fungal CYP51, which is indicated for the treatment of severe vulvovaginal candidiasis (VVC).
Product Name : Vivjoa
Product Type : Small molecule
Upfront Cash : Not Applicable
August 21, 2023
Lead Product(s) : Oteseconazole
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Recipient : Mycovia Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Rivoceranib,Camrelizumab
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : Elevar Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Apatinib (rivoceranib) is a tyrosine kinase inhibitor that selectively inhibits the VEGFR-2 in combination with AiRuiKa (camrelizumab) a humanized mAb targeting the PD-1 receptor, is being investigated for unresectable hepatocellular carcinoma.
Product Name : Apatinib
Product Type : Small molecule
Upfront Cash : Not Applicable
May 17, 2023
Lead Product(s) : Rivoceranib,Camrelizumab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : Elevar Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Camrelizumab,Rivoceranib
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Camrelizumab (SHR-1210) is a humanized monoclonal antibody targeting the programmed death-1 (PD-1) receptor. Blockade of the PD-1/PD-L1 signaling pathway is a therapeutic strategy showing success in a wide variety of solid and hematological cancers.
Product Name : SHR-1210
Product Type : Large molecule
Upfront Cash : Not Applicable
September 10, 2022
Lead Product(s) : Camrelizumab,Rivoceranib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Camrelizumab,Rivoceranib
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : Elevar Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Camrelizumab (SHR-1210) is a humanized monoclonal antibody targeting the programmed death-1 (PD-1) receptor. Blockade of the PD-1/PD-L1 signaling pathway is a therapeutic strategy showing success in a wide variety of solid and hematological cancers.
Product Name : SHR-1210
Product Type : Large molecule
Upfront Cash : Not Applicable
September 07, 2022
Lead Product(s) : Camrelizumab,Rivoceranib
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : Elevar Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable