Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : FZ002-037
Therapeutic Area : Neurology
Study Phase : Phase I
Recipient : Guangzhou Fermion Technology
Deal Size : Undisclosed
Deal Type : Agreement
Fermion, Simcere Exclusive License for China’s First SSTR4 Agonist
Details : Under the agreement, Simcere will gain exclusive rights to develop and commercialize FZ002-037 in Greater China. It is being evaluated for the treatment of Chronic Pain.
Product Name : FZ002-037
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 17, 2025
Lead Product(s) : FZ002-037
Therapeutic Area : Neurology
Highest Development Status : Phase I
Recipient : Guangzhou Fermion Technology
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : SIM0500
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : AbbVie Inc
Deal Size : $1,055.0 million
Deal Type : Licensing Agreement
AbbVie Pens $1B deal for Simcere’s Phase 1 T-Cell Engager
Details : Simcere has option to license agreement with Abbvie to develop SIM0500, an investigational new drug candidate. It is being evaluated in patients with relapsed or refractory multiple myeloma.
Product Name : SIM0500
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
January 13, 2025
Lead Product(s) : SIM0500
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : AbbVie Inc
Deal Size : $1,055.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Edaravone,Dexborneol
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Simcere’s Sanbexin® Approved in China for Acute Ischemic Stroke
Details : Sanbexin (a combination of edaravone and dexborneol) is a small molecule, sublingual tablet, which is being evaluated for the treatment of acute ischemic stroke.
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Not Applicable
December 04, 2024
Lead Product(s) : Edaravone,Dexborneol
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Edaravone,Dexborneol
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Sanbexin Sublingual Tablets Receive Breakthrough Therapy Designation from FDA
Details : Sanbexin (a combination of edaravone and dexborneol) is a small molecule, sublingual tablet, which is being evaluated for the treatment of acute ischemic stroke.
Product Name : Sanbexin
Product Type : Small molecule
Upfront Cash : Not Applicable
September 05, 2024
Lead Product(s) : Edaravone,Dexborneol
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cetuximab,Irinotecan Hydrochloride,Calcium Folinate
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Simcere Zaiming Announce Approval of Cetuximab Beta in China by the NMPA
Details : Enlituo (cetuximab beta) is a EGFR inhibitor indicated in combination with the FOLFIRI regimen as a first-line treatment for RAS/BRAF wild-type metastatic colorectal cancer (mCRC).
Product Name : Enlituo
Product Type : Large molecule
Upfront Cash : Not Applicable
June 26, 2024
Lead Product(s) : Cetuximab,Irinotecan Hydrochloride,Calcium Folinate
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Edaravone,Dexborneol
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Neurodawn Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Findings of a Phase III Clinical Study of Sanbexin® Sublingual Tablets Published in JAMA
Details : Sanbexin (a combination of edaravone and dexborneol) is a small molecule, sublingual tablet, which is being evaluated for the treatment of acute ischemic stroke.
Product Name : Sanbexin
Product Type : Small molecule
Upfront Cash : Not Applicable
February 20, 2024
Lead Product(s) : Edaravone,Dexborneol
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Neurodawn Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Rademikibart
Therapeutic Area : Dermatology
Study Phase : Phase III
Recipient : Connect Biopharma
Deal Size : $141.0 million
Deal Type : Licensing Agreement
Details : Under the agreement, Simcere will develop and commercialize Connect Biopharma’s CBP-201 (rademikibart), a human monoclonal antibody against IL-4Rα, in Greater China.
Product Name : CBP-201
Product Type : Large molecule
Upfront Cash : $21.0 million
November 21, 2023
Lead Product(s) : Rademikibart
Therapeutic Area : Dermatology
Highest Development Status : Phase III
Recipient : Connect Biopharma
Deal Size : $141.0 million
Deal Type : Licensing Agreement
Details : The agreement aims to establish a mutually beneficial partnership that will advance scientific research and create new treatment options for patients with cancer, autoimmune and CNS diseases.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
June 12, 2023
Lead Product(s) : SIM0235,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the agreement, MSD will supply KEYTRUDA and collaborate with Simcere to evaluate the combination of SIM0235, a potential first-in-class humanized anti-TNFR2 mAb, and MSD's anti-PD-1 therapy, KEYTRUDA® (pembrolizumab), in patients with advanced sol...
Product Name : SIM0235
Product Type : Cytotoxic Drug
Upfront Cash : Undisclosed
March 14, 2023
Lead Product(s) : SIM0235,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : SSD8432,Ritonavir
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : XIANNUOXIN is a combination packaged drug of a small molecule anti- SARS-CoV-2 drug candidate SSD8432 and Ritonavir, this candidate is targeted 3CL protease which is essential for SARS-CoV-2 viral replication.
Product Name : Xiannuoxin
Product Type : Small molecule
Upfront Cash : Not Applicable
December 20, 2022
Lead Product(s) : SSD8432,Ritonavir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable