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Find Clinical Drug Pipeline Developments & Deals for JNT-517

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmaconex 2024
                          Not Confirmed
                          Pharmaconex 2024
                          Not Confirmed

                          Details : Through the acquisition, Otsuka will leverage Jana pipelines, which include JNT-517 an allosteric small molecule inhibitor of SLC6A19. It is being evaluated for the treatment of phenylketonuria.

                          Product Name : JNT-517

                          Product Type : Small molecule

                          Upfront Cash : $800.0 million

                          August 01, 2024

                          Lead Product(s) : JNT-517

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Partner/Sponsor/Collaborator : Otsuka Pharmaceutical

                          Deal Size : $1,125.0 million

                          Deal Type : Acquisition

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                          02

                          Pharmaconex 2024
                          Not Confirmed
                          Pharmaconex 2024
                          Not Confirmed

                          Details : JNT-517 is a, oral small-molecule, phenylalanine (Phe) transporter SLC6A19 inhibitor, a potential therapy used to treat PKU, regardless of age or genotype. JNT-517 acts at a novel, cryptic allosteric site...

                          Product Name : JNT-517

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 06, 2023

                          Lead Product(s) : JNT-517

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : IND Enabling

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmaconex 2024
                          Not Confirmed
                          Pharmaconex 2024
                          Not Confirmed

                          Lead Product(s) : JNT-517

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I

                          Partner/Sponsor/Collaborator : Bain Capital Life Sciences

                          Deal Size : $107.0 million

                          Deal Type : Series C Financing

                          Details : The proceeds from the funding will be used to progress the company’s lead program JNT-517 in phenylketonuria (PKU), a rare genetic metabolic disease, through a clinical proof-of-concept (POC) study, and...

                          Product Name : JNT-517

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          November 15, 2022

                          Lead Product(s) : JNT-517

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I

                          Partner/Sponsor/Collaborator : Bain Capital Life Sciences

                          Deal Size : $107.0 million

                          Deal Type : Series C Financing

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                          04

                          Pharmaconex 2024
                          Not Confirmed
                          Pharmaconex 2024
                          Not Confirmed

                          Details : JNT-517, is a small molecule, allosteric inhibitor of SLC6A19, a metabolite transporter responsible for reabsorption of phenylalanine (Phe) in the kidney.

                          Product Name : JNT-517

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 08, 2022

                          Lead Product(s) : JNT-517

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Preclinical

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharmaconex 2024
                          Not Confirmed
                          Pharmaconex 2024
                          Not Confirmed

                          Details : Discovery of JNT-517, which targets SLC6A19, is based on Jnana’s pioneering research and was enabled by RAPID, company’s high-throughput screening-enabled chemoproteomic platform for treatment of PKU ...

                          Product Name : JNT-517

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          February 23, 2022

                          Lead Product(s) : JNT-517

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : IND Enabling

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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