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Find Clinical Drug Pipeline Developments & Deals by Johnson & Johnson
Details :
Darzalex (daratumumab) a CD38 inhibitor, being evaluated in combination with bortezomib, lenalidomide, dexamethasone for the treatment of newly diagnosed multiple myeloma.
Details :
Darzalex Faspro (daratumumab) is a CD38 inhibitor antibody drug candidate, which is currently being evaluated in combination for the treatment of patients with newly diagnosed multiple myeloma.
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Yuvanci (macitentan, tadalafil) is an FDC available as a film coated tablet, for the treatment of pulmonary arterial hypertension in adults, works by inhibiting endothelin receptor & PDE5 inhibitor.
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Talvey (talquetamab) is a CD3 receptor binder in combination with daratumumab antibody drug administered via subcutaneous injection for relapsed or refractory multiple myeloma.
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Through the license agreement, AC Immune is investigating active immunotherapy candidate JNJ-2056 (ACI-35.030) to treat patients suffering from preclinical (pre-symptomatic) Alzheimer’s disease.
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The funds will advance the development of ONL1204 Ophthalmic Solution by initiating a Phase 2 global study for treating GA associated with dry age-related macular degeneration.
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Rybrevant (amivantamab) in combination with Lazcluze (lazertinib) and dexamethasone reduces infusion-related reactions in patients with EGFR-mutated non-small cell lung cancer.
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JNJ-80202135 (nipocalimab) is an investigational monoclonal antibody that aims to selectively block FcRn. It is being evaluated for the treatment of generalized myasthenia gravis.
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The agreement aims to commercialize its Bmab 1200, a proposed biosimilar to Stelara and a monoclonal antibody medication, in Europe, the United Kingdom (UK), Canada, and Japan.
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Rybrevant (amivantamab) is an EGFR-MET bispecific antibody, being evaluated in combination with chemotherapy for the treatment of previously untreated EGFR exon 20 insertion mutation-positive NSCLC.