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    [{"orgOrder":0,"company":"JW Therapeutics","sponsor":"CR-CP Life Science Fund","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Cell and Gene therapy","year":"2020","type":"Series B Financing","leadProduct":"JWCAR029","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"JW Therapeutics","amount2":0.10000000000000001,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"JW Therapeutics \/ CR-CP Life Science Fund","highestDevelopmentStatusID":"8","companyTruncated":"JW Therapeutics \/ CR-CP Life Science Fund"},{"orgOrder":0,"company":"JW Therapeutics","sponsor":"JW Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"HONG KONG","productType":"Cell and Gene therapy","year":"2020","type":"Acquisition","leadProduct":"T-cell therapy","moa":"","graph1":"Oncology","graph2":"Discovery Platform","graph3":"JW 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    Find Clinical Drug Pipeline Developments & Deals by JW Therapeutics

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                            01

                            JW Therapeutics

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                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            JW Therapeutics Announces NMPA Approval of the sBLA for Carteyva in Mantle Cell Lymphoma

                            Details : Carteyva (relmacabtagene autoleucel) is an anti-CD19 CAR-T approved for the treatment of adult patients with relapsed or refractory Mantle Cell Lymphoma (r/r MCL).

                            Brand Name : Carteyva

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            August 27, 2024

                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            JW Therapeutics

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                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            JW Therapeutics Announces IND Approval for the Clinical Trial of Relma-cel in Patients with Moderately or Seve...

                            Details : Relma-cel (relmacabtagene autoleucel) is based on the same chimeric antigen receptor (CAR) construct, currently beinf investigated in patients with moderately or severely refractory systemic lupus erythematosus.

                            Brand Name : Relma-cel

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            April 10, 2023

                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

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                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            JW Therapeutics Announces Initiation of Clinical Study of Carteyva® in First-line Treatment in Patients with ...

                            Details : Carteyva® (relmacabtagene autoleucel) is an autologous anti-CD19 CAR-T cell immunotherapy, which has been approved for relapsed or refractory large B-cell lymphoma and refractory follicular lymphoma.

                            Brand Name : Carteyva

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            March 08, 2023

                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            JW Therapeutics

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                            Lead Product(s) : JWATM214

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            JW Therapeutics Announces Initiation of Clinical Study of JWATM214 in Patients with Advanced Hepatocellular Ca...

                            Details : JWATM214 is an autologous T-cell immunotherapy candidate drug targeting GPC-3 to delay T cell exhaustion, to achieve more durable and superior anti-tumor activity, potentially providing novel treatment for GPC-3-expressing advanced HCC patients.

                            Brand Name : JWATM214

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            February 28, 2023

                            Lead Product(s) : JWATM214

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            JW Therapeutics

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                            Lead Product(s) : TCR T-cell Therapy

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : 2Seventy Bio

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            2seventy Bio and JW Therapeutics Announce Strategic Partnership to Accelerate the Research and Development of ...

                            Details : The initial focus of the collaboration is 2seventy bio’s MAGE-A4 TCR program in solid tumors which is being developed as part of a collaboration with Regeneron. MAGE-A4 is a member of the MAGE family of cancer-testis antigens expressed in a number of s...

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            October 27, 2022

                            Lead Product(s) : TCR T-cell Therapy

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : 2Seventy Bio

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            JW Therapeutics Announces NMPA Approval of Relmacabtagene Autoleucel Injection in Patients with Relapsed or Re...

                            Details : Cohort B results showed that Carteyva® (relmacabtagene autoleucel) demonstrated very high rates of durable disease response (ORR)=100%, (CRR)=85.19% at month 3; ORR=92.58%, CRR=77.78% at month 6) and controllable CAR-T associated toxicities in patients ...

                            Brand Name : Carteyva

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            October 10, 2022

                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            JW Therapeutics

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                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            JW Therapeutics Announces IND Approval for the Clinical Trial of Carteyva® in Pediatric and Young Adult Patie...

                            Details : The approval of Carteyva (relmacabtagene autoleucel (relma-cel) injection), an autologous anti-CD19 CAR-T cell immunotherapy product is based on results of a RELIANCE study in treating pediatric and young adult patients with r/r B-ALL.

                            Brand Name : Carteyva

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            April 20, 2022

                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            JW Therapeutics

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                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            JW Therapeutics Announces Receipt of Breakthrough Therapy Designation for Carteyva® in Mantle Cell Lymphoma i...

                            Details : Breakthrough Therapy Designation was supported by results from clinical study of Carteyva (relmacabtagene autoleucel) in relapsed or refractory MCL (r/r MCL), which aimed to assess the efficacy and safety of Carteyva® in adults with r/r MCL in China.

                            Brand Name : Carteyva

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            April 03, 2022

                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            JW Therapeutics

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                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            JW Therapeutics Announces IND Approval for the Pivotal Clinical Trial of Carteyva® in Second-line Large B-Cel...

                            Details : Carteyva® (relmacabtagene autoleucel injection) also abbreviated as relma-cel,an autologous anti-CD19 CAR-T cell immunotherapy product, in the treatment of second-line large B-Cell lymphoma.

                            Brand Name : Carteyva

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            March 31, 2022

                            Lead Product(s) : Relmacabtagene Autoleucel

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

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                            10

                            JW Therapeutics

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                            Lead Product(s) : Autoleucel Relmacabtagen

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            JW Therapeutics Claims Approval of Autoleucel Relmacabtagen Injection in China

                            Details : China NMPA has approved an application for registration of a new drug autoleucel relmacabtagen for the treatment of adult patients with recurrent or refractory large B-cell lymphoma (r / r HCL) after two or more lines of systemic therapy.

                            Brand Name : JWCAR029

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            September 06, 2021

                            Lead Product(s) : Autoleucel Relmacabtagen

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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