[{"orgOrder":0,"company":"Kaken Pharmaceuticals","sponsor":"Johnson & Johnson","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"JAPAN","productType":"Other Small Molecule","year":"2024","type":"Licensing Agreement","leadProduct":"KP-723","moa":"Undisclosed","graph1":"Dermatology","graph2":"Preclinical","graph3":"Kaken Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Kaken Pharmaceuticals \/ Johnson & Johnson","highestDevelopmentStatusID":"4","companyTruncated":"Kaken Pharmaceuticals \/ Johnson & Johnson"},{"orgOrder":0,"company":"Kaken Pharmaceuticals","sponsor":"Fresh Tracks Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"JAPAN","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Sofpironium Bromide","moa":"M3 receptor","graph1":"Dermatology","graph2":"Approved FDF","graph3":"Kaken Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Gel","sponsorNew":"Kaken Pharmaceuticals \/ Fresh Tracks Therapeutics","highestDevelopmentStatusID":"15","companyTruncated":"Kaken Pharmaceuticals \/ Fresh Tracks Therapeutics"},{"orgOrder":0,"company":"Kaken Pharmaceuticals","sponsor":"Whitehawk Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibiotic","year":"2025","type":"Divestment","leadProduct":"Sirolimus Protein-bound Particle","moa":"mTOR","graph1":"Oncology","graph2":"Approved FDF","graph3":"Kaken Pharmaceuticals","amount2":0.10000000000000001,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0.10000000000000001,"dosageForm":"Intravenous Infusion","sponsorNew":"Kaken Pharmaceuticals \/ Kaken Pharmaceuticals","highestDevelopmentStatusID":"15","companyTruncated":"Kaken Pharmaceuticals \/ Kaken Pharmaceuticals"},{"orgOrder":0,"company":"Kaken Pharmaceuticals","sponsor":"KalVista Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Licensing Agreement","leadProduct":"Sebetralstat","moa":"Plasma kallikrein","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Kaken Pharmaceuticals","amount2":0.02,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0.02,"dosageForm":"Oral Tablet","sponsorNew":"Kaken Pharmaceuticals \/ Kaken Pharmaceuticals","highestDevelopmentStatusID":"10","companyTruncated":"Kaken Pharmaceuticals \/ Kaken Pharmaceuticals"}]

Find Clinical Drug Pipeline Developments & Deals by Kaken Pharmaceuticals

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                          Top Deals by Deal Size (USD bn)

                          01

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : Under the licensing agreement, Kaken will holds the rights of KVD900 (sebetralstat) in Japan. It is being evaluated for the treatment of hereditary angioedema.

                          Product Name : KVD900

                          Product Type : Other Small Molecule

                          Upfront Cash : $11.0 million

                          April 08, 2025

                          Lead Product(s) : Sebetralstat

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Recipient : KalVista Pharmaceuticals

                          Deal Size : $22.0 million

                          Deal Type : Licensing Agreement

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                          02

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : Through the divestment, Kaken assumes ownership of FYARRO (sirolimus protein-bound particles for injectable suspension) used to treat adults with malignant perivascular epithelioid cell tumor.

                          Product Name : Fyarro

                          Product Type : Antibiotic

                          Upfront Cash : $100.0 million

                          March 26, 2025

                          Lead Product(s) : Sirolimus Protein-bound Particle

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Recipient : Whitehawk Therapeutics

                          Deal Size : $100.0 million

                          Deal Type : Divestment

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                          03

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : Johnson gains an exclusive license to Kaken’s STAT6 program, including lead candidate KP-723, a preclinical STAT6 inhibitor, for autoimmune and allergic diseases, including atopic dermatitis.

                          Product Name : KP-723

                          Product Type : Other Small Molecule

                          Upfront Cash : $30.0 million

                          December 26, 2024

                          Lead Product(s) : KP-723

                          Therapeutic Area : Dermatology

                          Highest Development Status : Preclinical

                          Sponsor : Johnson & Johnson

                          Deal Size : $1,247.5 million

                          Deal Type : Licensing Agreement

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                          04

                          Cophex
                          Not Confirmed
                          Cophex
                          Not Confirmed

                          Details : Sofpironium bromide gel was deemed to be safe and well tolerated in this study, as well as in the accompanying 52-week long-term safety extension study in Japan. Japan is the first country to approve sofpironium bromide with commercial launch expected la...

                          Product Name : Ecclock

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 25, 2020

                          Lead Product(s) : Sofpironium Bromide

                          Therapeutic Area : Dermatology

                          Highest Development Status : Approved FDF

                          Sponsor : Fresh Tracks Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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