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    [{"orgOrder":0,"company":"KaliVir Immunotherapeutics","sponsor":"Astellas Pharma","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2020","type":"Collaboration","leadProduct":"VET2-L2","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"KaliVir Immunotherapeutics","amount2":0.63,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.63,"dosageForm":"","sponsorNew":"KaliVir Immunotherapeutics \/ Astellas","highestDevelopmentStatusID":"4","companyTruncated":"KaliVir Immunotherapeutics \/ Astellas"},{"orgOrder":0,"company":"KaliVir Immunotherapeutics","sponsor":"F. Hoffmann-La Roche","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Licensing Agreement","leadProduct":"VET-ROG1","moa":"","graph1":"Oncology","graph2":"Discovery","graph3":"KaliVir Immunotherapeutics","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"KaliVir Immunotherapeutics \/ Roche","highestDevelopmentStatusID":"2","companyTruncated":"KaliVir Immunotherapeutics \/ Roche"},{"orgOrder":0,"company":"KaliVir Immunotherapeutics","sponsor":"SIGA Technologies","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Collaboration","leadProduct":"Tecovirimat","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"KaliVir Immunotherapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"KaliVir Immunotherapeutics \/ KaliVir Immunotherapeutics","highestDevelopmentStatusID":"4","companyTruncated":"KaliVir Immunotherapeutics \/ KaliVir Immunotherapeutics"},{"orgOrder":0,"company":"KaliVir Immunotherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Vaccine","year":"2023","type":"Not Applicable","leadProduct":"ASP1012","moa":"","graph1":"Oncology","graph2":"IND Enabling","graph3":"KaliVir Immunotherapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injection","sponsorNew":"KaliVir Immunotherapeutics \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"KaliVir Immunotherapeutics \/ Not Applicable"},{"orgOrder":0,"company":"KaliVir Immunotherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Pembrolizumab","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"KaliVir Immunotherapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"KaliVir Immunotherapeutics \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"KaliVir Immunotherapeutics \/ Not Applicable"},{"orgOrder":0,"company":"KaliVir Immunotherapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Pembrolizumab","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"KaliVir Immunotherapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"KaliVir Immunotherapeutics \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"KaliVir Immunotherapeutics \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals by KaliVir Immunotherapeutics

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                            01

                            KaliVir Immunotherapeutics

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                            Lead Product(s) : VET3-TGI,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            KaliVir Doses First Patient in Trial of VET3-TGI For Advanced Solid Tumors

                            Details : VET3-TGI is an oncolytic immunotherapy, given intratumoraly, that acts as a TGF beta-1 inhibitor & IL-12 stimulator, is being studied in combination with pembrolizumab for treating solid tumors.

                            Brand Name : VET3-TGI

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 08, 2024

                            Lead Product(s) : VET3-TGI,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            KaliVir Immunotherapeutics

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                            Lead Product(s) : VET3-TGI,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            KaliVir Immunotherapeutics Gets FDA Clearance for VET3-TGI Oncolytic Immunotherapy

                            Details : VET3-TGI is an oncolytic immunotherapy, given intratumoraly, that acts as a TGF beta-1 inhibitor & IL-12 stimulator, is being studied in combination with pembrolizumab for treating solid tumors.

                            Brand Name : VET3-TGI

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            July 01, 2024

                            Lead Product(s) : VET3-TGI,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            KaliVir Immunotherapeutics

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                            Lead Product(s) : ASP1012

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            KaliVir Immunotherapeutics Announces FDA Clearance of Investigational New Drug (IND) for Systemic Oncolytic Vi...

                            Details : ASP1012 (formerly named VET2-L2) is a systemic oncolytic vaccinia virus therapy in which the virus is delivered intravenously and expresses Leptin-IL2 fusion protein as a therapeutic payload. The trial is expected to begin in Q1 2024.

                            Brand Name : ASP1012

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            October 24, 2023

                            Lead Product(s) : ASP1012

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            KaliVir Immunotherapeutics

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                            Lead Product(s) : Vaccinia-based Cancer Therapy,Tecovirimat

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : SIGA Technologies

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            SIGA Announces Oncology Collaboration with KaliVir Immunotherapeutics

                            Details : TPOXX is a powerful antiviral drug to vaccinia and allows the safe use of higher doses of vaccinia vectors, there is also the potential it could increase immunotherapeutic outcomes.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            July 15, 2022

                            Lead Product(s) : Vaccinia-based Cancer Therapy,Tecovirimat

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : SIGA Technologies

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            05

                            KaliVir Immunotherapeutics

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                            Lead Product(s) : VET-ROG1

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            KaliVir Immunotherapeutics Enters into Global Exclusive Licensing Agreement with Roche for Novel Oncolytic Vir...

                            Details : Under the terms of the agreement, KaliVir will generate oncolytic vaccinia virus product candidates derived from the company's VETTM platform, including VET-ROG1 expressing Roche proprietary therapeutic transgenes.

                            Brand Name : VET-ROG1

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            May 23, 2022

                            Lead Product(s) : VET-ROG1

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Sponsor : F. Hoffmann-La Roche

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            KaliVir Immunotherapeutics

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                            Lead Product(s) : VET2-L2

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Astellas Pharma

                            Deal Size : $634.0 million

                            Deal Type : Collaboration

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                            KaliVir Immunotherapeutics and Astellas Ink Licensing Agreement for Development and Commercialization of VET2-...

                            Details : Under the terms of the agreement, Astellas will pay to KaliVir up to US$56 million in the form of an upfront payment and other payments to support research and preclinical activities related to VET2-L2 and the Second Product.

                            Brand Name : VET2-L2

                            Molecule Type : Large molecule

                            Upfront Cash : $56.0 million

                            December 07, 2020

                            Lead Product(s) : VET2-L2

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Astellas Pharma

                            Deal Size : $634.0 million

                            Deal Type : Collaboration

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