Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Navtemadlin
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : Tempus
Deal Size : Undisclosed
Deal Type : Collaboration
Tempus Announces Companion Diagnostic Collaboration with Kartos Therapeutics
Details : Kartos is collaborating with Tempus to use the xT assay, a 648-gene panel, to identify patients with TP53 wild-type (TP53WT) Merkel cell carcinoma (MCC) who may benefit from treatment with KRT-232 (navtemadlin, a small molecule MDM2 inhibitor).
Brand Name : KRT-232
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 06, 2022
Lead Product(s) : Navtemadlin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : Tempus
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Navtemadlin
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Illumina
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The initial focus of the collaboration will be the co-development of multiple CDx claims in blood cancers for Kartos’ KRT-232, a potent and selective oral MDM2 inhibitor that activates p53 to drive tumor cell death in TP53 wild-type cancers.
Brand Name : KRT-232
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 24, 2021
Lead Product(s) : Navtemadlin
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Illumina
Deal Size : Undisclosed
Deal Type : Collaboration
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