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Find Clinical Drug Pipeline Developments & Deals for KBP-5074

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                          01

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The Phase 2b clinical trial met its primary endpoint, with KBP-5074 demonstrating a clinically and statistically significant improvement in systolic blood pressure (SBP) from baseline to day 84 in Stage 3b/4 CKD patients with uncontrolled hypertension.

                          Brand Name : KBP-5074

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 07, 2020

                          Lead Product(s) : KBP-5074

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The upcoming data to be presented at the American Society of Nephrology (ASN) Annual Meeting showcases a pre-clinical study investigating the effect of KBP-5074 on aldosterone-mediated renal injury in the uninephrectomized SD rat CKD model.

                          Brand Name : KBP-5074

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 22, 2020

                          Lead Product(s) : KBP-5074

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Sponsor : Labcorp Drug Development

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : BLOCK-CKD is a Phase 2b, international, multicenter, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of KBP-5074, on top of current therapy, in patients with Stage 3B/4 CKD and uncontrolled hypertens...

                          Brand Name : KBP-5074

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 29, 2020

                          Lead Product(s) : KBP-5074

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Sponsor : Labcorp Drug Development

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Single doses of 0.5 mg KBP-5074 were generally well tolerated in patients with severe CKD, with or without hemodialysis . Overall drug exposure was significantly lower in hemodialyzed patients vs. non-hemodialyzed patients.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 21, 2020

                          Lead Product(s) : KBP-5074

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Sponsor : Labcorp Drug Development

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : BLOCK CKD is a randomized, double-blind, placebo-controlled, multi-center study to assess the efficacy, safety, and pharmacokinetics of KBP-5074 in patients with moderate-to-severe CKD and uncontrolled hypertension.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 20, 2020

                          Lead Product(s) : KBP-5074

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Sponsor : Labcorp Drug Development

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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