Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : KBP-5074
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The Phase 2b clinical trial met its primary endpoint, with KBP-5074 demonstrating a clinically and statistically significant improvement in systolic blood pressure (SBP) from baseline to day 84 in Stage 3b/4 CKD patients with uncontrolled hypertension.
Brand Name : KBP-5074
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 07, 2020
Lead Product(s) : KBP-5074
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : KBP-5074
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Labcorp Drug Development
Deal Size : Not Applicable
Deal Type : Not Applicable
KBP Biosciences Announces Data Presentation at the American Society of Nephrology Annual Meeting
Details : The upcoming data to be presented at the American Society of Nephrology (ASN) Annual Meeting showcases a pre-clinical study investigating the effect of KBP-5074 on aldosterone-mediated renal injury in the uninephrectomized SD rat CKD model.
Brand Name : KBP-5074
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 22, 2020
Lead Product(s) : KBP-5074
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Labcorp Drug Development
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : KBP-5074
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Labcorp Drug Development
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BLOCK-CKD is a Phase 2b, international, multicenter, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of KBP-5074, on top of current therapy, in patients with Stage 3B/4 CKD and uncontrolled hypertens...
Brand Name : KBP-5074
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 29, 2020
Lead Product(s) : KBP-5074
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Labcorp Drug Development
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : KBP-5074
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Labcorp Drug Development
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Single doses of 0.5 mg KBP-5074 were generally well tolerated in patients with severe CKD, with or without hemodialysis . Overall drug exposure was significantly lower in hemodialyzed patients vs. non-hemodialyzed patients.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 21, 2020
Lead Product(s) : KBP-5074
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Labcorp Drug Development
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : KBP-5074
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Labcorp Drug Development
Deal Size : Not Applicable
Deal Type : Not Applicable
KBP Biosciences Completes Enrollment of BLOCK CKD Phase 2b Study of KBP-5074
Details : BLOCK CKD is a randomized, double-blind, placebo-controlled, multi-center study to assess the efficacy, safety, and pharmacokinetics of KBP-5074 in patients with moderate-to-severe CKD and uncontrolled hypertension.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 20, 2020
Lead Product(s) : KBP-5074
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Labcorp Drug Development
Deal Size : Not Applicable
Deal Type : Not Applicable
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