[{"orgOrder":0,"company":"KeifeRx","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Series A Financing","leadProduct":"Nilotinib","moa":"ABL1 gene","graph1":"Neurology","graph2":"Phase II","graph3":"KeifeRx","amount2":0.01,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0.01,"dosageForm":"Capsule","sponsorNew":"KeifeRx \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"KeifeRx \/ Undisclosed"},{"orgOrder":0,"company":"KeifeRx","sponsor":"KeifeRx","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Licensing Agreement","leadProduct":"KFRX03","moa":"","graph1":"Neurology","graph2":"IND Enabling","graph3":"KeifeRx","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"KeifeRx \/ KeifeRx","highestDevelopmentStatusID":"5","companyTruncated":"KeifeRx \/ KeifeRx"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Under the agreement, KeifeRx will develop novel TKI chemical entities for treating neurodegenerative, neuroinflammatory, and mast cell-associated diseases, including KFRX03 and KFRX04.

                          Brand Name : KFRX03

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          January 08, 2024

                          Lead Product(s) : KFRX03

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Recipient : Georgetown University

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Proceeds from the financing will advance pipeline of optimized, low dose, orally delivered tyrosine kinase inhibitors including Nilotinib BE for the treatment of multiple neurodegenerative diseases.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          December 08, 2021

                          Lead Product(s) : Nilotinib

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : $6.0 million

                          Deal Type : Series A Financing

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