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    [{"orgOrder":0,"company":"Orexo","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Promising Results From Human PK Study Assessing Novel Ketorolac Formulations for Treatment of Pain","therapeuticArea":"Neurology","highestDevelopmentStatus":"Phase I","country":"SWEDEN","productType":"Small molecule","productStatus":"Approved","date":"January 2020","year":"2020","type":"Not Applicable","leadProduct":"Ketorolac Trometamol","moa":"COX","url1":"","url2":"","graph1":"Neurology","graph2":"Phase I","graph3":"Orexo","amount2":0,"therapeuticAreaNew":"Neurology","highestDevelopmentStatusNew":"Phase I","highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","productSubType":"","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Orexo \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Orexo \/ Not Applicable"},{"orgOrder":0,"company":"Neumentum","sponsor":"Nuance Biotech","pharmaFlowCategory":"D","amount":"$53.0 million","upfrontCash":"$3.0 million","newsHeadline":"Neumentum and Nuance Biotech Enter into Licensing Agreement for NTM-001 (ketorolac for IV infusion) in China","therapeuticArea":"Neurology","highestDevelopmentStatus":"Phase III","country":"","productType":"Small molecule","productStatus":"Approved","date":"October 2020","year":"2020","type":"Licensing Agreement","leadProduct":"Ketorolac Trometamol","moa":"COX","url1":"","url2":"","graph1":"Neurology","graph2":"Phase III","graph3":"Neumentum","amount2":0.050000000000000003,"therapeuticAreaNew":"Neurology","highestDevelopmentStatusNew":"Phase III","highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","productSubType":"Small molecule","amount2New":0.050000000000000003,"dosageForm":"Intravenous Infusion","sponsorNew":"Neumentum \/ Nuance Biotech","highestDevelopmentStatusID":"10","companyTruncated":"Neumentum \/ Nuance Biotech"},{"orgOrder":0,"company":"Neumentum","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Neumentum to Present New Data for Drug Candidate NTM-001 at the 2020 ASHP Midyear Clinical Meeting and Exhibition","therapeuticArea":"Neurology","highestDevelopmentStatus":"Phase III","country":"","productType":"Small molecule","productStatus":"Approved","date":"December 2020","year":"2020","type":"Not Applicable","leadProduct":"Ketorolac Trometamol","moa":"COX","url1":"","url2":"","graph1":"Neurology","graph2":"Phase III","graph3":"Neumentum","amount2":0,"therapeuticAreaNew":"Neurology","highestDevelopmentStatusNew":"Phase III","highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","productSubType":"Small molecule","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Neumentum \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Neumentum \/ Not Applicable"},{"orgOrder":0,"company":"Nemera","sponsor":"Ache Laboratorios Farmaceuticos SA","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Nemera\u2019s Preservative-Free Multi-Dose Eyedropper Approved in Brazil for Ach\u00e9\u2019s NSAID\u2019s and Dry Eye Formulations","therapeuticArea":"Ophthalmology","highestDevelopmentStatus":"Approved","country":"","productType":"Small molecule","productStatus":"Approved","date":"May 2021","year":"2021","type":"Not Applicable","leadProduct":"Ketorolac Trometamol","moa":"","url1":"","url2":"","graph1":"Ophthalmology","graph2":"Approved","graph3":"Nemera","amount2":0,"therapeuticAreaNew":"Ophthalmology","highestDevelopmentStatusNew":"Approved","highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Ophthalmology","productSubType":"","amount2New":0,"dosageForm":"Eye Drop","sponsorNew":"Nemera \/ Ache","highestDevelopmentStatusID":"12","companyTruncated":"Nemera \/ Ache"},{"orgOrder":0,"company":"Omeros","sponsor":"Rayner Surgical Group Limited","pharmaFlowCategory":"D","amount":"$1,000.0 million","upfrontCash":"$125.0 million","newsHeadline":"Omeros Announces Agreement to Sell OMIDRIA\u00ae Franchise to Rayner Surgical in a Transaction Valued in Excess of $1 Billion","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","highestDevelopmentStatus":"Approved","country":"","productType":"Small molecule","productStatus":"Approved","date":"December 2021","year":"2021","type":"Agreement","leadProduct":"Phenylephrine Hydrochloride","moa":"Adrenergic receptor alpha-1","url1":"","url2":"","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Approved","graph3":"Omeros","amount2":1,"therapeuticAreaNew":"Trauma (Emergency, Injury, Surgery)","highestDevelopmentStatusNew":"Approved","highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Trauma","productSubType":"","amount2New":1,"dosageForm":"Intraocular Solution","sponsorNew":"Omeros \/ 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Announce the Launch Ketorolac Tromethamine Tablets USP, 10 mg in the U.S. Market","therapeuticArea":"Neurology","highestDevelopmentStatus":"Approved","country":"","productType":"Small molecule","productStatus":"Approved","date":"May 2022","year":"2022","type":"Not Applicable","leadProduct":"Ketorolac Trometamol","moa":"","url1":"","url2":"","graph1":"Neurology","graph2":"Approved","graph3":"Dr. Reddy\\\\\\'s Laboratories","amount2":0,"therapeuticAreaNew":"Neurology","highestDevelopmentStatusNew":"Approved","highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","productSubType":"","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Dr. Reddy\\\\\\'s Laboratories \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Dr. Reddy\\\\\\'s Laboratories \/ Not Applicable"},{"orgOrder":0,"company":"Nuance Pharma","sponsor":"Neumentum","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Nuance Pharma 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Valued in Excess of $1 Billion","therapeuticArea":"Ophthalmology","highestDevelopmentStatus":"Approved","country":"","productType":"Small molecule","productStatus":"Approved","date":"December 2021","year":"2021","type":"Divestment","leadProduct":"Phenylephrine Hydrochloride","moa":"","url1":"","url2":"","graph1":"Ophthalmology","graph2":"Approved","graph3":"Omeros","amount2":1.3300000000000001,"therapeuticAreaNew":"Ophthalmology","highestDevelopmentStatusNew":"Approved","highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Ophthalmology","productSubType":"","amount2New":1.3300000000000001,"dosageForm":"Solution\/Drops","sponsorNew":"Omeros \/ Rayner","highestDevelopmentStatusID":"12","companyTruncated":"Omeros \/ Rayner"},{"orgOrder":0,"company":"Omeros","sponsor":"Rayner","pharmaFlowCategory":"D","amount":"$1,326 million","upfrontCash":"$126.0 million","newsHeadline":"Omeros Completes Sale of OMIDRIA\u00ae Franchise to Rayner Surgical","therapeuticArea":"Ophthalmology","highestDevelopmentStatus":"Approved","country":"","productType":"Small molecule","productStatus":"Approved","date":"December 2021","year":"2021","type":"Divestment","leadProduct":"Phenylephrine Hydrochloride","moa":"","url1":"","url2":"","graph1":"Ophthalmology","graph2":"Approved","graph3":"Omeros","amount2":1.3300000000000001,"therapeuticAreaNew":"Ophthalmology","highestDevelopmentStatusNew":"Approved","highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Ophthalmology","productSubType":"","amount2New":1.3300000000000001,"dosageForm":"Solution\/Drops","sponsorNew":"Omeros \/ Rayner","highestDevelopmentStatusID":"12","companyTruncated":"Omeros \/ Rayner"},{"orgOrder":0,"company":"Concentric Analgesics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Concentric Analgesics Data Shows Durable Pain Relief and Earlier Opioid Cessation","therapeuticArea":"Neurology","highestDevelopmentStatus":"Phase II","country":"","productType":"Small molecule","productStatus":"New Molecular Entity","date":"August 2024","year":"2024","type":"Not Applicable","leadProduct":"Vocacapsaicin","moa":"","url1":"","url2":"","graph1":"Technology","graph2":"","graph3":"Concentric Analgesics","amount2":0,"therapeuticAreaNew":"Technology","highestDevelopmentStatusNew":"","highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","productSubType":"","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Concentric Analgesics \/ Not Applicable","highestDevelopmentStatusID":"13","companyTruncated":"Concentric Analgesics \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals for Ketorolac

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                            01

                            Dr. Reddy\'s Laboratories

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                            CPhI Worldwide, Milan
                            Booth #24A41
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                            Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

                            Lead Product(s) : Ketorolac Trometamol

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Dr. Reddy's Laboratories and Senores Pharmaceuticals, Inc. Announce the Launch Ketorolac Tromethamine Tablets ...

                            Details : Ketorolac Tromethamine Tablets USP, 10 mg, is a nonsteroidal anti-inflammatory drug (“NSAID”) indicated for the short-term (up to 5 days in adults) management of moderately severe acute pain that requires analgesia at the opioid level and only as con...

                            Brand Name : Ketorolac Tromethamine-Generic

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 24, 2022

                            Lead Product(s) : Ketorolac Trometamol

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Concentric Analgesics

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                            Discovery on Target
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                            Concentric Analgesics

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                            Discovery on Target
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                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Vocacapsaicin,Ketorolac Trometamol,Paracetamol

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Concentric Analgesics Data Shows Durable Pain Relief and Earlier Opioid Cessation

                            Details : CA-008 (vocacapsaicin) a water-soluble prodrug of capsaicin, rapidly releases capsaicin at surgical site triggering the activation of the TRPV1 receptor on pain-specific nerves, producing analgesia.

                            Brand Name : CA-008

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 06, 2024

                            Lead Product(s) : Vocacapsaicin,Ketorolac Trometamol,Paracetamol

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Omeros

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                            Discovery on Target
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                            Omeros

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                            Discovery on Target
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                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved

                            Sponsor : Rayner

                            Deal Size : $1,326 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            Omeros Corporation Receives $200 Million Milestone Payment from Rayner Surgical

                            Details : Under the terms of the Agreement, the royalty rate applicable to U.S. net sales of OMIDRIA (phenylephrine) decreased from 50 percent to 30 percent of U.S. net sales following achievement of the Milestone Event.

                            Brand Name : Omidria

                            Molecule Type : Small molecule

                            Upfront Cash : $126.0 million

                            February 06, 2023

                            Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved

                            Sponsor : Rayner

                            Deal Size : $1,326 million

                            Deal Type : Divestment

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                            04

                            Omeros

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                            Discovery on Target
                            Not Confirmed

                            Omeros

                            U.S.A arrow
                            Discovery on Target
                            Not Confirmed
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                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : DRI Healthcare Acquisitions

                            Deal Size : $188.4 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Omeros Corporation Announces Royalty Monetization Transaction with DRI Healthcare Trust

                            Details : Under the Royalty Purchase Agreement, DRI is entitled to royalties on net sales of OMIDRIA (having phenylephrine) received between September 1, 2022 and December 31, 2030, subject to annual caps.

                            Brand Name : Omidria

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 03, 2022

                            Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : DRI Healthcare Acquisitions

                            Deal Size : $188.4 million

                            Deal Type : Agreement

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                            05

                            Nuance Pharma

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                            Discovery on Target
                            Not Confirmed

                            Nuance Pharma

                            China arrow
                            Discovery on Target
                            Not Confirmed
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                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Ketorolac Trometamol

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Neumentum

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Nuance Pharma Announces the Completion of Dosing for All NTM-001 Phase 1 Clinical Study Participants in HKU Cl...

                            Details : Ketorolac (NTM-001) is a novel, alcohol-free formulation of ketorolac in a convenient, ready-to-use, pre-mixed bag for continuous 24 hours IV infusion, for the treatment of moderately severe acute pain requiring analgesia.

                            Brand Name : NTM-001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 26, 2022

                            Lead Product(s) : Ketorolac Trometamol

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Neumentum

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Concentric Analgesics

                            U.S.A arrow
                            Discovery on Target
                            Not Confirmed

                            Concentric Analgesics

                            U.S.A arrow
                            Discovery on Target
                            Not Confirmed
                            • fda
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                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Vocacapsaicin,Ketorolac Trometamol,Paracetamol

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Evolution Research Group

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Concentric Analgesics Forges Important Phase 3 Clinical Relationships for Vocacapsaicin, a Non-Opioid Pain The...

                            Details : The company has entered into a formal agreement with Evolution Research Group (ERG), a leading postsurgical pain clinical research site network in the U.S., to conduct its registration trials with CA-008 (vocacapsaicin).

                            Brand Name : CA-008

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            February 02, 2022

                            Lead Product(s) : Vocacapsaicin,Ketorolac Trometamol,Paracetamol

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Evolution Research Group

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            07

                            Concentric Analgesics

                            U.S.A arrow
                            Discovery on Target
                            Not Confirmed

                            Concentric Analgesics

                            U.S.A arrow
                            Discovery on Target
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Vocacapsaicin,Ketorolac Trometamol,Paracetamol

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : University of Rochester Medical Center

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Concentric Analgesics Forges Important Phase 3 Clinical Relationships for Vocacapsaicin, a Non-Opioid Pain The...

                            Details : URMC will participate in the vocacapsaicin Phase 3 clinical trials and develop innovative methods to capture vocacapsaicin’s benefit to patient recovery and rehabilitation.

                            Brand Name : CA-008

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            February 02, 2022

                            Lead Product(s) : Vocacapsaicin,Ketorolac Trometamol,Paracetamol

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : University of Rochester Medical Center

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            08

                            Concentric Analgesics

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                            Discovery on Target
                            Not Confirmed

                            Concentric Analgesics

                            U.S.A arrow
                            Discovery on Target
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Vocacapsaicin,Ketorolac Trometamol,Paracetamol

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : $20.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Concentric Analgesics Announces Completion of $20 Million Financing and Appoints Two New Board Members as it P...

                            Details : Concentric intends to use the proceeds from the financing to further fund Phase 3 development activities for vocacapsaicin, its lead therapeutic candidate for postsurgical pain.

                            Brand Name : CA-008

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            January 26, 2022

                            Lead Product(s) : Vocacapsaicin,Ketorolac Trometamol,Paracetamol

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : $20.0 million

                            Deal Type : Financing

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                            Omeros

                            U.S.A arrow
                            Discovery on Target
                            Not Confirmed

                            Omeros

                            U.S.A arrow
                            Discovery on Target
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved

                            Sponsor : Rayner

                            Deal Size : $1,326 million

                            Deal Type : Divestment

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                            Omeros Completes Sale of OMIDRIA® Franchise to Rayner Surgical

                            Details : As part of the agreement, Rayner will acquire the OMIDRIA (phenylephrine) commercial organization, including the OMIDRIA sales force. In addition, Rayner plans to expand the sales force in both the U.S. and ex-U.S.

                            Brand Name : Omidria

                            Molecule Type : Small molecule

                            Upfront Cash : $126.0 million

                            December 23, 2021

                            Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved

                            Sponsor : Rayner

                            Deal Size : $1,326 million

                            Deal Type : Divestment

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                            Omeros

                            U.S.A arrow
                            Discovery on Target
                            Not Confirmed

                            Omeros

                            U.S.A arrow
                            Discovery on Target
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Approved

                            Sponsor : Rayner Surgical Group Limited

                            Deal Size : $1,000.0 million

                            Deal Type : Agreement

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                            Omeros Announces Agreement to Sell OMIDRIA® Franchise to Rayner Surgical in a Transaction Valued in Excess of...

                            Details : As part of the agreement, Rayner will acquire the OMIDRIA commercial organization, including the OMIDRIA sales force. Rayner plans to expand the sales force in both the U.S. and ex-U.S., and further accelerating U.S. market growth of OMIDRIA.

                            Brand Name : Omidria

                            Molecule Type : Small molecule

                            Upfront Cash : $125.0 million

                            December 02, 2021

                            Lead Product(s) : Phenylephrine Hydrochloride,Ketorolac Trometamol

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Approved

                            Sponsor : Rayner Surgical Group Limited

                            Deal Size : $1,000.0 million

                            Deal Type : Agreement

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