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                          01

                          Lead Product(s) : AMX-818,Pembrolizumab

                          Therapeutic Area : Oncology

                          Study Phase : Phase I/ Phase II

                          Sponsor : Vir Biotechnology

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          Details : Through the license agreement, Vir Biotechnology will gain the rights of three clinical-stage masked TCEs, which include SAR446309 (AMX-818) for the treatment of HER2-mutated Breast Neoplasms.

                          Brand Name : SAR446309

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          September 09, 2024

                          Lead Product(s) : AMX-818,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Vir Biotechnology

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          Sanofi Company Banner

                          02

                          Lead Product(s) : AMX-818,Pembrolizumab

                          Therapeutic Area : Oncology

                          Study Phase : Phase I/ Phase II

                          Sponsor : Vir Biotechnology

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          Details : Through the license agreement, Vir Biotechnology will gain the rights of three clinical-stage masked TCEs, which include SAR446309 (AMX-818) for the treatment of HER2-mutated Breast Neoplasms.

                          Brand Name : SAR446309

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          August 01, 2024

                          Lead Product(s) : AMX-818,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Vir Biotechnology

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          Sanofi Company Banner

                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : VET3-TGI is an oncolytic immunotherapy, given intratumoraly, that acts as a TGF beta-1 inhibitor & IL-12 stimulator, is being studied in combination with pembrolizumab for treating solid tumors.

                          Brand Name : VET3-TGI

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 08, 2024

                          Lead Product(s) : VET3-TGI,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : KVA12123 is a VISTA inhibitor antibody, It is being evaluated in combination with keytruda for the treatment of patients with neoplasms including lung cancers.

                          Brand Name : KVA12123

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 08, 2024

                          Lead Product(s) : KVA12123,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : MK-4280A (favezelimab/pembrolizumab) is a IV infused LAG3/PD-1 inhibitor antibody, it is being evaluated for the treatment of PD-L1 Positive Microsatellite Stable Metastatic Colorectal Cancer.

                          Brand Name : MK-4280A

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 25, 2024

                          Lead Product(s) : Favezelimab,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Padcev (enfortumab vedotin), a nectin-4 inhibitor ADC in combination with keytruda, a PD-1 inhibitor. It is being evaluated for the treatment of locally advanced or metastatic urothelial cancer.

                          Brand Name : Padcev

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 24, 2024

                          Lead Product(s) : Enfortumab Vedotin,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Pfizer Inc

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The funding will support company’s ICT01, a pathogen-agnostic γ9δ2 T cell-activating monoclonal antibody, currently in a Phase I/IIa in various solid cancer and hematologic malignancy indications.

                          Brand Name : ICT01

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          August 29, 2024

                          Lead Product(s) : ICT01,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Bpifrance

                          Deal Size : $22.4 million

                          Deal Type : Funding

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                          08

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Padcev (enfortumab vedotin-ejfv), a nectin-4 inhibitor ADC in combination with Keytruda, a PD-1 inhibitoris approved for locally advanced or metastatic urothelial cancer.

                          Brand Name : Padcev

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 27, 2024

                          Lead Product(s) : Enfortumab Vedotin,Pembrolizumab,Cisplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Anktiva (nogapendekin alfa inbakicept-pmln) is a IL-15 receptor agonist, which is being evaluated in combination with AdHER2DC vaccine for the treatment of endometrial cancer.

                          Brand Name : Anktiva

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 06, 2024

                          Lead Product(s) : Nogapendekin Alfa Inbakicept,AdHER2DC,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : UV1 is a hTERT inhibitor, which is being evaluated in combination with pembrolizumab in patients for the treatment of metastatic or recurrent head and neck cancer.

                          Brand Name : UV1

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          August 05, 2024

                          Lead Product(s) : UV1,Pembrolizumab,Sargramostim

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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