Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : KIO-301
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Recipient : Accelagen
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : KIO-301 acts as a reversible 'photoswitch', specifically designed to restore the eyes' ability to perceive and interpret light in visually impaired patients with retinitis pigmentos.
Brand Name : KIO-301
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 14, 2023
Lead Product(s) : KIO-301
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Recipient : Accelagen
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : KIO-101
Therapeutic Area : Ophthalmology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : KIO-101, also known as PP-001, is a next-generation small molecule inhibitor of Dihydroorotate Dehydrogenase. It has demonstrated picomolar potency with a validated mechanism that may offer greater safety and tolerability than DHODH inhibitors currently ...
Brand Name : PP-001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 08, 2021
Lead Product(s) : KIO-101
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PP-001
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
EyeGate Pharma Completes Target Enrollment in Phase 2 Proof-of-Concept Study to Evaluate PP-001
Details : PP-001, an immune-modulating molecule, is an inhibitor of dihydroorotate dehydrogenase (“DHODH”) and is first-in-class for ophthalmology indications.
Brand Name : PP-001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 08, 2021
Lead Product(s) : PP-001
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PP-001
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $11.0 million
Deal Type : Public Offering
Details : PP-001, EyeGate’s lead clinical-stage drug product, is a next-generation, non-steroidal, immuno-modulatory and small-molecule inhibitor of Dihydroorotate Dehydrogenase.
Brand Name : PP-001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 11, 2021
Lead Product(s) : PP-001
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $11.0 million
Deal Type : Public Offering
Lead Product(s) : Hyaluronic Acid,Antibiotic
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
EyeGate Pharma Confirms Path Forward with FDA to Develop Combination Product
Details : FDA has granted Aquestive's AQST-108 Fast Track designation, an oral sublingual film formulation that delivers systemic epinephrine in development utilizing proprietary Aquestive PharmFilm ® technologies for treatment of allergic reactions, including an...
Brand Name : MoxiGel
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 12, 2020
Lead Product(s) : Hyaluronic Acid,Antibiotic
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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