[{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"JAPAN","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Rovatirelin","moa":"Thyrotropin releasing hormone receptor","graph1":"Neurology","graph2":"Phase III","graph3":"Kissei Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Kissei Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Kissei Pharmaceutical \/ Not Applicable"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"CG Oncology","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2020","type":"Licensing Agreement","leadProduct":"CG0070","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Kissei Pharmaceutical","amount2":0.14000000000000001,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.14000000000000001,"dosageForm":"","sponsorNew":"Kissei Pharmaceutical \/ Kissei Pharmaceutical","highestDevelopmentStatusID":"10","companyTruncated":"Kissei Pharmaceutical \/ Kissei Pharmaceutical"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"Affamed","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"JAPAN","productType":"Undisclosed","year":"2020","type":"Licensing Agreement","leadProduct":"KDT-3594","moa":"Dopamine receptor","graph1":"Neurology","graph2":"Phase II","graph3":"Kissei Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Kissei Pharmaceutical \/ Affamed","highestDevelopmentStatusID":"8","companyTruncated":"Kissei Pharmaceutical \/ Affamed"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"CG Oncology","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2020","type":"Series D Financing","leadProduct":"CG0070","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Kissei Pharmaceutical","amount2":0.050000000000000003,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0.050000000000000003,"dosageForm":"Intravesical Injection","sponsorNew":"Kissei Pharmaceutical \/ Kissei Pharmaceutical","highestDevelopmentStatusID":"10","companyTruncated":"Kissei Pharmaceutical \/ Kissei Pharmaceutical"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"EA Pharma","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"JAPAN","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Carotegrast Methyl","moa":"Alpha4 integrin","graph1":"Gastroenterology","graph2":"Phase III","graph3":"Kissei Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Kissei Pharmaceutical \/ EA Pharma","highestDevelopmentStatusID":"10","companyTruncated":"Kissei Pharmaceutical \/ EA Pharma"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"Amgen Inc","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Avacopan","moa":"C5a receptor","graph1":"Immunology","graph2":"Approved","graph3":"Kissei Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Kissei Pharmaceutical \/ Kissei Pharmaceutical","highestDevelopmentStatusID":"12","companyTruncated":"Kissei Pharmaceutical \/ Kissei Pharmaceutical"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"CG Oncology","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Large molecule","year":"2021","type":"Not Applicable","leadProduct":"CG0070","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Kissei Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Injection","sponsorNew":"Kissei Pharmaceutical \/ CG Oncology","highestDevelopmentStatusID":"10","companyTruncated":"Kissei Pharmaceutical \/ CG Oncology"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"Sanwa Kagaku Kenkyusho","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"JAPAN","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Upacicalcet Sodium","moa":"","graph1":"Endocrinology","graph2":"Approved","graph3":"Kissei Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kissei Pharmaceutical \/ Kissei Pharmaceutical","highestDevelopmentStatusID":"12","companyTruncated":"Kissei Pharmaceutical \/ Kissei Pharmaceutical"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"Rigel Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Fostamatinib Disodium Hexahydrate","moa":"SYK","graph1":"Immunology","graph2":"Approved","graph3":"Kissei Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Kissei Pharmaceutical \/ Kissei Pharmaceutical","highestDevelopmentStatusID":"12","companyTruncated":"Kissei Pharmaceutical \/ Kissei Pharmaceutical"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"Rigel Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Licensing Agreement","leadProduct":"Olutasidenib","moa":"","graph1":"Oncology","graph2":"Approved","graph3":"Kissei Pharmaceutical","amount2":0.16,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0.16,"dosageForm":"","sponsorNew":"Kissei Pharmaceutical \/ Kissei Pharmaceutical","highestDevelopmentStatusID":"12","companyTruncated":"Kissei Pharmaceutical \/ Kissei Pharmaceutical"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"Tai Tien Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"JAPAN","productType":"Other Small Molecule","year":"2025","type":"Licensing Agreement","leadProduct":"Fostamatinib Disodium Hexahydrate","moa":"Tyrosine-protein kinase 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Find Clinical Drug Pipeline Developments & Deals by Kissei Pharmaceutical

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                          Top Deals by Deal Size (USD bn)

                          01

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Under the licensing agreement, Tai Tien will gain the rights to develop and commercialize Tavalisse (fostamatinib disodium hexahydrate) in Taiwan.

                          Product Name : Tavalisse

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          January 07, 2025

                          Lead Product(s) : Fostamatinib Disodium Hexahydrate

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Sponsor : Tai Tien Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          02

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : The agreement aims to develop and commercialize Rezlidhia (olutasidenib) in all current and potential indications in Japan, the Republic of Korea and Taiwan.

                          Product Name : Rezlidhia

                          Product Type : Small molecule

                          Upfront Cash : $10.0 million

                          September 03, 2024

                          Lead Product(s) : Olutasidenib

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Recipient : Rigel Pharmaceuticals

                          Deal Size : $162.5 million

                          Deal Type : Licensing Agreement

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                          03

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : The Phase 3 clinical study (n=34) showed that patients receiving Tavalisse(Fostamatinib Disodium Hexahydrate) achieved a stable platelet response significantly higher than patients receiving a placebo control for the treatment of adult chronic immune thr...

                          Product Name : Tavalisse

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 21, 2021

                          Lead Product(s) : Fostamatinib Disodium Hexahydrate

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Recipient : Rigel Pharmaceuticals

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : UPASITA® is administered by intravenous injection to dialysis patients through dialysis circuit and it is possible to adjust the dose and control the medication under the control of physicians or medical staffs.

                          Product Name : Upasita

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 19, 2021

                          Lead Product(s) : Upacicalcet Sodium

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Approved

                          Recipient : Sanwa Kagaku Kenkyusho

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : CG0070, a oncolytic immunotherapy in which adenovirus is genetically modified to enhance bladder tumor cells selectivity and anticancer activity, and is injected into the bladder using a urinary tract catheter.

                          Product Name : CG0070

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 24, 2021

                          Lead Product(s) : CG0070

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : CG Oncology

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : If approved, avacopan would be the first-in-class orally administered selective complement 5a receptor inhibitor exerting an anti-inflammatory effect, for the treatment of patients with ANCA-associated vasculitis.

                          Product Name : CCX168

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 01, 2021

                          Lead Product(s) : Avacopan,Rituximab,Cyclophosphamide

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Recipient : Amgen Inc

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Primary endpoint was achieved in Phase III clinical study (AJM300/CT3) of AJM300 (nonproprietary name: carotegrast methyl), which EA Pharma and Kissei Pharmaceutical have developed for treatment of ulcerative colitis.

                          Product Name : AJM300

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 13, 2021

                          Lead Product(s) : Carotegrast Methyl

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase III

                          Sponsor : EA Pharma

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : The financing will support the advancement of CG Oncology’s late-stage clinical programs for its lead oncolytic immunotherapy, CG0070, including an ongoing global Phase 3 trial (BOND3) with CG0070 and a combination Phase 2 study of CG0070 with KEYTRUDA...

                          Product Name : CG0070

                          Product Type : Large molecule

                          Upfront Cash : Undisclosed

                          December 10, 2020

                          Lead Product(s) : CG0070

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Recipient : CG Oncology

                          Deal Size : $47.0 million

                          Deal Type : Series D Financing

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                          09

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : Under this agreement, Kissei grants Affamed the exclusive right for development and commercialization in China, Taiwan, Hong Kong, Macao and six Southeast Asian countries (Singapore, Malaysia, Thailand, Indonesia, Vietnam, and Philippines.

                          Product Name : KDT-3594

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          October 09, 2020

                          Lead Product(s) : KDT-3594

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Affamed

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          10

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : The licensing agreement will provide production and commercial prospects for the immunotherapy drug CG0070 from CG Oncology in Japan, South Korea, Taiwan and other Asian countries, except China.

                          Product Name : Undisclosed

                          Product Type : Large molecule

                          Upfront Cash : $10.0 million

                          March 26, 2020

                          Lead Product(s) : CG0070,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Recipient : CG Oncology

                          Deal Size : $140.0 million

                          Deal Type : Licensing Agreement

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