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    [{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"JAPAN","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Rovatirelin","moa":"Thyrotropin releasing hormone receptor","graph1":"Neurology","graph2":"Phase III","graph3":"Kissei Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Kissei Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Kissei Pharmaceutical \/ Not Applicable"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"CG Oncology","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2020","type":"Licensing Agreement","leadProduct":"CG0070","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Kissei 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Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Kissei Pharmaceutical \/ EA Pharma","highestDevelopmentStatusID":"10","companyTruncated":"Kissei Pharmaceutical \/ EA Pharma"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"Amgen Inc","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Avacopan","moa":"C5a receptor","graph1":"Immunology","graph2":"Approved","graph3":"Kissei Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Kissei Pharmaceutical \/ Kissei Pharmaceutical","highestDevelopmentStatusID":"12","companyTruncated":"Kissei Pharmaceutical \/ Kissei Pharmaceutical"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"CG Oncology","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Large molecule","year":"2021","type":"Not Applicable","leadProduct":"CG0070","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Kissei Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravesical Injection","sponsorNew":"Kissei Pharmaceutical \/ CG Oncology","highestDevelopmentStatusID":"10","companyTruncated":"Kissei Pharmaceutical \/ CG Oncology"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"Sanwa Kagaku Kenkyusho","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"JAPAN","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Upacicalcet Sodium","moa":"","graph1":"Endocrinology","graph2":"Approved","graph3":"Kissei Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Kissei Pharmaceutical \/ Kissei Pharmaceutical","highestDevelopmentStatusID":"12","companyTruncated":"Kissei Pharmaceutical \/ Kissei Pharmaceutical"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"Rigel Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Fostamatinib Disodium Hexahydrate","moa":"SYK","graph1":"Immunology","graph2":"Approved","graph3":"Kissei Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Kissei Pharmaceutical \/ Kissei Pharmaceutical","highestDevelopmentStatusID":"12","companyTruncated":"Kissei Pharmaceutical \/ Kissei Pharmaceutical"},{"orgOrder":0,"company":"Kissei Pharmaceutical","sponsor":"Rigel Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Licensing Agreement","leadProduct":"Olutasidenib","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Kissei Pharmaceutical","amount2":0.16,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Kissei Pharmaceutical \/ Kissei Pharmaceutical","highestDevelopmentStatusID":"12","companyTruncated":"Kissei Pharmaceutical \/ Kissei Pharmaceutical"}]

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                            01

                            Kissei Pharmaceutical

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                            Lead Product(s) : Olutasidenib

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Recipient : Rigel Pharmaceuticals

                            Deal Size : $162.5 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Rigel Expands REZLIDHIA® Partnership with Kissei for Japan, Korea, Taiwan

                            Details : The agreement aims to develop and commercialize Rezlidhia (olutasidenib) in all current and potential indications in Japan, the Republic of Korea and Taiwan.

                            Brand Name : Rezlidhia

                            Molecule Type : Small molecule

                            Upfront Cash : $10.0 million

                            September 03, 2024

                            Lead Product(s) : Olutasidenib

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Recipient : Rigel Pharmaceuticals

                            Deal Size : $162.5 million

                            Deal Type : Licensing Agreement

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                            02

                            Kissei Pharmaceutical

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                            Lead Product(s) : Fostamatinib Disodium Hexahydrate

                            Therapeutic Area : Immunology

                            Study Phase : Phase III

                            Recipient : Rigel Pharmaceuticals

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Fostamatinib Meets Primary Endpoint in Phase 3 Trial in Japan for Treatment of Chronic Immune Thrombocytopenia

                            Details : The Phase 3 clinical study (n=34) showed that patients receiving Tavalisse(Fostamatinib Disodium Hexahydrate) achieved a stable platelet response significantly higher than patients receiving a placebo control for the treatment of adult chronic immune thr...

                            Brand Name : Tavalisse

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 21, 2021

                            Lead Product(s) : Fostamatinib Disodium Hexahydrate

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase III

                            Recipient : Rigel Pharmaceuticals

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Kissei Pharmaceutical

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                            Lead Product(s) : Upacicalcet Sodium

                            Therapeutic Area : Endocrinology

                            Study Phase : Approved

                            Recipient : Sanwa Kagaku Kenkyusho

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Launch of UPASITA® IV Injection Syringe for the Treatment of Secondary Hyperparathyroidism in Dialysis Patien...

                            Details : UPASITA® is administered by intravenous injection to dialysis patients through dialysis circuit and it is possible to adjust the dose and control the medication under the control of physicians or medical staffs.

                            Brand Name : Upasita

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 19, 2021

                            Lead Product(s) : Upacicalcet Sodium

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Approved

                            Recipient : Sanwa Kagaku Kenkyusho

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Kissei Pharmaceutical

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                            Kissei Pharmaceutical

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                            Lead Product(s) : CG0070

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : CG Oncology

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Participation in Global Phase III Clinical Trial For CG0070, a Drug for Bladder Cancer

                            Details : CG0070, a oncolytic immunotherapy in which adenovirus is genetically modified to enhance bladder tumor cells selectivity and anticancer activity, and is injected into the bladder using a urinary tract catheter.

                            Brand Name : CG0070

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            March 24, 2021

                            Lead Product(s) : CG0070

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : CG Oncology

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Kissei Pharmaceutical

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                            Kissei Pharmaceutical

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                            Lead Product(s) : Avacopan,Rituximab,Cyclophosphamide

                            Therapeutic Area : Immunology

                            Study Phase : Phase III

                            Recipient : Amgen Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Kissei Pharmaceutical Reports Submission of New Drug Application for Avacopan (CCX168), a Complement C5a Recep...

                            Details : If approved, avacopan would be the first-in-class orally administered selective complement 5a receptor inhibitor exerting an anti-inflammatory effect, for the treatment of patients with ANCA-associated vasculitis.

                            Brand Name : CCX168

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 01, 2021

                            Lead Product(s) : Avacopan,Rituximab,Cyclophosphamide

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase III

                            Recipient : Amgen Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Kissei Pharmaceutical

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                            Lead Product(s) : Carotegrast Methyl

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase III

                            Sponsor : EA Pharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Results of Phase III Clinical Study of AJM300 for Treatment of Ulcerative Colitis Conducted in Japan (AJM300/C...

                            Details : Primary endpoint was achieved in Phase III clinical study (AJM300/CT3) of AJM300 (nonproprietary name: carotegrast methyl), which EA Pharma and Kissei Pharmaceutical have developed for treatment of ulcerative colitis.

                            Brand Name : AJM300

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 13, 2021

                            Lead Product(s) : Carotegrast Methyl

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase III

                            Sponsor : EA Pharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Kissei Pharmaceutical

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                            Lead Product(s) : CG0070

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Recipient : CG Oncology

                            Deal Size : $47.0 million

                            Deal Type : Series D Financing

                            DEALS_DEV arrow-down

                            CG Oncology Closes $47 Million Series D Financing

                            Details : The financing will support the advancement of CG Oncology’s late-stage clinical programs for its lead oncolytic immunotherapy, CG0070, including an ongoing global Phase 3 trial (BOND3) with CG0070 and a combination Phase 2 study of CG0070 with KEYTRUDA...

                            Brand Name : CG0070

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            December 10, 2020

                            Lead Product(s) : CG0070

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Recipient : CG Oncology

                            Deal Size : $47.0 million

                            Deal Type : Series D Financing

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                            08

                            Kissei Pharmaceutical

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                            Lead Product(s) : KDT-3594

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Affamed

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Licensing Agreement with Affamed for KDT-3594, a Novel Investigational Drug for Parkinson's Disease

                            Details : Under this agreement, Kissei grants Affamed the exclusive right for development and commercialization in China, Taiwan, Hong Kong, Macao and six Southeast Asian countries (Singapore, Malaysia, Thailand, Indonesia, Vietnam, and Philippines.

                            Brand Name : KDT-3594

                            Molecule Type : Undisclosed

                            Upfront Cash : Undisclosed

                            October 09, 2020

                            Lead Product(s) : KDT-3594

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Affamed

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            09

                            Kissei Pharmaceutical

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                            Kissei Pharmaceutical

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                            Lead Product(s) : CG0070,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Recipient : CG Oncology

                            Deal Size : $140.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            CG Oncology Announces License and Commercialization Agreement with Kissei Pharmaceutical

                            Details : The licensing agreement will provide production and commercial prospects for the immunotherapy drug CG0070 from CG Oncology in Japan, South Korea, Taiwan and other Asian countries, except China.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : $10.0 million

                            March 26, 2020

                            Lead Product(s) : CG0070,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Recipient : CG Oncology

                            Deal Size : $140.0 million

                            Deal Type : Licensing Agreement

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                            10

                            Kissei Pharmaceutical

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                            Lead Product(s) : Rovatirelin

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Kissei announces the publication of the results of phase III clinical trials of rovatirelin for the treatment ...

                            Details : In this paper, to review the results of both phase III clinical trials, a pooled (post hoc) analysis was performed with patients who met the inclusion criteria for the additional phase III trial

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 22, 2020

                            Lead Product(s) : Rovatirelin

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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