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Pharma","amount2":0.14000000000000001,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.14000000000000001,"dosageForm":"","sponsorNew":"Kite Pharma \/ Kite Pharma","highestDevelopmentStatusID":"4","companyTruncated":"Kite Pharma \/ Kite Pharma"},{"orgOrder":0,"company":"Kite Pharma","sponsor":"Daiichi Sankyo","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Licensing Agreement","leadProduct":"Axicabtagene Ciloleucel","moa":"","graph1":"Oncology","graph2":"Approved","graph3":"Kite Pharma","amount2":0.25,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Oncology","amount2New":0.25,"dosageForm":"Infusion","sponsorNew":"Kite Pharma \/ Daiichi Sankyo","highestDevelopmentStatusID":"12","companyTruncated":"Kite Pharma \/ Daiichi Sankyo"},{"orgOrder":0,"company":"Kite Pharma","sponsor":"Epic 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Pharma \/ Kite Pharma","highestDevelopmentStatusID":"6","companyTruncated":"Kite Pharma \/ Kite Pharma"},{"orgOrder":0,"company":"Kite Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Not Applicable","leadProduct":"Axicabtagene Ciloleucel","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Kite Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Kite Pharma \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Kite Pharma \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals by Kite Pharma

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Yescarta (axicabtagene ciloleucel) is a CD19-directed genetically modified autologous T cell immunotherapy indicated for the treatment of relapsed/refractory large b-cell lymphoma.

                          Brand Name : Yescarta

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 21, 2023

                          Lead Product(s) : Axicabtagene Ciloleucel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Under the expanded collaboration, Kite has exercised its option to negotiate a license for Arcellx's ARC-SparX program, ACLX-001, in multiple myeloma, which is comprised of ARC-T cells and SparX proteins that target BCMA.

                          Brand Name : ACLX-001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : $85.0 million

                          November 15, 2023

                          Lead Product(s) : ACLX-001

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Arcellx

                          Deal Size : $285.0 million

                          Deal Type : Expanded Collaboration

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Under the agreement, Kite will gain access to Epic Bio’s gene regulation platform to potentially develop next-generation cancer cell therapies and Epic Bio will develop constructs for Kite-selected targets for use in CAR T-cell therapies directed to bl...

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          October 31, 2023

                          Lead Product(s) : CAR T-cell Therapy

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Recipient : Epic Bio

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Under the agreement, Kite obtains marketing authorization in Japan for Yescarta® (axicabtagene ciloleucel), a CAR T-cell therapy, and is approved in Japan for the treatment of patients with relapsed or refractory large B-cell lymphomas, a type of non-Ho...

                          Brand Name : Yescarta

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : $50.0 million

                          June 22, 2023

                          Lead Product(s) : Axicabtagene Ciloleucel

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Daiichi Sankyo

                          Deal Size : $250.0 million

                          Deal Type : Licensing Agreement

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                          05

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The fundings will advance the development of Ensoma’s Engenious™ in vivo engineered cell therapy platform and pipeline of genomic medicines for immuno-oncology, genetic disease and other therapeutic applications.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          May 16, 2023

                          Lead Product(s) : Genomic Medicine

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Recipient : Ensoma

                          Deal Size : $135.0 million

                          Deal Type : Series B Financing

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                          06

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Yescarta ® (axicabtagene ciloleucel) is a CD19-directed genetically modified autologous T cell immunotherapy, binds to CD19-expressing cancer cells and normal B cells. It is indicated for treating relapsed/refractory large B-cell lymphoma.

                          Brand Name : Yescarta

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          March 21, 2023

                          Lead Product(s) : Axicabtagene Ciloleucel

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Tmunity Therapeutics is developing TmXX-01 for the development of B cell malignancies. The acquisition will provide Kite with pre-clinical and clinical programs, including an armored CAR T technology platform.

                          Brand Name : TmXX-01

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          February 22, 2023

                          Lead Product(s) : TmXX-01

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Kite Pharma

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          08

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : KTE-X19 (brexucabtagene autoleucel) is a modified autologous chimeric antigen receptor T cell therapy employing a modified murine anti-CD19 single-chain variable linked to CD28 and CD3ζ co-stimulatory domains for relapsed and refractory B-Cell acute lym...

                          Brand Name : Tecartus

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          February 09, 2023

                          Lead Product(s) : Brexucabtagene Autoleucel

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Kite and Arcellx were jointly working to advance and commercialize the CART-ddBCMA asset for relapsed or refractory multiple myeloma in U.S., and Kite was supposed to commercialize outside the U.S.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : $225.0 million

                          January 30, 2023

                          Lead Product(s) : CART-ddBCMA

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Recipient : Arcellx

                          Deal Size : $325.0 million

                          Deal Type : Termination

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                          10

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Yescarta (axicabtagene ciloleucel) is a CAR T-cell therapy directed against CD19 (a cell membrane protein), which harnesses a patient’s own immune system to fight cancer.

                          Brand Name : Yescarta

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 22, 2022

                          Lead Product(s) : Axicabtagene Ciloleucel

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Daiichi Sankyo

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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