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Tedromer","moa":"VEGF","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Kodiak Sciences \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Inapplicable"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2022","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGF","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Kodiak Sciences \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Inapplicable"},{"orgOrder":0,"company":"Kodiak Sciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2025","type":"Inapplicable","leadProduct":"Tarcocimab Tedromer","moa":"VEGF","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Kodiak Sciences","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Kodiak Sciences \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Kodiak Sciences \/ Inapplicable"}]

Find Clinical Drug Pipeline Developments & Deals by Kodiak Sciences

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01

Immuno-Oncology 360
Not Confirmed
Immuno-Oncology 360
Not Confirmed

Details : KSI-301 (tarcocimab tedromer) is designed to maintain potent and effective drug levels in ocular tissues for longer than existing anti-VEGF therapies. It is evaluated for diabetic retinopathy.

Product Name : KSI-301

Product Type : Antibody-drug Conjugate

Upfront Cash : Inapplicable

March 10, 2025

Lead Product(s) : Tarcocimab Tedromer

Therapeutic Area : Ophthalmology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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02

Immuno-Oncology 360
Not Confirmed
Immuno-Oncology 360
Not Confirmed

Details : The partnership aims to advance the discovery of novel multi-target antibodies to treat ophthalmic diseases, leveraging Nona's proprietary Harbour Mice fully human antibody platform.

Product Name : Undisclosed

Product Type : Large molecule

Upfront Cash : Undisclosed

December 09, 2024

Lead Product(s) : Undisclosed

Therapeutic Area : Ophthalmology

Highest Development Status : Discovery Platform

Recipient : Nona Biosciences

Deal Size : Undisclosed

Deal Type : Partnership

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03

Immuno-Oncology 360
Not Confirmed
Immuno-Oncology 360
Not Confirmed

Details : KSI-301 (tarcocimab tedromer) maintains potent drug levels in ocular tissues longer than existing anti-VEGF therapies, currently under investigation for neovascular age-related macular degeneration.

Product Name : KSI-301

Product Type : Antibody-drug Conjugate

Upfront Cash : Inapplicable

May 13, 2024

Lead Product(s) : Tarcocimab Tedromer

Therapeutic Area : Ophthalmology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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04

Immuno-Oncology 360
Not Confirmed
Immuno-Oncology 360
Not Confirmed

Details : KSI-301 (tarcocimab tedromer) is designed to maintain potent and effective drug levels in ocular tissues for longer than existing anti-VEGF therapies, which is investigated for the treatment of neovascular age-related macular degeneration and diabetic ma...

Product Name : KSI-301

Product Type : Antibody-drug Conjugate

Upfront Cash : Inapplicable

November 06, 2023

Lead Product(s) : Tarcocimab Tedromer

Therapeutic Area : Ophthalmology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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05

Immuno-Oncology 360
Not Confirmed
Immuno-Oncology 360
Not Confirmed

Details : KSI-301 (tarcocimab tedromer) is designed to maintain potent and effective drug levels in ocular tissues for longer than existing anti-VEGF therapies, which is investigated for the treatment of neovascular age-related macular degeneration and diabetic ma...

Product Name : KSI-301

Product Type : Antibody-drug Conjugate

Upfront Cash : Inapplicable

July 24, 2023

Lead Product(s) : Tarcocimab Tedromer

Therapeutic Area : Ophthalmology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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06

Immuno-Oncology 360
Not Confirmed
Immuno-Oncology 360
Not Confirmed

Details : KSI-501 is a bispecific ABC that is designed to inhibit two mechanisms implicated in vascular endothelial growth factor ("VEGF") and interleukin-6 (IL-6), a pro-inflammatory cytokine and growth factor implicated in the pathophysiology of multiple retinal...

Product Name : KSI-501

Product Type : Large molecule

Upfront Cash : Not Applicable

April 03, 2023

Lead Product(s) : KSI-501

Therapeutic Area : Ophthalmology

Highest Development Status : Phase I

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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07

Immuno-Oncology 360
Not Confirmed
Immuno-Oncology 360
Not Confirmed

Details : KSI-301 (tarcocimab tedromer) is an investigational anti-VEGF therapy built on Kodiak's Antibody Biopolymer Conjugate (ABC) Platform and is designed to maintain potent and effective drug levels in ocular tissues for longer than existing available agents.

Product Name : KSI-301

Product Type : Antibody-drug Conjugate

Upfront Cash : Inapplicable

August 18, 2022

Lead Product(s) : Tarcocimab Tedromer

Therapeutic Area : Ophthalmology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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08

Immuno-Oncology 360
Not Confirmed
Immuno-Oncology 360
Not Confirmed

Details : Tarcocimab tedromer (KSI-301) dosed every two months met the primary endpoint of non-inferior visual acuity gains compared to aflibercept dosed every month, in patients with macular edema due to retinal vein occlusion.

Product Name : KSI-301

Product Type : Antibody-drug Conjugate

Upfront Cash : Inapplicable

August 08, 2022

Lead Product(s) : Tarcocimab Tedromer

Therapeutic Area : Ophthalmology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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09

Immuno-Oncology 360
Not Confirmed
Immuno-Oncology 360
Not Confirmed

Details : KSI-301 is an investigational anti-VEGF therapy built on Kodiak's Antibody Biopolymer Conjugate (ABC) Platform and is designed to maintain potent and effective drug levels in ocular tissues for longer than existing available agents.

Product Name : KSI-301

Product Type : Large molecule

Upfront Cash : Not Applicable

May 19, 2022

Lead Product(s) : KSI-301

Therapeutic Area : Ophthalmology

Highest Development Status : Phase III

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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10

Immuno-Oncology 360
Not Confirmed
Immuno-Oncology 360
Not Confirmed

Details : KSI-301 is an investigational anti-VEGF therapy built on Kodiak's Antibody Biopolymer Conjugate (ABC) Platform and is designed to maintain potent and effective drug levels in ocular tissues for longer than existing available agents.

Product Name : KSI-301

Product Type : Large molecule

Upfront Cash : Not Applicable

April 29, 2022

Lead Product(s) : KSI-301

Therapeutic Area : Ophthalmology

Highest Development Status : Phase III

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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