Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : RNA-based Therapy
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Discovery Platform
Sponsor : Novo Nordisk
Deal Size : $530.0 million
Deal Type : Collaboration
Korro Bio Announces Collaboration with Novo Nordisk to Develop Two Therapeutic Candidates
Details : The collaboration brings together Novo's deep cardiometabolic disease understanding and drug development experience with Korro’s platform to develop RNA editing product candidates.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 16, 2024
Lead Product(s) : RNA-based Therapy
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Discovery Platform
Sponsor : Novo Nordisk
Deal Size : $530.0 million
Deal Type : Collaboration
Lead Product(s) : KRRO-110
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Deep Track Capital
Deal Size : $70.0 million
Deal Type : Private Placement
Korro Announces $70 Million Private Placement
Details : The net proceeds will be used to support the clinical advancement of Korro's lead product KRRO-110 for treating patients suffering from alpha-1 antitrypsin deficiency.
Brand Name : KRRO-110
Molecule Type : Large molecule
Upfront Cash : Undisclosed
April 18, 2024
Lead Product(s) : KRRO-110
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Deep Track Capital
Deal Size : $70.0 million
Deal Type : Private Placement
Lead Product(s) : KRRO-110
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Korro Highlights Data for AAT and RNA Editing Program Progress
Details : KRRO-110 is based on Korro’s proprietary RNA editing platform, OPERA™. It is being evaluated in preclinical studies for the treatment of Alpha-1 Antitrypsin Deficiency.
Brand Name : KRRO-110
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 18, 2024
Lead Product(s) : KRRO-110
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : KRRO-110
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : KRRO-110 is an oligonucleotide restorator, which works by targeting A1AT protein, it is being investigated for the treatment of Alpha-1 Antitrypsin Deficiency.
Brand Name : KRRO-110
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 07, 2023
Lead Product(s) : KRRO-110
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Study Phase : Discovery Platform
Recipient : Frequency Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Details : The combined company will focus on the advancement of Korro Bio’s portfolio of RNA editing programs including, OPERA platform which harnesses the body’s natural base editing system, specifically ADAR, to make targeted edits to a single RNA base.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
November 03, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery Platform
Recipient : Frequency Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Study Phase : Discovery Platform
Recipient : Frequency Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Korro Bio and Frequency Therapeutics Announce Merger Agreement
Details : The combined company will focus on the advancement of Korro Bio’s portfolio of RNA editing programs including, OPERA platform which harnesses the body’s natural base editing system, specifically ADAR, to make targeted edits to a single RNA base.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
July 14, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery Platform
Recipient : Frequency Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : RNA-based Therapeutic
Therapeutic Area : Genetic Disease
Study Phase : Undisclosed
Sponsor : Genevant Sciences
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The Collaboration to combine Korro’s RNA editing technology with Genevant’s industry-leading LNP technology to develop a differentiated therapeutic option for patients with Alpha-1 Antitrypsin Deficiency (AATD).
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 07, 2023
Lead Product(s) : RNA-based Therapeutic
Therapeutic Area : Genetic Disease
Highest Development Status : Undisclosed
Sponsor : Genevant Sciences
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Genetic Medicine
Therapeutic Area : Genetic Disease
Study Phase : Discovery
Sponsor : Eventide Asset Management
Deal Size : $116.0 million
Deal Type : Series B Financing
Details : The financing will enable Korro to advance its lead program in development for patients with Alpha-1 Antitrypsin Deficiency (AATD), an inherited genetic disorder leading to liver and lung disease with RNA editing platform.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 05, 2022
Lead Product(s) : Genetic Medicine
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery
Sponsor : Eventide Asset Management
Deal Size : $116.0 million
Deal Type : Series B Financing
Lead Product(s) : RNA editing therapies
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Wu Capital
Deal Size : $91.5 million
Deal Type : Series A Financing
Korro Bio Closes $91.5 Million Series A Financing to Advance the Next Frontier in RNA Therapeutics
Details : This financing enables Korro to advance its lead program to IND filing and establish a broad portfolio of innovative RNA editing therapies. Korro’s OPERA platform, harnesses the body’s natural base editing system, specifically ADAR to make targeted e...
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
September 10, 2020
Lead Product(s) : RNA editing therapies
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Wu Capital
Deal Size : $91.5 million
Deal Type : Series A Financing
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