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    [{"orgOrder":0,"company":"Kymera Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"KT-474","moa":"IRAK4","graph1":"Immunology","graph2":"Preclinical","graph3":"Kymera Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Kymera Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Kymera Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Kymera Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"KT-474","moa":"IRAK4","graph1":"Dermatology","graph2":"Phase II","graph3":"Kymera Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph 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II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Kymera Therapeutics \/ Sanofi","highestDevelopmentStatusID":"8","companyTruncated":"Kymera Therapeutics \/ Sanofi"}]

    Find Clinical Drug Pipeline Developments & Deals for KT-474

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    KT-474

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                            01

                            Kymera Therapeutics

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                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Morgan Stanley

                            Deal Size : $275.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Kymera Therapeutics Announces Closing Of Upsized $275 Million Public Offering

                            Details : The net proceeds will advance the preclinical and clinical degrader programs, including SAR444656 (KT-474) for treating immune-inflammatory diseases like hidradenitis suppurativa & atopic dermatitis.

                            Product Name : KT-474

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            September 01, 2024

                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Morgan Stanley

                            Deal Size : $275.0 million

                            Deal Type : Public Offering

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                            02

                            Kymera Therapeutics

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                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Morgan Stanley

                            Deal Size : $258.7 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Kymera Therapeutics Announces Closing of Upsized $225 Million Public Offering

                            Details : Phathom intends to use the net proceeds from the offering to fund commercialization expenses and further clinical development of Voquezna (vonoprazan) for the treatment of Erosive GERD.

                            Product Name : KT-474

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            August 21, 2024

                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Morgan Stanley

                            Deal Size : $258.7 million

                            Deal Type : Public Offering

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                            03

                            Kymera Therapeutics

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                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Morgan Stanley

                            Deal Size : $225.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Kymera Therapeutics Announces Pricing of $225 Million Public Offering

                            Details : Kymera intends to use the net proceeds from the offering to continue advancing its pipeline, which includes SAR444656 (KT-474) being evaluated in the mid-stage for treating atopic dermatitis.

                            Product Name : KT-474

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            August 19, 2024

                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Morgan Stanley

                            Deal Size : $225.0 million

                            Deal Type : Public Offering

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                            04

                            Kymera Therapeutics

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                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Kymera Expands KT-474 (SAR444656) HS and AD Phase 2 Studies After Safety Review

                            Details : SAR444656 (KT-474), a first-in-class IRAK4 degrader, being developed for the treatment of immune-inflammatory diseases, such as hidradenitis suppurativa, atopic dermatitis.

                            Product Name : KT-474

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 07, 2024

                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Kymera Therapeutics

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                            Kymera Therapeutics

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                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Morgan Stanley

                            Deal Size : $275.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Kymera Therapeutics Announces Pricing of $275 Million Public Offering

                            Details : Kymera will use proceeds to advance its degrader programs, including SAR444656, a first-in-class IRAK4 degrader, for treating hidradenitis suppurativa and atopic dermatitis.

                            Product Name : KT-474

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            May 01, 2024

                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Morgan Stanley

                            Deal Size : $275.0 million

                            Deal Type : Public Offering

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                            06

                            Kymera Therapeutics

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                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Morgan Stanley

                            Deal Size : $287.5 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Kymera Therapeutics Announces Proposed Public Offering

                            Details : Kymera will use proceeds to advance its degrader programs, including SAR444656, a first-in-class IRAK4 degrader, for treating hidradenitis suppurativa and atopic dermatitis.

                            Product Name : KT-474

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            April 01, 2024

                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Morgan Stanley

                            Deal Size : $287.5 million

                            Deal Type : Public Offering

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                            07

                            Kymera Therapeutics

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                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Sanofi

                            Deal Size : $2,150.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Kymera Therapeutics Announces First Patient Dosed in Phase 2 Hidradenitis Suppurativa Clinical Trial of KT-474...

                            Details : Under the collaboration, Kymera is evaluating KT-474 (SAR444656), a first-in-class, investigational IRAK4 degrader, in the randomized Phase 2 clinical trial in hidradenitis suppurativa.

                            Product Name : KT-474

                            Product Type : Other Small Molecule

                            Upfront Cash : $150.0 million

                            October 27, 2023

                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Sanofi

                            Deal Size : $2,150.0 million

                            Deal Type : Collaboration

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                            08

                            Kymera Therapeutics

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                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Study Phase : Phase II

                            Sponsor : Sanofi

                            Deal Size : $2,150.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Kymera Therapeutics Announces First Patient Dosed in Phase 2 Atopic Dermatitis Clinical Trial of KT-474 (SAR44...

                            Details : Under the collaboration, Kymera is evaluating KT-474 (SAR444656), a first-in-class, investigational IRAK4 degrader, in the randomized Phase 2 clinical trial for Atopic Dermatitis.

                            Product Name : KT-474

                            Product Type : Other Small Molecule

                            Upfront Cash : $150.0 million

                            July 12, 2023

                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase II

                            Sponsor : Sanofi

                            Deal Size : $2,150.0 million

                            Deal Type : Collaboration

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                            09

                            Kymera Therapeutics

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                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I

                            Sponsor : Sanofi

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Kymera Announces Positive Results from Phase 1 Clinical Trial Evaluating KT-474 in Patients with HS and AD and...

                            Details : In patients with HS and AD, KT-474 demonstrated plasma PK in Part C that was comparable to healthy volunteers in MAD3. Initial Phase 2 clinical trial of KT-474 will investigate its potential in HS and AD with the first study initiating in 2023.

                            Product Name : KT-474

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 14, 2022

                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I

                            Sponsor : Sanofi

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Kymera Therapeutics

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                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Kymera Therapeutics Announces Key 2022 Goals and Milestones to Support Its Evolution into a Fully Integrated D...

                            Details : KT-474 completes dose escalation in healthy volunteer portion of Phase 1 trial, plans patient cohort and proof of biology data in 2022 for treatment of life-threatening diseases such as HS, AD, lymphomas and leukemias.

                            Product Name : KT-474

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 01, 2022

                            Lead Product(s) : KT-474

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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