[{"orgOrder":0,"company":"Kymera Therapeutics","sponsor":"Biotechnology Value Fund","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"UNITED KINGDOM","productType":"Small molecule","year":"2020","type":"Series C Financing","leadProduct":"Undisclosed","moa":"IRAK4","graph1":"Immunology","graph2":"Preclinical","graph3":"Kymera Therapeutics","amount2":0.10000000000000001,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Kymera Therapeutics \/ Biotechnology Value Fund","highestDevelopmentStatusID":"4","companyTruncated":"Kymera Therapeutics \/ Biotechnology Value Fund"},{"orgOrder":0,"company":"Kymera Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"","productType":"Undisclosed","year":"2020","type":"Not 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Find Clinical Drug Pipeline Developments & Deals by Kymera Therapeutics

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                          Top Deals by Deal Size (USD bn)

                          01

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : KT-621 is an investigational first-in-class once daily, oral STAT6 degrader. Currently;y, it is being evaluated for treating Atopic Dermatitis and Asthma.

                          Brand Name : KT-621

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 09, 2024

                          Lead Product(s) : KT-621

                          Therapeutic Area : Dermatology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Phathom intends to use the net proceeds from the offering to fund commercialization expenses and further clinical development of Voquezna (vonoprazan) for the treatment of Erosive GERD.

                          Brand Name : SAR444656

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          August 21, 2024

                          Lead Product(s) : KT-474

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Morgan Stanley

                          Deal Size : $258.7 million

                          Deal Type : Public Offering

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                          03

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Kymera intends to use the net proceeds from the offering to continue advancing its pipeline, which includes SAR444656 (KT-474) being evaluated in the mid-stage for treating atopic dermatitis.

                          Brand Name : SAR444656

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          August 19, 2024

                          Lead Product(s) : KT-474

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Morgan Stanley

                          Deal Size : $225.0 million

                          Deal Type : Public Offering

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                          04

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : SAR444656 (KT-474), a first-in-class IRAK4 degrader, being developed for the treatment of immune-inflammatory diseases, such as hidradenitis suppurativa, atopic dermatitis.

                          Brand Name : SAR444656

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 08, 2024

                          Lead Product(s) : KT-474

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Under the agreement, NEOsphere will utilize its target & E3-agnostic platform to screen molecular glue compounds on a proteome-wide level, to support Kymera’s robust drug discovery engine.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          May 14, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Recipient : NEOsphere Biotechnologies

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          06

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : KT-621 is a once daily, oral STAT6 degrader with a potential biologics-like efficacy profile, to address multiple diseases including atopic dermatitis, asthma and COPD.

                          Brand Name : KT-621

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 08, 2024

                          Lead Product(s) : KT-621

                          Therapeutic Area : Dermatology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The net proceeds will advance the preclinical and clinical degrader programs, including SAR444656 (KT-474) for treating immune-inflammatory diseases like hidradenitis suppurativa & atopic dermatitis.

                          Brand Name : SAR444656

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          January 09, 2024

                          Lead Product(s) : KT-474

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Morgan Stanley

                          Deal Size : $275.0 million

                          Deal Type : Public Offering

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                          08

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Kymera will use proceeds to advance its degrader programs, including SAR444656, a first-in-class IRAK4 degrader, for treating hidradenitis suppurativa and atopic dermatitis.

                          Brand Name : SAR444656

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          January 05, 2024

                          Lead Product(s) : KT-474

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Morgan Stanley

                          Deal Size : $275.0 million

                          Deal Type : Public Offering

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                          09

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Kymera will use proceeds to advance its degrader programs, including SAR444656, a first-in-class IRAK4 degrader, for treating hidradenitis suppurativa and atopic dermatitis.

                          Brand Name : SAR444656

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          January 04, 2024

                          Lead Product(s) : KT-474

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Morgan Stanley

                          Deal Size : $287.5 million

                          Deal Type : Public Offering

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                          10

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Under the collaboration, Kymera is evaluating KT-474 (SAR444656), a first-in-class, investigational IRAK4 degrader, in the randomized Phase 2 clinical trial for Atopic Dermatitis.

                          Brand Name : KT-474

                          Molecule Type : Small molecule

                          Upfront Cash : $150.0 million

                          December 07, 2023

                          Lead Product(s) : KT-474

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Sanofi

                          Deal Size : $2,150.0 million

                          Deal Type : Collaboration

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