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    [{"orgOrder":0,"company":"Kyverna Therapeutics","sponsor":"Vida Ventures","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Series A Financing","leadProduct":"T cells therapy","moa":"","graph1":"Immunology","graph2":"Undisclosed","graph3":"Kyverna Therapeutics","amount2":0.029999999999999999,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Immunology","amount2New":0.029999999999999999,"dosageForm":"","sponsorNew":"Kyverna Therapeutics \/ Vida Ventures","highestDevelopmentStatusID":"1","companyTruncated":"Kyverna Therapeutics \/ Vida Ventures"},{"orgOrder":0,"company":"Kyverna Therapeutics","sponsor":"Gilead Sciences","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Collaboration","leadProduct":"T cells therapy","moa":"","graph1":"Immunology","graph2":"Undisclosed","graph3":"Kyverna 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    Find Clinical Drug Pipeline Developments & Deals by Kyverna Therapeutics

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                            01

                            Kyverna Therapeutics

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                            Lead Product(s) : KYV-101

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Kyverna's KYV-101 Receives IND Clearance for Stiff-Person Syndrome Phase 2 Trial

                            Details : KYV-101 is an autologous, fully human CD19 CAR T-cell product candidate. It is being evaluated for the treatment of treatment-refractory stiff-person syndrome.

                            Brand Name : KYV-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            June 20, 2024

                            Lead Product(s) : KYV-101

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Kyverna Therapeutics

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                            Kyverna Therapeutics

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                            Lead Product(s) : KYV-101,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : $366.9 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Kyverna Therapeutics Closes IPO and Full Exercise of Underwriters' Purchase Option

                            Details : The net proceeds will be used for the development of KYV-101 for the patients suffering from autoimmune diseases such as multiple sclerosis and myasthenia gravis.

                            Brand Name : KYV-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            February 12, 2024

                            Lead Product(s) : KYV-101,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : $366.9 million

                            Deal Type : Public Offering

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                            03

                            Kyverna Therapeutics

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                            Kyverna Therapeutics

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                            Lead Product(s) : KYV-101,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : $319.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Kyverna Therapeutics Announces Pricing of Upsized Initial Public Offering

                            Details : The net proceeds will be used for the development of KYV-101 for the patients suffering from autoimmune diseases such as multiple sclerosis and myasthenia gravis.

                            Brand Name : KYV-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            February 07, 2024

                            Lead Product(s) : KYV-101,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : $319.0 million

                            Deal Type : Public Offering

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                            04

                            Kyverna Therapeutics

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                            Cosmoprof
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                            Kyverna Therapeutics

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                            Lead Product(s) : KYV-101

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Kyverna Accelerates into Another FDA Fast Track

                            Details : KYV-101 is an autologous, fully human CD19 CAR T-cell product candidate. It is under phase 1 clinical development for the treatment of Multiple Sclerosis.

                            Brand Name : KYV-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            January 19, 2024

                            Lead Product(s) : KYV-101

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Kyverna Therapeutics

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                            Cosmoprof
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                            Kyverna Therapeutics

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                            Lead Product(s) : KYV-101

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Kyverna's KYV-101 Receives FDA Clearance for Refractory Multiple Sclerosis

                            Details : KYV-101 is an autologous human CD19 CAR T-cell therapy in phase 1 trials for refractory progressive multiple sclerosis, targeting B cell-driven autoimmune diseases.

                            Brand Name : KYV-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            January 03, 2024

                            Lead Product(s) : KYV-101

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Kyverna Therapeutics

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                            Kyverna Therapeutics

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                            Lead Product(s) : KYV-101

                            Therapeutic Area : Immunology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Kyverna Therapeutics Granted FDA Fast Track Designation for KYV-101 in the Treatment of Patients With Refracto...

                            Details : KYV-101 is an autologous, fully human CD19 CAR T-cell product candidate for use in B cell-driven autoimmune diseases. It is being evaluated for the treatment of patients with refractory myasthenia gravis.

                            Brand Name : KYV-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            December 13, 2023

                            Lead Product(s) : KYV-101

                            Therapeutic Area : Immunology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Kyverna Therapeutics

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                            Cosmoprof
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                            Kyverna Therapeutics

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                            Cosmoprof
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                            Lead Product(s) : KYV-101

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Kyverna Therapeutics Announces FDA Clearance of Phase 2 IND for KYV-101, a Fully Human CD19 CAR T-Cell Therapy...

                            Details : KYV-101 is a novel, fully human anti-CD19 CAR T-cell therapy for use in B cell-driven autoimmune diseases such as Myasthenia Gravis and represents an innovative approach to fighting autoimmune diseases by harnessing the power of the body's immune system.

                            Brand Name : KYV-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            November 13, 2023

                            Lead Product(s) : KYV-101

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Kyverna Therapeutics

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                            Cosmoprof
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                            Kyverna Therapeutics

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                            Lead Product(s) : KYV-101

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Recipient : Oxford Biomedica

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Kyverna Therapeutics and Oxford Biomedica Sign License and Supply Agreement for LentiVector® Platform

                            Details : Under the agreement, Kyverna gains access to LentiVector® platform, the first commercially approved lentiviral-based gene delivery system, to use with any Kyverna product, including its anti-CD19 CAR T-cell therapies, KYV-101 and KYV-201 which specifica...

                            Brand Name : KYV-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 20, 2023

                            Lead Product(s) : KYV-101

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Recipient : Oxford Biomedica

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            09

                            Kyverna Therapeutics

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                            Cosmoprof
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                            Kyverna Therapeutics

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                            Lead Product(s) : KYV-101

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Kyverna Therapeutics Announces Achievement of 28-Day Post-Infusion Milestone for First U.S. Patient Dosed in P...

                            Details : KYV-101 is a novel, fully human anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for use in B cell-driven autoimmune diseases such as LN and represents an innovative approach to fighting autoimmune diseases by harnessing the power of the body's i...

                            Brand Name : KYV-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            September 13, 2023

                            Lead Product(s) : KYV-101

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Kyverna Therapeutics

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                            Cosmoprof
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                            Kyverna Therapeutics

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                            Lead Product(s) : KYV-101

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Bain Capital Life Sciences

                            Deal Size : $145.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Kyverna Therapeutics Extends Series B Financing Round to $145 Million and Brings in New Investors

                            Details : The net proceeds will support clinical development of novel fully human CAR T-cell therapies, KYV-101 and KYV-201, specifically target CD19, a protein expressed on the surface of B cells which is involved in various types of autoimmune diseases including...

                            Brand Name : KYV-101

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            August 03, 2023

                            Lead Product(s) : KYV-101

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Bain Capital Life Sciences

                            Deal Size : $145.0 million

                            Deal Type : Series B Financing

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