18
ALL1
Alembic Pharmaceuticals Limited1
Biocon1
Exemed Pharmaceuticals1
Glenmark Pharmaceuticals2
Lupin Ltd9
Novartis Pharmaceuticals Corporation1
Prague Scientific1
USV Private Limited1
Zydus LifesciencesYear
18
ALL1
20257
20243
20231
20224
20212
2020DEALS // DEV.
18
ALL2
Deals16
DevelopmentsCountry
18
ALL1
CZECH REPUBLIC8
INDIA9
SWITZERLAND18
ALL1
Dr. Reddy's Laboratories1
Inapplicable13
Not Applicable1
Otsuka Chemical Co Ltd2
Otsuka PharmaceuticalTherapeutic Area
18
ALL18
Cardiology/Vascular DiseasesStudy Phase
18
ALL1
Approved FDF15
Approved1
Phase III1
Phase IIDeal Type
3
ALL2
Agreement1
InapplicableProduct Type
18
ALL1
Other Small Molecule17
Small moleculeDosage Form
12
ALL2
Film-Coated Tablet3
Film-coated Tablet1
Film-coated tablet1
Oral Tablet, Film Coated3
Tablet2
Tablet, Film CoatedLead Product
18
ALL18
Sacubitril SodiumTarget
7
ALL7
NeprilysinLead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lupin Receives U.S. FDA Approval for Sacubitril and Valsartan Tablets
Details : Entresto-Generic (sacubitril and valsartan) is an oral angiotensin receptor neprilysin inhibitor, which is approved for the treatment of chronic heart failure.
Product Name : Entresto-Generic
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 24, 2025
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
USV Introduces OnArni, FDC of Sacubitril, Valsartan, For HF Management
Details : OnArni (sacubitril and valsartan) is an oral angiotensin receptor neprilysin inhibitor, which is approved for the treatment of chronic heart failure in 2 years and older patients.
Product Name : OnArni
Product Type : Small molecule
Upfront Cash : Not Applicable
October 15, 2024
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Exemed Receives CDSCO Nod For Study of Sacubitril Plus Valsartan Sustained-Release Tablet
Details : Sacubright (sacubitril and valsartan) is an oral angiotensin receptor neprilysin inhibitor, which is approved for the treatment of chronic heart failure in 2 years and older patients.
Product Name : Sacubright
Product Type : Small molecule
Upfront Cash : Not Applicable
October 04, 2024
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Biocon Unit Gets USFDA Nod For Generic Drug
Details : Sacubitril and valsartan is an oral angiotensin receptor neprilysin inhibitor, which is approved for the treatment of chronic heart failure in 2 years and older patients.
Product Name : Entresto-Generic
Product Type : Small molecule
Upfront Cash : Not Applicable
September 02, 2024
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Zydus Lifesciences gets USFDA nod to market chronic heart failure treatment drug
Details : Enresto-Generic (sacubitril and valsartan) is an oral neprilysin inhibitor, is approved for the treatment of additional indication of adults chronic heart failure.
Product Name : Entresto-Generic
Product Type : Small molecule
Upfront Cash : Not Applicable
July 10, 2024
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Alembic Pharmaceuticals receives USFDA final approval for Sacubitril and Valsartan Tablets
Details : A eneric formulation of sacubitril and valsartan, an oral neprilysin inhibitor, is approved for the treatment of additional indication of adults chronic heart failure.
Product Name : Entresto-Generic
Product Type : Small molecule
Upfront Cash : Not Applicable
May 29, 2024
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved
Sponsor : Otsuka Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Novartis Gets Japan Approval for Entresto Granular Tablets for Pediatric Heart Failure Use
Details : Entresto (sacubitril and valsartan) is an oral angiotensin receptor neprilysin inhibitor, which is approved for the treatment of additional indication of pediatric chronic heart failure.
Product Name : Entresto
Product Type : Small molecule
Upfront Cash : Not Applicable
March 26, 2024
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved
Sponsor : Otsuka Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved
Sponsor : Otsuka Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Novartis Gains Approval for Entresto for Pediatric Chronic Heart Failure
Details : Entresto (sacubitril and valsartan) is an oral angiotensin receptor neprilysin inhibitor, which is approved for the treatment of additional indication of pediatric chronic heart failure.
Product Name : Entresto
Product Type : Small molecule
Upfront Cash : Not Applicable
February 09, 2024
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved
Sponsor : Otsuka Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Novartis Entresto Receives Positive CHMP Opinion for Pediatric Heart Failure
Details : Entresto contains a neprilysin inhibitor, sacubitril, and an angiotensin receptor blocker, valsartan. It inhibits neprilysin via LBQ657, the active metabolite of the prodrug sacubitril, and blocks the angiotensin II type-1 receptor via valsartan in pedia...
Product Name : Entresto
Product Type : Small molecule
Upfront Cash : Not Applicable
March 31, 2023
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lupin Launches Sacubitril and Valsartan Combination Drug for Heart Failure Patients
Details : Sacubitril and Valsartan drug inhibits neprilysin and blocks angiotensin II type-I receptor, increasing the levels of peptides degraded by neprilysin. It is indicated to reduce the risk of cardiovascular death and hospitalization for heart failure.
Product Name : Valentas
Product Type : Small molecule
Upfront Cash : Not Applicable
January 18, 2023
Lead Product(s) : Sacubitril Sodium,Valsartan
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable