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    [{"orgOrder":0,"company":"Labcorp Drug Development","sponsor":"KBP Biosciences","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"KBP-5074","moa":"Mineralocorticoid receptor","graph1":"Nephrology","graph2":"Phase II","graph3":"Labcorp Drug Development","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Labcorp Drug Development \/ Labcorp Drug Development","highestDevelopmentStatusID":"8","companyTruncated":"Labcorp Drug Development \/ Labcorp Drug Development"},{"orgOrder":0,"company":"Labcorp Drug Development","sponsor":"KBP Biosciences","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"KBP-5074","moa":"Mineralocorticoid receptor","graph1":"Nephrology","graph2":"Phase 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Drug Development","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Labcorp Drug Development \/ Covance","highestDevelopmentStatusID":"6","companyTruncated":"Labcorp Drug Development \/ Covance"},{"orgOrder":0,"company":"Labcorp Drug Development","sponsor":"HiberCell","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"HC-5404","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Labcorp Drug Development","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Labcorp Drug Development \/ Covance","highestDevelopmentStatusID":"6","companyTruncated":"Labcorp Drug Development \/ Covance"},{"orgOrder":0,"company":"Labcorp Drug Development","sponsor":"HiberCell","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"HC-7366-K","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Labcorp Drug Development","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Immediate Releasse Capsule","sponsorNew":"Labcorp Drug Development \/ Covance","highestDevelopmentStatusID":"6","companyTruncated":"Labcorp Drug Development \/ Covance"},{"orgOrder":0,"company":"Labcorp Drug Development","sponsor":"Enterome","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Vaccine","year":"2022","type":"Not Applicable","leadProduct":"Bevacizumab","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Labcorp Drug Development","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Labcorp Drug Development \/ Covance, Inc","highestDevelopmentStatusID":"7","companyTruncated":"Labcorp Drug Development \/ Covance, Inc"}]

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                            01

                            Labcorp Drug Development

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                            Lead Product(s) : EO2401,Nivolumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Enterome

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Enterome Completes Patient Enrollment Of Phase 2 ROSALIE Study Evaluating Its Lead Immunotherapy, EO2401, In R...

                            Details : EO2401, in combination with an immune checkpoint inhibitor (nivolumab) +/- an anti-VEGF therapy (bevacizumab) in patients with first progression/recurrence of glioblastoma, an aggressive form of brain cancer.

                            Brand Name : EO2401

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            December 12, 2022

                            Lead Product(s) : EO2401,Nivolumab,Bevacizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Enterome

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Labcorp Drug Development

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                            Lead Product(s) : HC-7366-K

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : HiberCell

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            HiberCell Initiates its Phase 1a/b Clinical Trial of HC-7366 in Patients with Advanced Solid Tumors

                            Details : The first-in-human Phase 1a/b clinical trial, designed to establish maximum tolerated dose, while evaluating safety and tolerability, and to establish recommended Phase 2 dose for HC-7366, selective, orally bioavailable modulator of GNC2 in patients with...

                            Brand Name : HC-7366

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 24, 2022

                            Lead Product(s) : HC-7366-K

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : HiberCell

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : HC-5404

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : HiberCell

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            HiberCell Initiates Phase 1a Clinical Trial of HC-5404-FU, an ER Stress Modulator

                            Details : The primary endpoints are to establish HC-5404-FU’s Maximum Tolerated Dose (MTD) and to monitor its safety and tolerability in patients with selected, advanced solid tumors.

                            Brand Name : HC-5404-FU

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 10, 2021

                            Lead Product(s) : HC-5404

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : HiberCell

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Labcorp Drug Development

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                            Lead Product(s) : WM-S1-030

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Wellmarker Bio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            WellmarkerBio Receives Approval for Phase I Clinical Trial from the Australian Therapeutic Goods Administratio...

                            Details : Wellmarker has received approval from the Australian Therapeutic Goods Administration (TGA) for a Phase I clinical trial using WM-S1-030, a targeted anti-cancer drug for colorectal cancer and progressive cancer.

                            Brand Name : WM-S1-030

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 03, 2021

                            Lead Product(s) : WM-S1-030

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Wellmarker Bio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Labcorp Drug Development

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                            Lead Product(s) : KBP-5074

                            Therapeutic Area : Nephrology

                            Study Phase : Phase II

                            Recipient : KBP Biosciences

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            KBP Biosciences Announces Data Presentation at the American Society of Nephrology Annual Meeting

                            Details : The upcoming data to be presented at the American Society of Nephrology (ASN) Annual Meeting showcases a pre-clinical study investigating the effect of KBP-5074 on aldosterone-mediated renal injury in the uninephrectomized SD rat CKD model.

                            Brand Name : KBP-5074

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 22, 2020

                            Lead Product(s) : KBP-5074

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase II

                            Recipient : KBP Biosciences

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Labcorp Drug Development

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                            Lead Product(s) : KBP-5074

                            Therapeutic Area : Nephrology

                            Study Phase : Phase II

                            Recipient : KBP Biosciences

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            KBP Biosciences Announces Publication of Trial Design Manuscript for Ongoing BLOCK CKD Phase 2b Study of KBP-5...

                            Details : BLOCK-CKD is a Phase 2b, international, multicenter, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of KBP-5074, on top of current therapy, in patients with Stage 3B/4 CKD and uncontrolled hypertens...

                            Brand Name : KBP-5074

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 29, 2020

                            Lead Product(s) : KBP-5074

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase II

                            Recipient : KBP Biosciences

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Labcorp Drug Development

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                            Lead Product(s) : KBP-5074

                            Therapeutic Area : Nephrology

                            Study Phase : Phase II

                            Recipient : KBP Biosciences

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            KBP Biosciences’ KBP-5074 Appears Well Tolerated in a single dose PK Study in severe CKD patients with and w...

                            Details : Single doses of 0.5 mg KBP-5074 were generally well tolerated in patients with severe CKD, with or without hemodialysis . Overall drug exposure was significantly lower in hemodialyzed patients vs. non-hemodialyzed patients.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 21, 2020

                            Lead Product(s) : KBP-5074

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase II

                            Recipient : KBP Biosciences

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : KBP-5074

                            Therapeutic Area : Nephrology

                            Study Phase : Phase II

                            Recipient : KBP Biosciences

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            KBP Biosciences Completes Enrollment of BLOCK CKD Phase 2b Study of KBP-5074

                            Details : BLOCK CKD is a randomized, double-blind, placebo-controlled, multi-center study to assess the efficacy, safety, and pharmacokinetics of KBP-5074 in patients with moderate-to-severe CKD and uncontrolled hypertension.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 20, 2020

                            Lead Product(s) : KBP-5074

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase II

                            Recipient : KBP Biosciences

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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