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    [{"orgOrder":0,"company":"Laboratoires Thea","sponsor":"OliX Pharmaceutical","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"SOUTH KOREA","productType":"Cell and Gene therapy","year":"2020","type":"Licensing Agreement","leadProduct":"OLX301A","moa":"","graph1":"Ophthalmology","graph2":"Preclinical","graph3":"Laboratoires Thea","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"","sponsorNew":"Laboratoires Thea \/ Laboratoires Th\u00e9a","highestDevelopmentStatusID":"4","companyTruncated":"Laboratoires Thea \/ Laboratoires Th\u00e9a"},{"orgOrder":0,"company":"Laboratoires Thea","sponsor":"Ripple Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"CANADA","productType":"Small molecule","year":"2020","type":"Licensing Agreement","leadProduct":"Dexamethasone","moa":"Glucocorticoid receptor","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Laboratoires Thea","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Implant","sponsorNew":"Laboratoires Thea \/ Th\u00e9a Open Innovation","highestDevelopmentStatusID":"8","companyTruncated":"Laboratoires Thea \/ Th\u00e9a Open Innovation"},{"orgOrder":0,"company":"Laboratoires Thea","sponsor":"Ripple Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"CANADA","productType":"Small molecule","year":"2020","type":"Series A Financing","leadProduct":"Dexamethasone","moa":"Glucocorticoid receptor","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Laboratoires Thea","amount2":0.02,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0.02,"dosageForm":"Intravitreal Implant","sponsorNew":"Laboratoires Thea \/ Th\u00e9a Open Innovation","highestDevelopmentStatusID":"8","companyTruncated":"Laboratoires Thea \/ Th\u00e9a Open Innovation"},{"orgOrder":0,"company":"Laboratoires Thea","sponsor":"Nevakar","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Collaboration","leadProduct":"Atropine","moa":"","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Laboratoires Thea","amount2":0.14000000000000001,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0.14000000000000001,"dosageForm":"Eye Drop","sponsorNew":"Laboratoires Thea \/ Laboratoires Th\u00e9a","highestDevelopmentStatusID":"10","companyTruncated":"Laboratoires Thea \/ Laboratoires Th\u00e9a"},{"orgOrder":0,"company":"Laboratoires Thea","sponsor":"Coave Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"FRANCE","productType":"Cell and Gene therapy","year":"2021","type":"Licensing Agreement","leadProduct":"CTx-PDE6b","moa":"PDE6B gene","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Laboratoires Thea","amount2":0.089999999999999997,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0.089999999999999997,"dosageForm":"Intravitreal","sponsorNew":"Laboratoires Thea \/ Th\u00e9a","highestDevelopmentStatusID":"7","companyTruncated":"Laboratoires Thea \/ Th\u00e9a"},{"orgOrder":0,"company":"Laboratoires Thea","sponsor":"Vyluma","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Licensing Agreement","leadProduct":"Atropine","moa":"Muscarinic M3 receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Laboratoires Thea","amount2":0.14999999999999999,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0.14999999999999999,"dosageForm":"Solution\/Drops","sponsorNew":"Laboratoires Thea \/ Laboratoires Th\u00e9a","highestDevelopmentStatusID":"10","companyTruncated":"Laboratoires Thea \/ Laboratoires Th\u00e9a"},{"orgOrder":0,"company":"Laboratoires Thea","sponsor":"Vyluma","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Atropine","moa":"ACh receptor","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Laboratoires Thea","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution\/Drops","sponsorNew":"Laboratoires Thea \/ Laboratories Thea","highestDevelopmentStatusID":"10","companyTruncated":"Laboratoires Thea \/ Laboratories Thea"},{"orgOrder":0,"company":"Thea Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Latanoprost","moa":"","graph1":"Ophthalmology","graph2":"Approved","graph3":"Thea Pharma","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Thea Pharma \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Thea Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Thea Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Latanoprost","moa":"","graph1":"Ophthalmology","graph2":"Approved","graph3":"Thea Pharma","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Thea Pharma \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Thea Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Thea Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Latanoprost","moa":"","graph1":"Ophthalmology","graph2":"Approved","graph3":"Thea Pharma","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution","sponsorNew":"Thea Pharma \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Thea Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Laboratoires Thea","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"FRANCE","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Bimatoprost","moa":"","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Laboratoires Thea","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Solution\/Drops","sponsorNew":"Laboratoires Thea \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Laboratoires Thea \/ Not Applicable"},{"orgOrder":0,"company":"Thea Pharma","sponsor":"Akorn Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"HPAPI","year":"2022","type":"Acquisition","leadProduct":"Tafluprost","moa":"FP receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Thea Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Thea Pharma \/ Thea Pharma","highestDevelopmentStatusID":"15","companyTruncated":"Thea Pharma \/ Thea Pharma"},{"orgOrder":0,"company":"Laboratoires Thea","sponsor":"Akorn Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"HPAPI","year":"2022","type":"Acquisition","leadProduct":"Tafluprost","moa":"FP receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Laboratoires Thea","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Laboratoires Thea \/ Laboratoires Thea","highestDevelopmentStatusID":"15","companyTruncated":"Laboratoires Thea \/ Laboratoires Thea"},{"orgOrder":0,"company":"Thea Pharma","sponsor":"Prasco Laboratories","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"HPAPI","year":"2022","type":"Inapplicable","leadProduct":"Tafluprost","moa":"FP receptor","graph1":"Ophthalmology","graph2":"Approved FDF","graph3":"Thea Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Solution","sponsorNew":"Thea Pharma \/ Thea Pharma","highestDevelopmentStatusID":"15","companyTruncated":"Thea Pharma \/ Thea Pharma"},{"orgOrder":0,"company":"Laboratoires Thea","sponsor":"ProQR Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Rare Diseases and Disorders","country":"NETHERLANDS","productType":"Oligonucleotide","year":"2023","type":"Divestment","leadProduct":"Sepofarsen","moa":"CEP290","graph1":"Rare Diseases and Disorders","graph2":"Phase II\/ Phase III","graph3":"Laboratoires Thea","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Laboratoires Thea \/ Laboratoires Thea","highestDevelopmentStatusID":"9","companyTruncated":"Laboratoires Thea \/ Laboratoires Thea"},{"orgOrder":0,"company":"Laboratoires Thea","sponsor":"ProQR Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Rare Diseases and Disorders","country":"NETHERLANDS","productType":"Oligonucleotide","year":"2023","type":"Divestment","leadProduct":"Sepofarsen","moa":"CEP290","graph1":"Rare Diseases and Disorders","graph2":"Phase II\/ Phase III","graph3":"Laboratoires Thea","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Laboratoires Thea \/ Laboratoires Thea","highestDevelopmentStatusID":"9","companyTruncated":"Laboratoires Thea \/ Laboratoires Thea"}]

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                            01

                            Laboratoires Thea

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                            Lead Product(s) : Sepofarsen

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase II/ Phase III

                            Recipient : ProQR Therapeutics

                            Deal Size : $186.3 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            ProQR Therapeutics Announces Transaction Completed for Théa to Acquire Sepofarsen and Ultevursen Ophthalmic A...

                            Details : The divestment provides Théa with ProQR's late stage ophthalmic assets, QR-110 (sepofarsen) and QR-421a (ultevursen) for patients with rare genetic eye diseases and supports ProQR’s strategic focus on the Axiomer® RNA editing technology platform.

                            Product Name : QR-110

                            Product Type : Oligonucleotide

                            Upfront Cash : $8.6 million

                            December 08, 2023

                            Lead Product(s) : Sepofarsen

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase II/ Phase III

                            Recipient : ProQR Therapeutics

                            Deal Size : $186.3 million

                            Deal Type : Divestment

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                            02

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                            Lead Product(s) : Bimatoprost

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Bimatoprost by Laboratoires Thea for Open-Angle Glaucoma: Likelihood of Approval

                            Details : T-4032 (bimatoprost) is under development for the treatment of open-angle glaucoma and ocular hypertension. It is administered by ophthalmic route as drops. It acts by targeting prostaglandin F2 alpha.

                            Product Name : T4032

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 27, 2023

                            Lead Product(s) : Bimatoprost

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Thea Pharma

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                            Lead Product(s) : Latanoprost

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Thea Pharma Inc. Launches IYUZEH™ (latanoprost ophthalmic solution) 0.005% in the U.S.

                            Details : Iyuzeh (latanoprost) is a prostaglandin F2α analogue that is believed to reduce the IOP by increasing the outflow of aqueous humor. It is being indicated for primary open-angle glaucoma (POAG) or ocular hypertension (OHT).

                            Product Name : Iyuzeh

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 26, 2023

                            Lead Product(s) : Latanoprost

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

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                            Lead Product(s) : Sepofarsen

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase II/ Phase III

                            Recipient : ProQR Therapeutics

                            Deal Size : $162.0 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            ProQR Therapeutics and Laboratoires Théa Announce Agreement for Théa to Acquire ProQR’s Sepofarsen and Ult...

                            Details : The divestment provides Théa with ProQR's late stage ophthalmic assets, QR-110 (sepofarsen) and QR-421a (ultevursen) for patients with rare genetic eye diseases and supports ProQR’s strategic focus on the Axiomer® RNA editing technology platform.

                            Product Name : QR-110

                            Product Type : Oligonucleotide

                            Upfront Cash : $13.7 million

                            August 01, 2023

                            Lead Product(s) : Sepofarsen

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase II/ Phase III

                            Recipient : ProQR Therapeutics

                            Deal Size : $162.0 million

                            Deal Type : Divestment

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                            05

                            Thea Pharma

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                            Lead Product(s) : Latanoprost

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            IYUZEH™ (Latanoprost Ophthalmic Solution) 0.005%, The First and Only Preservative-Free Latanoprost Ophthalmi...

                            Details : Iyuzeh (latanoprost) is a prostaglandin F2α analogue that is believed to reduce the IOP by increasing the outflow of aqueous humor. It is being indicated for primary open-angle glaucoma (POAG) or ocular hypertension (OHT).

                            Product Name : Iyuzeh

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 03, 2023

                            Lead Product(s) : Latanoprost

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Thea Pharma

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                            Thea Pharma

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                            Lead Product(s) : Latanoprost

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Thea Pharma Announces FDA Approval of IYUZEH™ for the Reduction of Elevated Intraocular Pressure (IOP) in Pa...

                            Details : IYUZEH™ is the first and only clinically proven formulation of latanoprost available in the United States that is preservative-free. IYUZEH™ is formulated without any of the preservatives commonly used in topical ocular preparations, including benzal...

                            Product Name : Iyuzeh

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 14, 2022

                            Lead Product(s) : Latanoprost

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Thea Pharma

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                            Lead Product(s) : Tafluprost

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved FDF

                            Recipient : Prasco Laboratories

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Prasco Launches Authorized Generic of ZIOPTAN® Ophthalmic Solution

                            Details : Tafluprost Ophthalmic Solution 0.0015% is a prostaglandin analog indicated for reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

                            Product Name : Tafluprost-Generic

                            Product Type : HPAPI

                            Upfront Cash : Inapplicable

                            November 18, 2022

                            Lead Product(s) : Tafluprost

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved FDF

                            Recipient : Prasco Laboratories

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Laboratoires Thea

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                            Lead Product(s) : Atropine

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase III

                            Recipient : Vyluma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Vyluma Announces Positive Results From Phase III CHAMP Study of NVK002 for Treatment of Myopia Progression in ...

                            Details : NVK002 (atropine) is a proprietary, investigational, low-dose, preservative-free atropine eye drop administered nightly as a potential treatment for the progression of myopia in children.

                            Product Name : NVK-002

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 27, 2022

                            Lead Product(s) : Atropine

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase III

                            Recipient : Vyluma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Laboratoires Thea

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                            Laboratoires Thea

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                            Lead Product(s) : Atropine

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase III

                            Recipient : Vyluma

                            Deal Size : $150.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Vyluma and Laboratoires Thea Enter into Licensing Agreement for the Registration and Commercialization of NVK0...

                            Details : The agreement represents an expansion of the previously announced exclusive licensing agreement for the commercialization of NVK002 (having Atropine) in Europe and other select countries.

                            Product Name : NVK002

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 14, 2022

                            Lead Product(s) : Atropine

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase III

                            Recipient : Vyluma

                            Deal Size : $150.0 million

                            Deal Type : Licensing Agreement

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                            10

                            Thea Pharma

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                            Thea Pharma

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                            Lead Product(s) : Tafluprost

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved FDF

                            Recipient : Akorn Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Akorn Announces Completion of the Sale of its Branded Ophthalmic Products to Théa Pharma

                            Details : Under the deal, Théa Pharma acquired seven products including established glaucoma therapies Zioptan®, Cosopt®, Cosopt® PF, and Betimol®, along with Azasite®, Akten®, and the ocular surface repair agent AcellFX™.

                            Product Name : Zioptan

                            Product Type : HPAPI

                            Upfront Cash : Undisclosed

                            March 09, 2022

                            Lead Product(s) : Tafluprost

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved FDF

                            Recipient : Akorn Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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