Innate Pharma Announces U.S. FDA Lifts Partial Clinical Hold on Lacutamab Clinical Program
Details : IPH4102 (lacutamab) is an anti-KIR3DL2 humanized antibody in phase 2 trials for cutaneous T-cell lymphoma and peripheral T-cell lymphoma treatment.
Brand Name : IPH4102
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 03, 2024
Innate Pharma Provides Update on Lacutamab Clinical Program
Details : IPH4102 (lacutamab) is a first-in-class anti-KIR3DL2 humanized cytotoxicity-inducing antibody that is currently in clinical trials for treatment of cutaneous T-cell lymphoma (CTCL), an orphan disease, and peripheral T cell lymphoma (PTCL).
Brand Name : IPH4102
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 05, 2023
Details : Lacutamab (IPH4102) is a first-in-class anti-KIR3DL2 humanized cytotoxicity-inducing antibody that is currently in clinical trials for treatment of cutaneous T-cell lymphoma (CTCL), an orphan disease, and peripheral T cell lymphoma (PTCL).
Brand Name : IPH4102
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 10, 2022
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Innate Pharma to Present Lacutamab PTCL Phase 1b Design and ANKET™ Platform at ESMO 2022
Details : Lacutamab (IPH4102) is a first-in-class anti-KIR3DL2 humanized cytotoxicity-inducing antibody that is currently in clinical trials for treatment of cutaneous T-cell lymphoma (CTCL), an orphan disease, and peripheral T cell lymphoma (PTCL).
Brand Name : IPH4102
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 05, 2022
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Lacutamab demonstrated clinical responses in patients with MF that express KIR3DL2 (cohort 2), reaching the pre-determined threshold to advance to stage 2.
Brand Name : IPH4102
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 22, 2021
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Lacutamab (IPH4102) is a first-in-class anti-KIR3DL2 humanized cytotoxicity-inducing antibody, which is currently in clinical trials for treatment of cutaneous T-cell lymphoma (CTCL), an orphan disease.
Brand Name : IPH4102
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 09, 2021
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Innate Pharma Advances Lacutamab Clinical Development Program
Details : Company to initiate two new clinical trials to investigate lacutamab in peripheral T-cell lymphoma, including Phase 2 combination study with leading global lymphoma research network, LYSA.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 09, 2021
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The FDA decision is based on a quality assessment of a new Good Manufacturing Practice (GMP)-certified batch that has been successfully manufactured for the lacutamab clinical development program, including the TELLOMAK trial.
Brand Name : IPH4102
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 24, 2020
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Innate Pharma will take the operational measures to reactivate the lacutamab TELLOMAK trial in Sézary syndrome and MF in France and UK, where regulatory agencies have authorized it.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 13, 2020
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Innate Pharma Provides Update from Regulatory Agencies on Lacutamab TELLOMAK Trial
Details : Innate Pharma decided to suspend enrollment of new patients in the TELLOMAK trial, except in Italy where the clinical trial has been suspended.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 09, 2020
Lead Product(s) : Lacutamab,Gemcitabine,Oxaliplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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