Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : ImmunityBio
Deal Size : $356.0 million
Deal Type : Termination
LadRx and ImmunityBio Mutually Agree to Terminate Aldoxorubicin License
Details : With the termination, LadRx regains control of INNO-206 (aldoxorubicin), a rationally-engineered cytotoxic which delivers well-established anti-cancer agent, doxorubicin, into the tumor.
Brand Name : INNO-206
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 03, 2024
Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : ImmunityBio
Deal Size : $356.0 million
Deal Type : Termination
Lead Product(s) : Arimoclomol
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase II/ Phase III
Sponsor : XOMA
Deal Size : $58.6 million
Deal Type : Agreement
FDA Accepts Zevra's Arimoclomol NDA for NPC Type C, Triggering Milestone Payment
Details : XOMA acquired royalty and milestone rights for LadRx Corporation’s BRX-345 (arimoclomol) for Niemann-Pick Disease Type C, and aldoxorubicin, an albumin-linked formulation of doxorubicin.
Brand Name : BRX-345
Molecule Type : Small molecule
Upfront Cash : $5.0 million
January 11, 2024
Lead Product(s) : Arimoclomol
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase II/ Phase III
Sponsor : XOMA
Deal Size : $58.6 million
Deal Type : Agreement
Lead Product(s) : AE-Keto-Sulf07
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : XOMA
Deal Size : $11.0 million
Deal Type : Financing
LadRx Completes Non-Dilutive Financing Transaction for up to $11 Million with XOMA Corporation
Details : The Company expects to use the proceeds to advance its lead novel LADR-based anti-cancer drug, LADR-7 (AE-keto-sulf07) towards an IND filing with the FDA.
Brand Name : LADR7
Molecule Type : Large molecule
Upfront Cash : Undisclosed
June 22, 2023
Lead Product(s) : AE-Keto-Sulf07
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : XOMA
Deal Size : $11.0 million
Deal Type : Financing
Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
LadRx Highlights Patent Issued for Its LADR Technology
Details : INNO-206 (aldoxorubicin) is a prodrug of doxorubicin that binds endogenous albumin after administration. The bound doxorubicin is released in the acidic environment of the tumor cell through cleavage of an acid sensitive linker and expresses antitumor ef...
Brand Name : INNO-206
Molecule Type :
Upfront Cash : Not Applicable
March 27, 2023
Lead Product(s) : Aldoxorubicin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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