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    [{"orgOrder":0,"company":"Landos Biopharma","sponsor":"LianBio","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Collaboration","leadProduct":"Omilancor","moa":"LANCL2","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Landos Biopharma","amount2":0.22,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0.22,"dosageForm":"Tablet","sponsorNew":"Landos Biopharma \/ LianBio","highestDevelopmentStatusID":"8","companyTruncated":"Landos Biopharma \/ LianBio"},{"orgOrder":0,"company":"Landos Biopharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Omilancor","moa":"LANCL2","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Landos Biopharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Landos Biopharma \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Landos Biopharma \/ Not Applicable"},{"orgOrder":0,"company":"Landos Biopharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"LABP-104","moa":"LANCL2","graph1":"Immunology","graph2":"Phase I","graph3":"Landos Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Landos Biopharma \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Landos Biopharma \/ Not Applicable"},{"orgOrder":0,"company":"Landos Biopharma","sponsor":"Icahn School of Medicine","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Small 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Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Landos Biopharma \/ Not Applicable"},{"orgOrder":0,"company":"Landos Biopharma","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Private Placement","leadProduct":"NX-13","moa":"","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Landos Biopharma","amount2":0.02,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0.02,"dosageForm":"Tablet","sponsorNew":"Landos Biopharma \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Landos Biopharma \/ Undisclosed"},{"orgOrder":0,"company":"Landos Biopharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"NX-13","moa":"","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Landos Biopharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Immediate-Release Tablet","sponsorNew":"Landos Biopharma \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Landos Biopharma \/ Not Applicable"},{"orgOrder":0,"company":"Landos Biopharma","sponsor":"NImmune Biopharma","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Omilancor","moa":"","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Landos Biopharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Landos Biopharma \/ NImmune Biopharma","highestDevelopmentStatusID":"8","companyTruncated":"Landos Biopharma \/ NImmune Biopharma"},{"orgOrder":0,"company":"Landos Biopharma","sponsor":"KU Leuven","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Collaboration","leadProduct":"NX-13","moa":"","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Landos Biopharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Landos Biopharma \/ KU Leuven","highestDevelopmentStatusID":"8","companyTruncated":"Landos Biopharma \/ KU Leuven"},{"orgOrder":0,"company":"Landos Biopharma","sponsor":"AbbVie Inc","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Acquisition","leadProduct":"NX-13","moa":"","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Landos Biopharma","amount2":0.20999999999999999,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0.20999999999999999,"dosageForm":"Tablet","sponsorNew":"Landos Biopharma \/ Abbvie Inc","highestDevelopmentStatusID":"8","companyTruncated":"Landos Biopharma \/ Abbvie Inc"}]

    Find Clinical Drug Pipeline Developments & Deals by Landos Biopharma

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                            01

                            Landos Biopharma

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                            Lead Product(s) : NX-13

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : AbbVie Inc

                            Deal Size : $212.5 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            AbbVie To Acquire Landos Biopharma, Strengthening Portfolio in Inflammatory Diseases

                            Details : AbbVie will advance Landos’ lead investigational asset NX-13, a first-in-class, oral NLRX1 agonist with a bimodal mechanism of action, which is anti-inflammatory and facilitates epithelial repair.

                            Brand Name : NX-13

                            Molecule Type : Small molecule

                            Upfront Cash : $137.5 million

                            March 25, 2024

                            Lead Product(s) : NX-13

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : AbbVie Inc

                            Deal Size : $212.5 million

                            Deal Type : Acquisition

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                            02

                            Landos Biopharma

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                            Lead Product(s) : NX-13

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : KU Leuven

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Landos Biopharma Announces Strategic Research Collaboration with KU Leuven and University Hospitals Leuven to ...

                            Details : The collaboration aims to investigate the effects of NX-13, first-in-class, oral, gut-selective, NLRX1 agonist, on epithelial cells with the Inflammatory Bowel Disease.

                            Brand Name : NX-13

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            September 14, 2023

                            Lead Product(s) : NX-13

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : KU Leuven

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            03

                            Landos Biopharma

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                            Lead Product(s) : Omilancor

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : NImmune Biopharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Josep Bassaganya-Riera Launches NImmune Biopharma with Phase 3-Ready Clinical Candidate Omilancor for the Trea...

                            Details : BT-11 (omilancor) is a novel, oral, gut-restricted therapeutic targeting the lanthionine synthetase C-like 2 (LANCL2) pathway which decreases the production of key inflammatory mediators causing ulcerative colitis.

                            Brand Name : BT-11

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 22, 2023

                            Lead Product(s) : Omilancor

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : NImmune Biopharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Landos Biopharma

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                            Lead Product(s) : NX-13

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Landos Biopharma Announces Acceptance of Abstract on NX-13 Phase 1b Study in Ulcerative Colitis at 18th Annual...

                            Details : NX-13 is a first-in-class novel, gut-selective oral therapeutic candidate that targets NLRX1 that has been associated with the modulation of inflammatory cytokines for UC and CD.

                            Brand Name : NX-13

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 11, 2023

                            Lead Product(s) : NX-13

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Landos Biopharma

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                            Landos Biopharma

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                            Lead Product(s) : NX-13

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : $16.7 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Landos Biopharma Announces $16.7 Million Private Placement Financing

                            Details : Landos Biopharma anticipates using the net proceeds from the investment to advance the development of NX-13 for Ulcerative Colitis and Crohn’s Disease and for other general corporate purposes.

                            Brand Name : NX-13

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            January 05, 2023

                            Lead Product(s) : NX-13

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : $16.7 million

                            Deal Type : Private Placement

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                            Lead Product(s) : NX-13

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Landos Biopharma Reports Positive Top-Line Results From NX-13 Phase 1b Trial

                            Details : NX-13 is a novel, gut-restricted, orally active, small molecule therapeutic candidate for the treatment of UC. NX-13 targets NLRX1, a mitochondria-associated receptor with the ability to modulate immune responses.

                            Brand Name : NX-13

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 03, 2022

                            Lead Product(s) : NX-13

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Landos Biopharma

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                            Lead Product(s) : Omilancor

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Icahn School of Medicine

                            Deal Size : $3.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Landos Biopharma to Collaborate on a Phase 2 Study of Omilancor in Crohn’s Disease with the Icahn School of ...

                            Details : Landos Biopharma collaborate with Icahn School of Medicine to conduct a Phase 2 trial of omilancor, a novel, oral, gut-restricted, small-molecule investigational drug that targets the Lanthionine Synthetase C-Like 2 (LANCL2) pathway impacting the gastroi...

                            Brand Name : BT-11

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            September 20, 2021

                            Lead Product(s) : Omilancor

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Icahn School of Medicine

                            Deal Size : $3.0 million

                            Deal Type : Collaboration

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                            Lead Product(s) : LABP-104

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Landos Biopharma to Present Results of LABP-104 in Lupus at the American College of Rheumatology Convergence 2...

                            Details : Oral treatment with LABP-104 in preclinical models of Systemic Lupus Erythematosus (SLE) resulted in enhanced Treg function, decreased kidney inflammation and reduced interferon gamma signaling.

                            Brand Name : LABP-104

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 15, 2021

                            Lead Product(s) : LABP-104

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Landos Biopharma

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                            Lead Product(s) : Omilancor

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Landos Phase 2 Data of Omilancor in Ulcerative Colitisr Oral Presentation

                            Details : Discovered using Landos proprietary LANCE® Advanced A.I. platform, omilancor is a novel, oral, gut-restricted small molecule investigational drug that targets the Lanthionine Synthetase C-Like 2 (LANCL2) pathway impacting the gastrointestinal tract.

                            Brand Name : BT-11

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 22, 2021

                            Lead Product(s) : Omilancor

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Landos Biopharma

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                            Lead Product(s) : Omilancor

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : LianBio

                            Deal Size : $218.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Landos Biopharma and LianBio Announce Exclusive Collaboration and License Agreement for Omilancor and NX-13

                            Details : LianBio will receive exclusive rights to develop and commercialize BT-11 and NX-13 in Greater China, South Korea, Singapore, Thailand, Vietnam, Myanmar, Cambodia, Indonesia, and the Philippines.

                            Brand Name : BT-11

                            Molecule Type : Small molecule

                            Upfront Cash : $18.0 million

                            May 17, 2021

                            Lead Product(s) : Omilancor

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : LianBio

                            Deal Size : $218.0 million

                            Deal Type : Collaboration

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