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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The financing is intended to support the clinical development of LM-302, an anti-CLDN 18.2 ADC, which is currently in late-stage clinical trials in China for the treatment of gastric cancers.

                          Brand Name : LM-302

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          October 18, 2024

                          Lead Product(s) : LM-302,Rivoceranib,Irinotecan Hydrochloride

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Sino Biopharmaceutical

                          Deal Size : $42.0 million

                          Deal Type : Series C Financing

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Under the terms of the licensing agreement, AstraZeneca will be granted an exclusive global license to research, develop, and commercialize LM-305, a pre-clinical stage antibody drug conjugate (ADC) targeting G protein-coupled receptor, class C, group 5,...

                          Brand Name : LM-305

                          Molecule Type : Large molecule

                          Upfront Cash : $55.0 million

                          May 12, 2023

                          Lead Product(s) : LM-305,Dexamethasone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : AstraZeneca

                          Deal Size : $600.0 million

                          Deal Type : Licensing Agreement

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : TPX-4589 (LM-302) is a potentially first-in-class anti-Claudin18.2 ADC discovered by LaNova that suppresses cell proliferation of gastric and pancreatic cell lines with nanomolar potency in preclinical models. It also has demonstrated efficacy in gastric...

                          Brand Name : TPX-4589

                          Molecule Type : Large molecule

                          Upfront Cash : $25.0 million

                          May 05, 2022

                          Lead Product(s) : LM-302

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Turning Point Therapeutics

                          Deal Size : $220.0 million

                          Deal Type : Licensing Agreement

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