Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : LM-299
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Merck & Co
Deal Size : $3,288.0 million
Deal Type : Licensing Agreement
Merck Signs Up to $3.3 Billion Cancer Drug Deal with China-Based Lanova
Details : Merck will acquire the global rights to develop and market LM-299, a novel investigational PD-1/VEGF bispecific antibody, for the treatment of advanced solid tumours.
Brand Name : LM-299
Molecule Type : Large molecule
Upfront Cash : $588.0 million
November 16, 2024
Lead Product(s) : LM-299
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Merck & Co
Deal Size : $3,288.0 million
Deal Type : Licensing Agreement
Lead Product(s) : LM-302,Rivoceranib,Irinotecan Hydrochloride
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Sino Biopharmaceutical
Deal Size : $42.0 million
Deal Type : Series C Financing
LaNova Initiates Phase 1 for LM-299 Anti-PD-1/VEGF Antibody and $42M Financing
Details : The financing is intended to support the clinical development of LM-302, an anti-CLDN 18.2 ADC, which is currently in late-stage clinical trials in China for the treatment of gastric cancers.
Brand Name : LM-302
Molecule Type : Large molecule
Upfront Cash : Undisclosed
October 18, 2024
Lead Product(s) : LM-302,Rivoceranib,Irinotecan Hydrochloride
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Sino Biopharmaceutical
Deal Size : $42.0 million
Deal Type : Series C Financing
Lead Product(s) : LM-305,Dexamethasone
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : AstraZeneca
Deal Size : $600.0 million
Deal Type : Licensing Agreement
Details : Under the terms of the licensing agreement, AstraZeneca will be granted an exclusive global license to research, develop, and commercialize LM-305, a pre-clinical stage antibody drug conjugate (ADC) targeting G protein-coupled receptor, class C, group 5,...
Brand Name : LM-305
Molecule Type : Large molecule
Upfront Cash : $55.0 million
May 12, 2023
Lead Product(s) : LM-305,Dexamethasone
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : AstraZeneca
Deal Size : $600.0 million
Deal Type : Licensing Agreement
Lead Product(s) : LM-302
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Turning Point Therapeutics
Deal Size : $220.0 million
Deal Type : Licensing Agreement
Details : TPX-4589 (LM-302) is a potentially first-in-class anti-Claudin18.2 ADC discovered by LaNova that suppresses cell proliferation of gastric and pancreatic cell lines with nanomolar potency in preclinical models. It also has demonstrated efficacy in gastric...
Brand Name : TPX-4589
Molecule Type : Large molecule
Upfront Cash : $25.0 million
May 05, 2022
Lead Product(s) : LM-302
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Turning Point Therapeutics
Deal Size : $220.0 million
Deal Type : Licensing Agreement
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