Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : [68Ga]-Trivehexin
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Radiopharm Theranostics
Deal Size : $18.0 million
Deal Type : Private Placement
Radiopharm Receives Strategic Investment for up to A$18 million
Details : The company will use the net proceeds of Lantheus’ investment for drug advancement RAD301 ([68Ga]-Trivehexin), which is being evaluated for treating pancreatic neoplasms.
Brand Name : RAD301
Molecule Type : Large molecule
Upfront Cash : Undisclosed
June 19, 2024
Lead Product(s) : [68Ga]-Trivehexin
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Radiopharm Theranostics
Deal Size : $18.0 million
Deal Type : Private Placement
Lead Product(s) : Dotatate Lutenium Lu-177
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lantheus Announces Acceptance of ANDA for Generic LUTATHERA®
Details : Lutathera-Generic (Lutetium Lu 177 Dotatate) is a radiolabeled somatostatin analog for treating somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors.
Brand Name : Lutathera-Generic
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 11, 2024
Lead Product(s) : Dotatate Lutenium Lu-177
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 212Pb-VMT-alpha-NET
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Perspective Therapeutics
Deal Size : $61.0 million
Deal Type : Agreement
Lantheus Expands Radiopharmaceutical Oncology Pipeline through Strategic Agreements
Details : Under the agreement, Lantheus obtains an exclusive license for Perspective’s Pb212-VMT-⍺-NET, a clinical-stage alpha therapy developed for the treatment of neuroendocrine tumors.
Brand Name : 212Pb-VMT-alpha-NET
Molecule Type : Small molecule
Upfront Cash : $28.0 million
January 09, 2024
Lead Product(s) : 212Pb-VMT-alpha-NET
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Perspective Therapeutics
Deal Size : $61.0 million
Deal Type : Agreement
Lead Product(s) : [Lu-177]-PNT2002
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Point Biopharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PNT2002 (Lu-177-PSMA-I&T) is a PSMA-Targeted therapy under phase 3 clinical development for metastatic castration-resistant prostate cancer (mCRPC). PNT2002 combines a PSMA-targeted ligand, PSMA-I&T, with the beta-emitting radioisotope lutetium-177.
Brand Name : [Lu-177]-PSMA-I&T
Molecule Type : Undisclosed
Upfront Cash : Not Applicable
December 18, 2023
Lead Product(s) : [Lu-177]-PNT2002
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Point Biopharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lutetium (177Lu) Zadavotide Guraxetan
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : Point Biopharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PNT2002 (Lu-177-PSMA-I&T) is a PSMA-Targeted therapy for metastatic castration-resistant prostate cancer (mCRPC). PNT2002 combines a PSMA-targeted ligand, PSMA-I&T, with the beta-emitting radioisotope lutetium-177.
Brand Name : PNT2002
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 24, 2023
Lead Product(s) : Lutetium (177Lu) Zadavotide Guraxetan
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : Point Biopharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Lutetium (177Lu) Zadavotide Guraxetan
Therapeutic Area : Oncology
Study Phase : Phase III
Recipient : Point Biopharma
Deal Size : $2,115.0 million
Deal Type : Collaboration
Details : Lu-177-PSMA-I&T (Lu-177-PNT2002) is a PSMA-Targeted therapy for mCRPC. PSMA is overexpressed in the vast majority of prostate cancers, but very limited to normal tissues. PNT2002 combines a PSMA-targeted ligand, PSMA-I&T, with the beta-emitting radioisot...
Brand Name : 177Lu-PSMA-I&T
Molecule Type : Large molecule
Upfront Cash : $260.0 million
November 14, 2022
Lead Product(s) : Lutetium (177Lu) Zadavotide Guraxetan
Therapeutic Area : Oncology
Highest Development Status : Phase III
Recipient : Point Biopharma
Deal Size : $2,115.0 million
Deal Type : Collaboration
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Collaboration
Lantheus Announces Collaboration to Support Prostate Cancer Clinical Development
Details : As part of the agreement with Novartis, Lantheus will provide PYLARIFY for the selection of patients with prostate cancer and Novartis will provide all PYLARIFY related clinical imaging data to Lantheus.
Brand Name : Pluvicto
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 29, 2022
Lead Product(s) : Lutetium-177 Vipivotide Tetraxetan
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Collaboration
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