[{"orgOrder":0,"company":"Leaps by Bayer","sponsor":"Senti Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Financing","leadProduct":"SENTI-202","moa":"IL-15","graph1":"Oncology","graph2":"Preclinical","graph3":"Leaps by Bayer","amount2":0.01,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.01,"dosageForm":"","sponsorNew":"Leaps by Bayer \/ Leaps by Bayer","highestDevelopmentStatusID":"4","companyTruncated":"Leaps by Bayer \/ Leaps by Bayer"},{"orgOrder":0,"company":"Leaps by Bayer","sponsor":"ReCode Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Rare Diseases and Disorders","country":"","productType":"Large molecule","year":"2022","type":"Series B Financing","leadProduct":"SORT LNP-based DNAI1 mRNA Therapeutic","moa":"","graph1":"Rare Diseases and Disorders","graph2":"Preclinical","graph3":"Leaps by Bayer","amount2":0.20000000000000001,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Rare Diseases","amount2New":0.20000000000000001,"dosageForm":"Aerosol","sponsorNew":"Leaps by Bayer \/ Leaps by Bayer","highestDevelopmentStatusID":"4","companyTruncated":"Leaps by Bayer \/ Leaps by Bayer"},{"orgOrder":0,"company":"Leaps by Bayer","sponsor":"NextPoint","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Undisclosed","year":"2023","type":"Series B Financing","leadProduct":"Undisclosed","moa":"","graph1":"Oncology","graph2":"Undisclosed","graph3":"Leaps by Bayer","amount2":0.080000000000000002,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Oncology","amount2New":0.080000000000000002,"dosageForm":"","sponsorNew":"Leaps by Bayer \/ Leaps by Bayer","highestDevelopmentStatusID":"1","companyTruncated":"Leaps by Bayer \/ Leaps by Bayer"},{"orgOrder":0,"company":"Leaps by Bayer","sponsor":"Boundless Bio","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2023","type":"Series C Financing","leadProduct":"ecDNA-directed Therapy","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Leaps by Bayer","amount2":0.10000000000000001,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Leaps by Bayer \/ Leaps by Bayer","highestDevelopmentStatusID":"6","companyTruncated":"Leaps by Bayer \/ Leaps by Bayer"},{"orgOrder":0,"company":"Leaps by Bayer","sponsor":"Indapta Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2023","type":"Series A Financing","leadProduct":"Antibody","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Leaps by Bayer","amount2":0.059999999999999998,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.059999999999999998,"dosageForm":"","sponsorNew":"Leaps by Bayer \/ Leaps by Bayer","highestDevelopmentStatusID":"7","companyTruncated":"Leaps by Bayer \/ Leaps by Bayer"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The financing will be used for the first-in-human phase 1 trial of DP-023, an Allogeneic Natural Killer (NK) Cell Therapy in patients with multiple myeloma and lymphoma.

                          Brand Name : IDP-023

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          May 17, 2023

                          Lead Product(s) : IDP-023,Antibody

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Recipient : Indapta Therapeutics

                          Deal Size : $60.0 million

                          Deal Type : Series A Financing

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Boundless Bio will use the financing to advance BBI-355, a potentially best-in-class checkpoint kinase 1 inhibitor and the first ecDNA-directed therapy, through meaningful clinical readouts from its ongoing Phase 1/2 clinical trial in patients with oncog...

                          Brand Name : BBI-355

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          May 16, 2023

                          Lead Product(s) : ecDNA-directed Therapy

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Boundless Bio

                          Deal Size : $100.0 million

                          Deal Type : Series C Financing

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The financing will be used to advance NextPoint’s two lead precision immuno-oncology programs into the clinic, both targeting the newly discovered HHLA2 pathway to activate anti-tumor immune responses.

                          Brand Name : Undisclosed

                          Molecule Type : Undisclosed

                          Upfront Cash : Undisclosed

                          January 10, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Undisclosed

                          Recipient : NextPoint

                          Deal Size : $80.0 million

                          Deal Type : Series B Financing

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Proceeds from the financing will be used to fund the diversification of ReCode’s pipeline into central nervous system, liver, and oncology indications, while continuing to advance lead mRNA programs for primary ciliary dyskinesia and cystic fibrosis in...

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          June 29, 2022

                          Lead Product(s) : SORT LNP-based DNAI1 mRNA Therapeutic

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Preclinical

                          Recipient : ReCode Therapeutics

                          Deal Size : $200.0 million

                          Deal Type : Series B Financing

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Senti’s existing investors continue to support the mission of engineering gene circuits with programmable logic in cell and gene therapies, and progress in advancing multiple oncology programs including SENTI-202, towards the clinic.

                          Brand Name : SENTI-202

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          May 24, 2022

                          Lead Product(s) : SENTI-202

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Recipient : Senti Biosciences

                          Deal Size : $5.2 million

                          Deal Type : Financing

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