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Find Clinical Drug Pipeline Developments & Deals for Lenacapavir
MK-8591 (islatravir) is a non-nucleoside reverse transcriptase translocation inhibitor, which is being investigated in phase 2 for HIV-1 infection, in combination with lenacapavir.
GS-9883 (bictegravir), an HIV type 1 integrase inhibitor in combination with GS-6207 (lenacapavir), a structural capsid protein inhibitor is being evaluated for the treatment of HIV-1-infection.
Sunlenca (lenacapavir) is a selective long-acting inhibitor of HIV-1 capsid function which inhibits HIV-1 replication by interfering with multiple essential steps of the viral lifecycle.
Sunlenca (lenacapavir) is a selective long-acting inhibitor of HIV-1 capsid function which inhibits HIV-1 replication by interfering with multiple essential steps of the viral lifecycle.
Lead Product(s):Lenacapavir,Teropavimab,Zinlirvimab
Sunlenca is the first of a new class of drugs called capsid inhibitors to be FDA-approved for treating HIV-1. Sunlenca works by blocking the HIV-1 virus’ protein shell (the capsid), thereby interfering with multiple essential steps of the viral lifecycle.
Sunlenca (lenacapavir) is a first-in-class, long-acting HIV capsid inhibitor approved in the United States, the United Kingdom, Canada and the European Union, for the treatment of HIV infection, in combination with other antiretroviral.
Sunlenca (lenacapavir), is first-in-class capsid inhibitor with multi-stage mechanism of action, offering a new, every six-month treatment option for people with HIV whose virus no longer effectively responds to their current therapy.
The NDA resubmission contains comprehensive CMC data to support the compatibility of GS-6207 (lenacapavir), first-in-class, investigational long-acting HIV-1 capsid inhibitor with an alternative vial type made from aluminosilicate glass.
Recommendation is based on week 26 Data from the CAPELLA Trial showing twice-yearly GS-6207 (lenacapavir) achieved high rates of virologic suppression in heavily treatment-experienced people with HIV.
GS-6207 (Lenacapavir) is Gilead’s potential first-in-class, investigational long-acting HIV-1 capsid inhibitor in development for the treatment and prevention of HIV-1 infection. Lenacapavir was generally well tolerated in CAPELLA, with no serious adverse events.
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